本研究將以BiOCl、BiOBr以及Pd/BiOCl的晶體製備二氧化碳還原之光觸媒，用以還原二氧化碳，期許能製造出具有經濟價值的還原產物，以緩解全球暖化並利用可再生能源。此外，我們藉由探討此類晶體在二氧化碳還原中的差異，比較加入不同鹵族元素及是否摻入鈀金屬對於光催化還原二氧化碳效率及產物的影響。 合成晶體後，我們透過X射線衍射儀(XRD)、掃描式電子顯微鏡(SEM)、能量散射X射線譜(EDX)進行晶體的鑑定，也確定Pd/BiOCl的晶體結構是以BiOCl為主體，且Pd鑲嵌在其表面。我們也以X光光電子能譜儀(XPS)了解晶體的鍵結型態及推測不同晶體表面的OVs相對含量，並以紫外光/可見光光譜儀(UV-vis)檢測樣品的能隙，推測其光催化性能。 我們發現摻入鈀的BiOCl晶體結構為分散的片狀結構，是三種晶體中唯一的奈米晶體，且能隙為三者中最小(2.46eV)、表面OVs含量也增加；表面附著的Pd奈米金屬顆粒更可以協助主催化劑的電子-電洞對維持分離狀態，促進其光催化效率。 最後我們將合成的BiOCl、BiOBr以及Pd/BiOCl晶體應用於光催化還原二氧化碳，並以氣相層析熱導偵測器(GC-TCD)及氣相層析質譜儀(GC-MS)檢測產物種類及產率，發現還原出的氣體產物有H2、CO、CH4。而總還原產物及含碳還原產物的產率皆以Pd/BiOCl為最高。

在程式專案開發中，偵測錯誤常為最耗時的環節，進而影響整個專案的開發時長。而現今雖有些許輔助開發者提升偵錯效能的工具，但這些工具也只能藉由提供編譯執行中的資訊讓開發者省去偵錯時的繁瑣步驟，仍須開發者自行評估每段程式碼的正確性。此研究透過程式段落分析與資訊檢索實現自動錯誤定位，在每個程式段落標記其成為臭蟲（bug）的可能性。在程式段落分析中，執行使用者之原始碼，並透過歸納最終結果為正確及錯誤之執行路徑差異分析出每個程式段落的可疑性。接著運用資訊檢索技術於資料庫中找尋相似之原始碼，並參考其偵錯結果優化現有之可疑性，形成最終之可疑性排名。此研究不只結合了上述兩種技術，更優化可疑程度之計算方法以及資訊檢索中的相似度比對機制，達到更完善的錯誤定位。（此指「臭蟲」非語法錯誤（Syntax Errors），而為邏輯錯誤（Logic Errors）。）

The number of natural disasters has risen significantly in recent years, and with climate change there is no end in sight. Consequently, the demands on rescue forces around the world are increasing. For this reason, I asked myself what I can do to improve the work of rescue teams. Advances in artificial intelligence and drone technology enable new possibilities for problem solving. Based on the technological advances mentioned above, an autonomous Search and Rescue drone was developed as part of this project. The system assists rescue workers in searching for survivors of natural disasters or missing people. This paper also suggests a method for prioritizing survivors based on their vitality. The system was implemented using a commercial Parrot ANAFI drone and Python. The software was tested on a simulated drone. To simplify the development, the whole system was divided into the following subsystems: Navigation System, Search System and Mission Abort System. These subsystems were tested independently. The testing of solutions and new concepts were performed using smaller test programs on the simulated drone and finally on the physical drone. The Search and Rescue system was successfully developed. The person detection system can detect humans and distinguish them from the environment. Furthermore, based on the movements of a person, the system can distinguish whether the person is a rescuer or a victim. In addition, an area to be flown over can be defined. If something goes wrong during the mission, the mission can be aborted by the Mission Abort System. In the simulation, the predefined area can successfully be flown over. Unfortunately, controlling the physical drone does not work. It stops in the air after takeoff due to the firmware of the drone. It does not change the flight state of the drone, which results in all subsequent commands from the system being ignored. This paper shows that artificial intelligence and drone technologies can be combined to deliver better rescue services. The same system can be applied to other applications.

QR Code是由黑白模組組成的二維數位條碼，掃描後可讀取儲存的訊息。受限於設計原理，QR Code使用二進位制儲存資料。增加模組數目可增加資料量，但若在條碼內塞進太多模組時，尺寸太小的模組將無法被掃描器讀取。此外，目前QR Code掃描器僅支援單張掃描，並無法應付同時多張條碼掃描的實務需求。 如能克服顏色辨識，理論上彩色二維條碼將能克服現行QR Code的限制，但市面上並無相關產品可供測試。因此本專題設計了一款10×10、具8顏色的"Colour Matrix"，並利用Raspberry Pi開發Colour Matrix在手持裝置上運作的軟硬體來進行實驗。此實驗成功利用機器學習演算法在Raspberry Pi上進行的顏色辨識。開發的程式在單張掃描上效能與使用pyzbar辨識QR Code相當；在多張掃描方面，使用pyzbar辨識QR Code的解碼成功率為3.1%，而本專題的方法將成功率提升至92.4%，擴增數位條碼的使用範圍，具商用價值。

Inhibitory effects of the secondary metabolite of actinomycete were examined on cell cycle of the yeasts of S. pombe and S. cerevisiae. The secondary metabolite was obtained from cultivation of the actinomycete isolated from the soil of Owakudani in Hakone, Japan. The fifth fraction of the secondary metabolite by ODS column separation (HK-T5), which was soluble to pure methanol, was used in the present experiments. The HK-T5 brought about the delay of forming colonies of S. pombe for about 11 days compared to that cultivated without the HK-T5. The delay of the colony formation was longer for the S. pombe cultivated with more amount of the HK-T5. The cultivation with HK-T5 also brought about the extension of the lifespan of the S. pombe for more than 10 weeks in a liquidus medium. The cell life recovered the ordinary manner by removal of the HK-T5, meaning that the activities of the HK-T5 is reversible. These facts confirm the suppression of cell cycle, and the delay of cell growth by the HK-T5. These phenomena were similarly observed for S. cerevisiae. Comparison of the action of HK-T5 with hydroxyurea, which is an anticancer drug inhibiting the cell cycle at S phase, clarified that the inhibitory action of HK-T5 worked at the phase earlier than S phase. The combined effects of HK-T5 on the cell cycle were evaluated with triamcinolone acetonide (TA), or aspirin, the former of which is a drug synchronizing cancer cells in S phase, and the latter keeping human cells in G1/G0 phases. The combined use of HK-T5 with TA synchronized the cells at the phase slightly proceeding from G1 to S phase without toxicity. On the other hand, the combined use with aspirin made the inhibitory effect of HK-T5 inactive. Hence, the HK-T5 is attractive as a drug for the extension of cell lifespan, and anticancer therapy.

蚊蟲呼吸透過氣管系統，本研究假設底棲孑孓與搖蚊幼蟲具備血紅蛋白系統以擷取氧氣。戶外採集8種孑孓和1種搖蚊幼蟲，錄影觀察白腹叢蚊、竹生翠蚊和鹽埕搖蚊幼蟲長時間停留底層；家蚊、斑蚊則反覆上下至水面呼吸。顯微鏡下發現白腹叢蚊幼蟲體壁內側充滿紅點，色澤隨著富氧或缺氧而變化；然二種斑蚊則不明顯。PCR增殖6種蚊蟲和1種搖蚊血紅蛋白基因片段並建構親緣關係樹。定量RT-PCR顯示，白腹叢蚊與鹽埕搖蚊在缺氧條件下，血紅蛋白相對表現量分別增加5倍和150倍，上層埃及斑蚊和白線斑蚊則增加3.9倍和1.5倍。西方墨點法證實孑孓缺氧條件下，17-kDa血紅蛋白皆有大量表現。本研究首次確定6種蚊蟲具血紅蛋白基因，證明孑孓血紅蛋白基因在缺氧下的表現量增加，包括mRNA與蛋白質。此等反應氣候變遷，暖化導致水溫升高與低溶氧條件下，蚊蟲可能有因應環境改變的呼吸機制。未來將進一步標幟血紅蛋白在蚊幼蟲體內組織之表現與其他環境變因之影響。

The aim of this research was to investigate whether the ecology and biology of the Orange River mudfish Labeo capensis were suitable for the species to be used in fisheries. Three fleets of the gill nets were set, parallel to the shore. One fleet was lifted, and the fish were collected by hand. The two remaining fleets were lifted the next day. The seine net was pulled for 10 metres within the littoral zone. The net was then pulled towards the shore of the dam and the procedure was repeated four times. The four fyke nets were set parallel to the shore and were left for two nettings nights and then lifted. All fish caught were collected by hand and placed into buckets. The majority (82.93%) of the fish caught were within the 0-100 mm size class. The 101-200mm and 201-300mm size classes contain similar numbers of fish, while no fish were caught in the 301-400mm size class. The hypothesis was accepted. Allemanskraal Dam, as of the study period, has a very small juvenile fish population of L. capensis, as only 7 out of 41 fish individuals caught were within the 101- 300mm fork length size class. These results show that the population of L. capensis is not established as of yet, as the research did was right after their breeding season. Historical research has shown that sexually mature individuals of the L. capensis species tend to be a minimum of 300mm SL, 4-6 years after hatching. The population was largely young-of-the-year and may develop into an established population in 3-4 years (after sexual maturity). The L. capensis population in Allemanskraal Dam has the potential to be a fishery species if suitable conditions are maintained. Establishing this species’ potential will therefore allow economically viable fisheries to utilise them sustainably and to their full economic potential.

在這個資訊發達的時代，網路充滿著五花八門的資訊，導致我們在查詢資料時會因為這些雜亂且未經過濾的資料浪費許多時間，其中最為氾濫的便是點擊誘餌（clickbait），此種新聞常常有著吸引人的標題，而內容卻不會與主題相符，人們也常常在讀完整篇文章後才意識到自己浪費了許多時間在無意義的資訊上面。解決此問題很常用的方法之一便是運用摘要演算法來讓讀者先對新聞有一個大概的理解，不過，雖然摘要演算法越來越普及，但產生出來的摘要仍會和人為判斷的結果有所差距，進而造成閱讀理解上的錯誤以及偏差，所以我們想要藉由這次研究，從一個嶄新的角度切入，探討摘要演算法和句型分析之間的關係，融合原本向量建構的方式以及語句結構的分析來測試摘要的準確度，並且由結果研發出一個可以產生出更為精確的主旨之摘要演算法，除此之外，我們也會融合實地調查以及搜集意見的方式來更進一步探討人們思模式與產生出的摘要之關聯性。

本研究針對學習圖論演算法的需求，設計一套使用者友善的繪圖軟體Graphene。Graphene繪圖程式除了提供高可讀性的繪製結果，作為輔助繪圖的工具外，也可直接輸入競賽題目的文字格式測試資料產生繪圖結果，並結合現有繪圖演算法，改善、優化樹與類樹圖的繪製結果。此外，也加入時間軸、自訂外觀、參數調整、匯出圖片等功能，幫助學習者理解圖論演算法，亦可幫助教師製作教材，有助於圖論演算法教學。 Graphene採用的繪圖演算法以force-directed graph drawing演算法為基礎，實作節點的分布。然而初始的節點分布會影響繪圖結果，因此我們利用biconnected component、block-cut tree等圖論結構對圖的繪製進行優化。首先找出圖的biconnected component及關節點，重新定義block-cut tree裡的block，接著利用radial tree的布局方式配置每個block，再套用force-directed graph drawing演算法，得到最後的布局結果。如此可以減少不同block之間的交錯，得到較佳的結果。

Currently, no method can completely eliminate the human immunodeficiency virus (HIV) in an infected person. HIV employs an accessory protein called Nef that forms a complex with cellular AP-1, preventing detection of HIV-infected cells. Lovastatin has been recently identified to inhibit the formation of said Nef-AP-1 complex, but its effective concentration is remarked to be far higher than other Nef inhibitors. This study aims to develop a modified lovastatin molecule exhibiting higher binding affinity to the HIV-1 Nef protein than lovastatin in silico. Modified lovastatin molecules based on the interaction map of lovastatin with Nef were modeled, and flexible ligand-flexible receptor docking to the Nef binding site was performed using AutoDock Vina. Residues within the Nef binding site identified by Liu et al. (2019) to be crucial (Glu-63, Val-66, Phe-68, Asp-108, Leu-112, Tyr-115) were set as flexible. Fragment-based drug design was utilized to append molecular fragments to lovastatin in order to maximize its interactions with said crucial residues. From the fragment-based approach, molecule F4 ((1S,3S)‐8‐{2‐[(2R,4R)‐4‐chloro‐6‐oxooxan‐2‐yl]ethyl}‐3‐(hydroxymethyl)‐7‐methyl‐1,2,3,4‐tetrahydronaphthalen‐1‐yl 4‐aminobenzoate) exhibited a binding affinity of -9.0 kcal/mole, and its estimated IC50 ranges between 0.25-0.51 μM which is at least 7.5 times lower than the reported IC50 of lovastatin from literature. This study presents insights on the key modifications to improve lovastatin as an HIV-1 Nef inhibitor and pertinent information about the Nef binding site for future drug development studies.