Effect of Air Resonance by Wind Speed Difference on Falling fruit
This study completes an air vibration equation expressed wind speed slope and wind speed. First, preliminary experiments identified air vibrations when wind speed differences occurred over distance. Several air fans were connected in series and the rotational speed of the air fan was adjusted to vary the wind speed with distance. At this time, only certain pendulum oscillates during a particular wind speed slope. It was expected that the pendulum would shake because the frequency of the air due to the slope of the wind speed was equal to the natural frequency of the pendulum. In addition, relatively short pendulum swings in large wind speed slope, long pendulum swings in short wind speed slope. After calculating the natural frequency of the seasonal growth of fruit using the physical factors model, we experiment how resonant frequency was related with cone length, angular width, wind speed, velocity and secondary derivative. the actual experiment analyzed the natural frequency of the fruit and resonance from the air vibration as the linear function of the wind speed, velocity, and secondary derivative. The experiment determined that the pendulum of a specified number of frequencies resonated with a particular wind speed pattern. It is judged that the vibration of air is related to first derivative of wind speed depending on speed and distance. However, it is very difficult to express the flow of nonlinear fluids as a function of simple function, particularly the effects of air vibrations caused by wind speed second derivative, which appeared to be associated with forces. This is a task that needs to be solved through further research.
探討抗憂鬱症藥物phenelzine對於發生在小鼠巨噬細胞中的細胞凋亡所產生的保護作用及機制
之前有研究指出,使用一些單胺氧化酶(monoamine oxidase, MAO)的抑制劑如pargyline和clorgyline,皆可以保護serum starvation所導致的細胞凋亡,表示MAO可能在細胞凋亡的路徑中扮演重要的角色。 本研究著重於一個臨床上被拿來當抗憂鬱症藥物的MAO抑制劑苯乙肼(phenelzine, PZE)對於沿著腫瘤壞死因子-α (tumor necrosis factor-α, TNF-α)途徑而產生細胞凋亡的小鼠骨髓巨噬細胞(bone marrow-derived macrophages, BMDM)所產生的保護作用。 本研究的結果顯示PZE的確可以保護循TNF-α途徑死亡的細胞,同時使活性氧化物質(reactive oxygen species, ROS)的量下降。我們推論造成此現象的原因是PZE藉由抑制MAO,使得ROS的量下降,進而保護細胞。