ConalepAsistant
Throughout our generations, a traditional system has been implemented for registering student attendance, in which the teacher is responsible for carrying out said activity, investing an average time of 15 to 20 minutes, which are part of the time of class. The objective of this project is to optimize this process, thus achieving effective class times, promoting the use of digital tools and innovation in teaching practice, in addition to generating security and confidence in tutors through the use of a service of message, which will notify the student's attendance in real time. Through a survey of the teaching staff of the CONALEP 338 Córdoba campus, it was detected that each teacher has academic loads equivalent to 3 to 5 modules per day, with an average of more than 40 students assigned to each module. Based on this information, the use of technological tools will be promoted and this process of teaching practice will be innovated with zero costs.
In silico Screening of Forty Antiviral Phytochemicals as Inhibitors to the Envelope Protein of Dengue Virus Serotype 2 (DENV-2)
Infections by the Dengue virus (DENV) cause a disease amonghumansreferred to as Dengue fever, which causes thousands of fatalities globally. There is no existing treatment as of yet that successfully targets DENV. Among the factors thatdeterminetheentry of the virus and severity of the disease is the envelope(E) protein of DENV. This study aimed to examine forty antiviral phytochemicals enumeratedinpaststudiesaspossibleinhibitorstotheEprotein of DENV to provide candidates to aid in drug discovery against DENV. The phytochemicals were screened for their likelihood of inhibition of the E protein using AutoDock Suite and LigPlot+. Seven phytochemicals produced favorable binding affinities to the E protein, which are based on the interactions between the phytochemicals and amino acidsintheactivesiteoftheEprotein.Lipinski’s rule of 5 was then used to screen the seven phytochemicals for oral bioavailability. Glabridin has a binding affinity of -7.6 kcal/mol and was predicted to be orally bioavailable. This phytochemical interacts with amino acids in the E protein active site through hydrogen bonds to Asn355, andPhe337, as well as ten hydrophobic interactions. These interactions ensure that glabridin is able to specifically target and fit intotheactivesiteoftheEprotein, preventing its binding to the host cell and activating its viral proliferation. Glabridin is known to be found in the roots of licorice plants, providing anatural source for a possible cure for Dengue fever.
Development of Oil Collecting Submarine using AI and hydrophobic solution
Such as the plastic waste and industrial discharge that permeate our oceans, it is the insidious and infamous nature of oil spills that demands our immediate attention. These spills, with their far-reaching ecological ramifications, pose a profound danger to our marine ecosystems, demanding urgent action and a heightened awareness of the true menace that is caused by this oil
In Silico Carotenoid Compound with Protein in Durian (Durio zibethinus Murr.) Seed Waste and Hedonic Test Innovation in Making Healthy Cereal Organic (HCO) (Nutrient-rich Functional Food Alternative)
Durians’ seeds have potential as a food source due to their content and nutrients. Durians’ seeds contain fiber, minerals, vitamins A, B1, B2, C, carbohydrates, folate, potassium and copper. Nutrients are needed for the body's health and growth and development process. Durians’ seeds have the potential as a nutrient-rich food alternative. Researchers made an innovation in the form of cereal, Healthy Cereal Organic (HCO). Analysis of durians’ seed content through two stages. First, wet lab examination and second, in silico method. The wet lab examination shows the results that durians’ seeds contain 10.17 Kcal of fat energy, 4.09% ash content, 11.25% water content, 72.79% carbohydrates, 1.13% total fat and 10.74% protein and the in silico method shows the content of carotenoid compounds (vitamin A, quercetin, beta-carotene, zeaxanthin) as a drug delivery system which means that this compound is able to be absorbed by the body with the help of albumin as a carrier that maintains stability and increases its activity. Feasibility analysis based on toxicity tests, Durians’ seed compounds show inactive (non-toxic) results. Allergenicity test showed non-allergen durians’ seed content. Hedonic test was conducted on 20 panelists dominant to the HCO1 sample for aroma by 60%, texture 90%, taste 40%. It can be concluded that durians’seeds can be used as a basic ingredient for making nutrient-rich Healthy Cereal Organic (HCO).