全國中小學科展

2023年

探討實際執行、動作心像、動作觀察與鏡像動作時之腦部活化情形

本研究以功能性近紅外光頻譜儀,探討雙側主要運動皮質(M1)、前運動皮質(PMC)及聯合動作皮質(SMA)等動作相關腦區,以實際執行(ME)、動作心像(MI)、動作觀察(MO)及鏡像動作(MVF)等模式執行上肢功能性前伸動作(Arm reaching)時,腦部之活化情形。研究結果發現「實際執行」、「動作心像」與「鏡像動作」執行時,動作相關腦區皆顯著活化,包含M1、SMA及PMC。且可觀察到執行「動作心像」、「鏡像動作」時之大腦活化模式與「實際執行」呈現相同趨勢。此結果可應用於臨床復健訓練中,對於上肢偏癱患者(如中風患者),建議使用「鏡像動作」模式訓練,而對於雙側皆有動作障礙之患者(如頸部脊髓損傷),可使用「動作心像」作為替代治療。

Evaluation of a fiber optic distributed temperature measurement system for a geothermal energy

As part of the European project GEOTHERMICA - ERA NET and in order to assess the capacity of heat storage in Switzerland, the Centre d'Hydrogéologie et de Géothermie de l'Université de Neuchâtel (CHYN) is taking part in the HEATSTORE project, launched in 2018. The latter is expected to lead to commercial heat storage projects in the near future in Geneva and Bern, in fractured aquifers. The evaluation of the geological characteristics of these aquifers is essential to understand the thermal energy transport processes of fractured aquifers. For this, it is necessary to be able to measure the temperature distribution along boreholes. Thus, the study focuses on the evaluation of a distributed temperature system (DTS) and its optical fiber in order to determine its operation, limits and potential for use in geothermal energy. Laboratory and field tests have been carried out that the water temperature deviation measurements, with a scan time of 30 s, are reliable at less than 0.5°C at +/-5 m over 500 m of fiber. For absolute temperature values, however, a bath and a reference probe must be used to recalculate the absolute temperature to within 0.5°C. The acquired data are essential for a broader understanding of the locations of fractured and karstified aquifers at Concise, allowing the system to be used to better understand the potential for water storage at a depth of 45°C at 35 m.

Two Games on Graphs Extended from the Game of Squayles

本研究是關於 nim 遊戲的兩種推廣(其中一種是一個稱為 the game of squayles 的遊戲的推廣),稱為 edge-removing game 和 star-removing game。此遊戲為兩人遊戲。在遊戲的一開始,有一個簡單圖 G。兩個玩家輪流刪除該圖的非空路徑或非空星子圖的邊。首先不能移動的一方輸掉遊戲。 在 edge-removing game 中,我成功計算出某些特殊圖的 Grundy numbers,並給出了一般 k 星的 Grundy numbers 上界。接著我定義了一種新的圖,稱為 nice graphs,並發現所有 nice graphs 都是 N-position。我由此給出了任意兩個非空圖的 join product 的解。至於圖的 Cartesian product,我給出了兩個滿足一定條件的非空圖的 Cartesian product 的解,並發現一個 fully nice graph 和任何至少有 2 個頂點的連通圖的 Cartesian product 也是 fully nice 的。使用這個性質,我給出了 r-dimensional grids 上的 edge-removing game 的解。 至於 star-removing game,我最大的突破是構思出對稱性這個概念。使用這個概念,我給出更一般化的結論,可以用來有效分析某些圖的 Cartesian product 上的的 star-removing game。使用這些結果,我給出了 r-dimensional grids 的解。

由誘導性多功能幹細胞篩選新生抗原用於大腸直腸癌之抗癌應用

癌症治癒方式成效有限,在iPSC中找出具有潛力的蛋白製成大腸直腸癌疫苗是本研究目的。 實驗先以C57BL/6小鼠之股骨及脛骨骨髓中造血幹細胞分化成為未活化的樹突細胞。放入安慰劑、CpG佐劑、CpG+MC38、CpG+iPSC等抗原物來進行免疫細胞活化測試,流式細胞儀分析結果驗證能否減緩小鼠大腸直腸癌的腫瘤生成。接著,利用質譜儀及大數據分析從iPSC中找出促使樹突細胞活化的抗原物蛋白成分,選出3個候選,透過西方墨點法確認其專一性。查詢候選蛋白TTW1、2、3在The Human Protein Atlas 網站對大腸直腸癌之表現數據。 結果 iPSC的抗原物促使樹突細胞的MHC1標記物活化,助於毒殺性 CD8+T細胞的產生進而透過免疫系統預防大腸直腸癌的產生。TTW1只有在iPSC細胞株表現出專一性,同時資料庫顯示TTW1在大腸直腸癌中具有高表現量。 目前未有文獻探討抗原疫苗的應用,團隊未來專注合成iPSC中TTW1蛋白,進一步開發成大腸直腸癌疫苗。

以仿生袋鼠進行跳躍研究並應用於外骨骼

此研究選擇以袋鼠為仿生對象,希望應用袋鼠高速移動的特點,製作仿生動物,並觀測其跳耀動作,提升動作的流暢度。 首先對澳洲袋鼠在跳躍時的動作,進行動態分析,取得跳躍時其最佳腿部彎曲動作。經歷二次的外觀與整體結構更改,以及數十次的細微尺寸與外觀修飾的調整,完成了此次使用的仿生袋鼠。 此仿生袋鼠使用18公分長的小腿為基準,設計跳躍動作影響便因。首先更改個部位的馬達扭力進行跳躍距離和高度的紀錄,測驗出距離最遠,高度最高的數據,並依同樣的變因條件,進行腿部長度的變更,同樣求得最佳數據再進行下一實驗,以此求得在各變因下最佳的條件。 本研究包含生物觀察、機械繪圖、動作分析,而希望此實驗數據在未來能應用於跳躍型的外骨骼。

液滴爆炸

本研究探討乙醇水溶液液滴於疏水流體表面之分裂現象。此現象可利用揮發造成乙醇之濃度梯度所驅動的表面張力梯度來解釋,此現象又稱為馬倫哥尼效應(Marangoni Effect)。液體為達到最低表面能而改變表面積的普托瑞立不穩定現象(Plateau Rayleigh Instability)也可以做為液滴分裂的解釋之一。 在研究中,研究團隊發現溶液在油面上會隨時間分裂出子液滴,並對於最終子液滴的半徑與分裂現象分別進行定量與定性之探討。本研究於先遣實驗中發現乙醇水溶液濃度之臨界下限為65%~67%重量百分濃度,並以大於(含)此濃度之溶液進行關於乙醇濃度、溶液體積與油層厚度、油層黏度四項參數對於最終子液滴半徑、分裂時間、液滴最大擴散半徑與擴散半徑演變之影響,也針對與參考文獻所選用液體不同深入探討異丙醇與乙醇的蒸發速率的差異如何影響實驗結果。

Discussion for Titanium Peroxides and Their Application for Dealing with Zombie Shrimp Issue

Food safety was an important issue recently. Today sodium percarbonate was used to fake the vitality of shrimps to earn a good sell. However, it may cause harm to health because of the peroxides left over. To handle this problem, we set up two goals to achieve: detecting them and then removing them. In the past, the titration skill was an easy method for determining the concentration of H2O2. It not only spent too much time but also resulted in errors commonly. In this research, titanium sulfate and citric acid were used to prepare the colorimetric reagent. To measure the peroxides in water, several factors were controlled and the SOP for detecting and the calibration line for peroxides finally established. In practical, we turned the colorimetric reagent into the fast test paper which was easily for use. The other part of this research was to clear up the peroxides in water. We use titanium sulfate, hydrogen peroxide and citric acid as starting material via hot-bath method to prepare the nano-photocatalyst of titanium dioxide. Since the powder was inconvenient to deal with large amount of water. The powder-like TiO2 was further made into ball-shaped TiO2 in favor of water treatment and reuse. It was found that the photocatalytic performance of ball-shaped TiO2 was effective to be on duty for removal of the peroxides. In summary, this research provided two techniques to deal with the zombie shrimp. The novel method for synthesis of TiO2 catalyst and the preparation of colorimetric reagent for fast test paper were all in low cost. They had great potential to develop in marketing demand.

Reducibility of Silver ions by the Charcoal: Regarding Mechanisms, Art, and Liquid Waste Management

We elucidated the cause of the phenomenon, in which silver deposits on a bamboo charcoal when the bamboo charcoal is soaked in an AgNO3 water solution. From the experimental results, we considered that the hydrogen which is generated while the bamboo wood is carbonized is chemisorbed as C-H bonds on the surface edge of charcoal (the end of the carbon), and that these hydrogen atoms become hydrogen ions,which then reduce the silver ions and deposit silver. In addition, we created a graph of the mass of deposited silver versus the mass of charcoal, and the graph showed that the mass of deposited silver was strongly correlated with the surface area calculated from the mass of the charcoal. Besides, we showed that charcoal can be used in applications for the treatment of inorganic liquid waste, depositing metals from inorganic liquid waste by bamboo charcoals. Also, the charcoal is used for interior decoration because of its deodorizing effect and beauty. In our study, we create a work of art used silverdeposited charcoal with a motif of Karesansui (Traditional Japanese rock garden).

應用深度學習sequence to sequence model 於古文解譯

以將古文翻譯成白話文為初衷,以爬蟲擷取古文解譯網站「讀古詩詞網」中的大量古文及其白話翻譯作為訓練用的資料,並按照不同文體分開訓練。我們先嘗試用Bert模型做選擇題:給一句古文讓機器從四個選項中選出其翻譯。一開始隨機挑選其餘三個選項,正確率高達96%。因此我們挑戰更困難的設置,撰寫搜尋關鍵字的程式,將有與題目古文相同字的白話文放入選項。雖然準確率有些許降低,但仍高於只選重複字最多選項的結果,代表模型有發展出獨立的判定標準。選擇題成功後,我們用MT5 模型嘗試更困難的翻譯,並在訓練集中新增提供不同前後文的注釋資料幫助訓練。雖然還無法翻得非常準確,但仍在某些句子有不錯的表現。我們也發現了模型對某些特定類型字詞的翻譯有待加強,未來希望透過加強代名詞判斷訓練及持續新增注釋來增加整體翻譯能力。

Studies of spatial self-phase modulation of the laser beam passing through the olive oil

橄欖油含有葉綠素a,葉綠素b,和胡蘿蔔素等高熱吸收率的物質;高斯光束照射橄欖油時,橄欖油吸收的熱量,使橄欖油產生溫度梯度和折射率梯度,並產生熱透鏡(Thermal lens)和自調相(Self-phase modulation)現象。 以雷射光照射盛橄欖油水平置放的方型盒時,中央軸的照度最大,橄欖油的溫度最高,折射率和密度最小。由於對流作用的影響,使得光束照射到的橄欖油的上半部折射率梯度小於下半部;光束通過橄欖油後,在屏幕上出現的繞射圖樣呈現上半部的亮帶半徑小於下半部。 將橄欖油改置圓柱筒中,雷射光由上向下照射,可以消除熱對流現象。用不同功率的雷射,照射不同液柱高度,和不同熱吸收率的橄欖油;探討功率、液柱高度、和熱吸收率對:繞射亮帶最大半徑、繞射亮帶半徑隨時間的變化、和亮帶數目的影響。