全國中小學科展

三等獎

「孓」戰關鍵―台灣淡水渦蟲捕食蚊幼蟲機制及其黏液探討

虎紋三角渦蟲(Girardia tigrina)是台灣本土常見的渦蟲,常用於再生之研究。然而其黏液功能與成分以及捕食蚊幼蟲機制皆尚未清楚。本研究中,從解剖顯微鏡觀察得知渦蟲爬行時分泌的黏液能將蚊幼蟲纏住,且發現渦蟲偏好從蚊幼蟲腹部末端及肛進行攻擊,並於體外行物理機制初步消化後,將蚊幼蟲組織以咽運動產生的負壓吸入體內,再行化學分解。以Congo Red、CBR250及PAS染色,發現渦蟲黏液中具有多醣、蛋白質及醣蛋白,以SDS-PAGE分離渦蟲黏液蛋白後,用銀染法分析發現渦蟲黏液包含多種蛋白質,主要為蛋白質單體15kDa,以蛋白質N端定序及LC MS/MS交叉比對分析得知渦蟲黏液中可能含有titin、calcium-binding protein等蛋白質,相關實驗還在進行中。我們也發現渦蟲在有無蚊幼蟲環境不影響其黏液蛋白分泌量,然而黏液蛋白成分組成是否有差異,需再繼續研究。本研究結果可能對應用生物防治法抑制病媒蚊有所助益。

Remedies Recovered from Roof Top Resources

Moss from a roof top was used to treat ear infections in my grandfather’s village. This remedy sparked my curiosity and so I began researching. I was bewildered to discover that the resistance to antibiotics has been labelled as a “Catastrophic Threat” and has been ranked in the same category as terrorism and climate change. Governments globally are urging scientists to identify and produce new antibiotics and reassess novel approaches1. This project aims to evaluate two objectives through the use of several integrated technologies and modified methods: (a) To determine if the extracts, solutions and raw materials derived from Heart wood portion of Picea glauca, Populus tremuloides, Salix spp, Betula papyrifera, Pinus contorta, Quercus alba, Thuja occidentalis, Climacium dendroides, Dicranum fuscescens and Kieselgur, will inhibit the growth of Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes, and Escherichia coli. (b) To scientifically reassess my grandfather’s traditional method of treating ear infections using roof moss. The Heartwood portion of each tree was removed using a hammer and mallet. The Heartwood was then burnt to derive the ash and a miter saw was used to make sawdust. The moss was collected, dried and labelled. A Methanol Extraction was performed on all saw dust samples and moss using a Soxhlet Extractor for 24 hours. The ash solutions were diluted, filtered, and neutralized to pH 7. The solvents were evaporated in a Rotary evaporator and the residual material was stored in round bottom flasks. The Kirby Bauer method was modified and a Well Infusion method was devised for the biological assay. The Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes, and Escherichia coli were plated using a 0.5 McFarland Standard. Paper filter discs containing 20uL of each extract solution and raw material were precisely placed onto the inoculated plates and incubated for 24 hours. The preliminary results were initially unfavourable, as data could only be collected and analysed for one species; Thuja occidentalis (White Cedar). However, these results were extremely encouraging when the zones of inhibition were measured and analyzed. Confidence Intervals were calculated at 95% and the T-Tests were calculated at a 0.05 alpha level, which indicated significance when compared to the control. The Chi Square values were greater than the critical value of 7.8 and therefore the thorough statistical analysis indicates that the results were not due to chance alone. Literature has indicated that certain components of trees do indeed have antibacterial properties, however there is very limited research specific to the Heartwood portion. Furthermore, I discovered that the Heartwood portion of the White Cedar tree does have certain antibacterial properties that definitely justify further testing. In addition, a combination of examining my grandfather’s possessions and analyzing present data, I can confidently support my grandfather’s traditional method. In conclusion, the use of the Heartwood portion of the White Cedar to combat bacterial infection warrants further exploration. Remedies Recovered from Roof Top Resources may be the solution to this catastrophic threat.

The expansion of ticks in the valley of Poschiavo: a growing threat to the future?

In recent years, the ticks have reached the valley of Poschiavo and so far no study has been done to determine their diffusion. Recently, this presence has become a much discussed topic as these ticks can be carriers of pathogenes and represent a danger to humans. The goal of this work is to analyze the current situation in the valley of Poschiavo to understand in which areas the ticks are widespread, if they are carriers of pathogens and which factors could have an influence on their expansion. Several methods have been used for data collection. Ticks were found on ungulates killed during the high hunt in autumn 2016. In spring 2017, ticks were collected in various areas of the valley using the flag method that involves dragging a cotton cloth onto the ground. Some of the collected ticks were sent to a laboratory to identify the presence of the Borrelia burgdorferi, the pathogen responsible for Lyme borreliosis. To understand the evolution of the presence of ticks in the valley, the doctors and veterinarians were interviewed. Finally, to identify any climate changes related to the diffusion of ticks, the evolution of the tem-perature and relative humidity measured by two meteorological stations in the valley of Poschiavo since 1980 have been analyzed. Thanks to this study it was possible to highlight for the first time the presence in the valley of Poschiavo of ticks wich are bearer of the Borrelia burgdorferi. In fact, the bacterium was present in 26% of the analyzed ticks. Currently, the thicks populate the southern part of the valley, from the lake of Poschiavo to Campocologno, a small area in the central part of the valley and the area around Poschiavo and San Carlo. The interviews carried out showed that in recent years the ticks in the valley have increased and that the climate change could be a possible cause. In fact, since 1980 the temperature measured on the bottom of the valley has increased on average by 1.5 ° C and also the relative humidity has risen slightly. These changes could affect the diffusion of ticks in the valley of Poschiavo. In the future the temperatures will rise further and consequently the climate of the Poschiavo valley will most likely be more suited to the life of the ticks favoring their in-crease.

故態復「蒙」,「日」新月異-Monge's theorem的性質探討與推廣

本研究以蒙日定理「平面上三圓彼此的外公切線交點共線」及其對偶定理「平面上三圓彼此的內公切線交點與另一圓的圓心的連線共點」出發,探討三圓更多由內、外公切線所產生的共點共線性質,進而探討四圓以上的情形,以及正多邊形、圓錐曲線等位似圖形,並推廣至空間中的球體。正如本研究作品名稱,我們將鮮少人研究的蒙日定理萌發出新枝,在日夜中茁壯,甚至最後有驚人的發現「在空間中n個外離的球,任意1個球的球心與另n-1個球的蒙日點連線會共交一點,此點稱之為n球的蒙日點」,此「點」發現,讓人不禁對宇宙中星體之間的關係產生更多無限的想像。

IMPACT OF FIRE WOOD COLLECTION ON WEATHER AND CLIMATE OF JIRDIN VILLAGE

Climate is the average weather in a place over a long period. The changes in climate may be due to natural forces or from human activities. There is growing concern among the scientific community regarding climate change. Biodiversity, forest, monsoons, weather are now at risk due to climate change. Today climate change is happening at an increasing rapid rate. One of the causes is deforestation. Firewood collection in one of the major means the felling of trees. Excessive emission of CO2 by burning, which is a green house gas, responsible for increasing the temperature and causing drastic climate change. Hence, to know the impact of firewood collection in drastic climate change we have undertaken a project entitled, “Impact of firewood collection on weather and climate of Jirdin village.”

對弈機器人運用於預防及延緩失智症之研究

本研究目標在於改良對弈機械人及分析長期對弈資訊,運用於早期老人失智症之預防。 據文獻及詢問專家後得知對弈遊戲具有預防失智症狀的功效,而研究中的對弈機器人以大腦功能狀態評估(JOMAC)為研究方向,研究資料分析如「玩家思考時間、對弈棄局次數、下錯頻率」等資訊並設計檢測橋段等機制以符合評估項目達到預防提醒之目的。對弈人工智慧,針對玩家棋力會自動調整機器人的棋力。採用 UCT 演算法,透過搜尋模擬能計算出各點落子勝率,藉由選擇較高或較低勝率的落子點,使人工智慧棋力與使用者旗鼓相當,保持使用者遊戲體驗及強化思考使失智症狀得以延緩。此外運用類神經網路改良影像自動校正,利用學習的方式解決不穩定環境光下誤判過多的問題,且提高校正速度,使對弈過程更加穩定。

缺幾格大不同-從方格排列結構到路徑之探討

本研究探討將方格填入Young Diagram之排列結構,考慮填入的順序並計算其方法數。已知Hool Length公式得以計算特定形狀的Young Tableau方法數,而本研究欲討論在給定各相連方格形式與其數量的情形下,一般化的排列圖形之性質及數量關係。首先發現骨牌的排列與「缺一格」形式之數量相同,進而深入觀察排列的結構以尋找兩者間的關聯性,並藉此對應關係(bijective relations)解釋這個特別的現象。接著,進一步的利用路徑表現此結構的相關性質,嘗試探討一般化的缺格情形,藉由路徑的對應,得知該排列方法數均為「廣義Motzkin數列」的線性組合。除此之外,更擴展至廣義的r-Ribbons「多格相連」的排列結構,發現r-Ribbons方格排列圖形在完整與「缺一格」的情況下可一一對應,若將n個r-Ribbons填入高度為H的Young Diagram中,當H不超過r時,其總方法數為Hn,以各列編號相異的方格數量進行分類,其結果為在H為空間下的Pascal分佈。

乾坤大挪移

會議室圓桌上有n個座位,順時針依序放有編號①、②、③、 、n,共n張名牌。將參與這場會議的人也編碼,依序為1、2、3、 、 ,假設編號1的人一定會先抵達並坐到了名牌②的位置,剩下的人則依亂序到來,先找到自己名牌的座位,如果位置是空的就坐下,如果位置被佔了就往順時針方向找到下一個空位坐下(例如3到達時,若③、④均被坐了,而⑤位置是空的,則3就坐到名牌⑤的位置)。等到一個人坐定後,另一個人再進入會議室,依此規則,最後此n人到底會有幾種不同的坐法? 我們以遞迴手法以外的方法解決了這個的問題,並深入探討: 1.能否從入座的順序立刻得知最後坐定的位置? 2. 能否從最後坐定的位置,找出進入會議室的順序?同時得知有幾種不同進入會議室的順序會符合同一種坐法? 3. 每個人坐錯位置的機率為何?恰k人坐錯位置的機率為何?坐錯位置人數的期望值為何?

翻轉塗色

長度為n的字串,我們設計了對偶塗色,目的在減少同色字串出現的周期規律。而計算這樣的字串中存在多少同色的3-AP。 利用對偶塗色字串的特殊對稱性質,我們先將其中的同色3-AP分成單獨由字串前半2n-1形成的第I類同色3-AP及部分在前半2n-1部分在後半2n-1的第II類同色3-AP,並以d-中心排列方式重新排列,將第II類同色3-AP分解成較小的子結構,得到遞迴式計算跨越中心的同色3-AP,而得到定理1,計算第II類同色3-AP的數量。 由對偶特性得知,2倍的第I類與2倍的第II類同色3-AP即為長度2n字串中同色3-AP的總個數,由此推出定理2: n階對偶塗色字串中(字串長度2n)的同色3-AP總數為1/16N2-1/12Nlog2N+5/36N,N=2n. 此結果與所有塗色方式中平均存在的3-AP數量相近,第二大項-1/12Nlog2N則與對數值log2N相關。 有趣的是,經由程式計算的結果發現,對偶塗色法中同色4-AP、5-AP的數 量也似乎是平均值。甚至從任給定的字串開始作對偶複合字串,程式計算的結果也是接近平均值。

同類相食行為的新發現

同類相食行為廣泛發生於動物界,兩種可能原因:個體的特殊營養需求和族群的汰弱留強策略。觀察雜食性的高音符絲鱉甲蝸牛(Macrochlamys hippocastaneum),初步發現同類相食行為與蝸殼破裂與否有關,殼完整的個體間不會發生相食行為(100%),且當破殼程度愈大愈易發生。食性實驗中攝取過植物性養分的個體傾向選擇同類相食(χ2=22.04,***P<0.001),同時提供同、異類蝸牛內臟時則未顯著選擇同類(χ2=3.76, P=0.053),因此未能充分支持特殊營養需求。然而,此種蝸牛會追蹤破殼同類分泌之特殊黏液且具顯著趨向性(χ2=13.06, ***P<0.001),與距離呈負相關(χ2=6.53, *P<0.05)。觀察腹足顯微構造中,發現內有特殊的疏鬆組織與大量分泌細胞,且通往尾端分泌特殊黏液的開口部位。結果證實破殼受傷個體產生的特殊黏液會主動引起同類相食,支持汰弱留強的族群策略,且物質誘發同類相食模式為動物行為研究中首次發現。