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EmerApp+: An innovative application for personal security

EmerApp+ is software designed for intelligent devices as a personal security database manager. In case of emergencies, it is an application which integrates location, tracking, and communication tools. It is triangulated between a database to a communication server as well as a second which is NASA server that offers climate and seismic information for Mexico. This application has two sources of communication, SMS messages and a newly created social network. In case of natural disasters, an extension for drones has been developed for this application, enabling rescue teams to delimit the land boundary where the disaster struck. In order to speed up the search and rescue operations a triangulation of network-drone- smartphone is completed.

新興汙染物銦對阿拉伯芥生長之影響 Physiological and Molecular Response of Arabidopsis thaliana to Indium Exposure

銦之化合物常被應用於半導體產業當中,隨著使用量的增加也提高銦污染流佈於環境的風險,若此污染物流布至土壤並累積於植物體內,則可能通過食物鏈而影響人體的健康。現今國內外鮮少有銦對植物影響的相關研究,因此本研究以培養基試驗,探討銦對模式植物阿拉伯芥生長之影響。結果顯示,當銦處理濃度為500 µM時,其生質量以及根長會受到抑制。MDA含量的增加,顯示銦會對阿拉伯芥造成氧化逆境,而穀胱甘肽與金屬螯合素並非阿拉伯芥在銦逆境下主要的抗氧化機制。本研究亦發現銦處理下會影響對錳、鉀、鈉、磷、鐵、錳、銅以及鋅的吸收。此外,X光吸收光譜分析顯示根部以及地上部中銦物種有明顯組成上的差異。於根部有42.9%的銦是以吸附於細胞壁的形式存在,這可視為植物對重金屬所採取「隔離」策略的防禦方式之一。

費馬多邊形數定理之延伸探討

本研究旨在研究費馬多邊形數定理(任意非負整數必可表成k個k邊形數的和)的一般化情況,也就是說,任意非負整數是否能表成給定的二次多項式數列中所選取的γ項和。以數學模型敘述,就是探討對一個已知的二次多項式an2+bn+c,是否可找到一正整數γ,滿足∀x∈N∪{0},∃α1,α2,…αγ,使得x=∑γi=1(aαi2+bαi+c)。 本作品主要探討若此探究模型存在,那麼數列〈an 〉的一般式an2+bn+c與γ值之間會存在什麼關係,並期望能運用一個簡潔明瞭又一般化的數學式表示。本文亦提供另一個數學模型,探討γ值與某些特殊係數a,b,c之間的關聯性。而本文探尋[a/2]n2+[b/2]n+1,a∈N,b∈Z,a+b≡0(mod 2)(此為本文主要探討的二次式),求得此二次式所對應之γ值的方法為先令p=[2a/(a+b)]+2,再藉由所建立的模型二,求出[(p-2)/2] n2+[(4-p)/2] n的γ值,接著再用所建立的模型一來求得[a/2]n2+[b/2]n+1的γ值,進而依循此方法最後得出任意形如[a/2]n2+[b/2]n+1的二次式之γ值。

Fig Preservation

Figs have become an expanding industry here in New Zealand and are a current export fruit which could potentially provide a large amount of profit to both growers and the New Zealand market as a whole. Nicola’s family has about 10 acres of fig trees. They sell the figs locally and as an export. They generally sell for about $13 per kilogram here in New Zealand and $26 in the USA. However, figs only have a shelf life of about 7 days. This is because at present there is no proven pre or post-harvest treatment or method of storage that helps to decrease the rate of decay of the fig fruit. After researching post-harvest treatments for figs, Nicola found a report which claimed to have developed treatments that increased the shelf life of figs by about 5 weeks. With this kind of increase, it would be possible to transport, store and export figs over longer periods of time without running the risk of losing large amounts of produce, or delivering unsatisfactory fruit to customers. Nicola developed 7 different post-harvest treatments based on the ones that had shown promise in earlier research. These were hot-water baths of different temperatures, both with and without different bleach concentrations. To test these on the fruit she set up four experiments – a dry matter test, a firmness test (using a penetrometer), a colour test and observation of detrimental features of the fig. She tested these treatments at 0, 7, 14, 21 and 28 days from harvest. Nicola found that after 7 days, the firmness of all of the figs that had been treated had decreased to a large degree. The only figs that did not have a massive decrease were the untreated fruit. However after about 14 days, the firmness of all of the fruit became about the same and after this 14 day mark, she would not have considered any of the figs to be edible. However, in the appearance tests, it seemed that the treated figs that had the least amount of mould and rot were the ones that had been treated with higher levels of bleach such as the 55 degree Celsius water bath with 0.003L of bleach to every litre of water, and the 35 degree Celsius water bath with the same concentration of bleach. Overall, Nicola’s results showed that the hot water bath, and hot water bath and bleach post-harvest treatments did not slow the decay of the fruit in the earlier weeks after picking. In effect, Nicola’s research showed that the information she had relied on to help plan her study had claimed too much and that the treatments were less effective than had been stated. More research will be needed to find a more reliable way to improve the shelf life of figs.

探討CID384634合併臨床賀爾蒙治療用藥tamoxifen對三陰性乳癌的作用機轉

乳癌是台灣女性死因第四名,其中的三陰性乳癌因具備高轉移力,又缺乏特定受體而不適用於標靶藥物治療或賀爾蒙治療法,所以其治療方法有其困難度。CID384634為2-phenynaphthyridone(2-PN)的衍生物,此藥物可藉由干擾微管蛋白聚合抑制致瘤性高的細胞株生長,於是我們想探討CID384634對於高度轉移性的三陰性乳癌是否也有同樣的治療效果。本研究以MTT assay和西方墨點法探討其治療效果與作用途徑,並發現CID384634可藉由回復雌激素受體表現,並且在合併臨床賀爾蒙治療用藥tamoxifen有明顯抑制三陰性乳癌細胞存活率。實驗也證實CID384634具有抑制上皮細胞及間質細胞轉換的作用。我們希望在不久的將來CID384634可以用來治療三陰性乳癌。

英文篇章難易度自動分級之研究

以製作適合高中生的英文篇章難易度自動分級為初衷,本研究採高中英文課文為語料,針對「如何分級」,意即從文章萃取哪些特徵、利用何工具或語料協助萃取特徵、以何工具分級等因素,進行研究與實驗,並建立一套新方法。首先進行前處理,再嘗試以單字、句型的數量或比例、句長、音節長、整合以上分析等各式特徵,支持向量機(Support Vector Machines)、隨機森林分類器(Random Forest Classifier)、決策樹分類器(Decision Tree Classifier)、卷積神經網路句分類器(Convolutional Neural Networks for Sentence Classification)等工具,進行將篇章分為高中一、二、三年級等三個難易度等級的測試,建立自動分級模型。最後製作成可供大眾使用的自動分級網頁。各項測試之中,最佳分類效能為整合各項特徵時得到的分類正確率65.04%,經模擬得知,此效能較過去研究,已有所提升。

Androcopter, using smartphones as flightcontrollers for Quadrocopters

This project proposes that smartphones are capable of steering a quadcopter, doubling as a flight controller unit. This means that sensor results from the smartphone’s IMU (inertial measurement unit) are compared with steering commands from the pilot received over Wi-Fi or a RC-transmitter. The idea behind this project was to build a cheap flight control for a quadcopter. Smartphones seemed to be the perfect device because of their dominance in the market. The first step was constructing the quadcopter’s frame. I first designed the frame on AutoCAD and then built a prototype out of aluminium. My search for a possibility to connect the engines or low level peripherals to a smartphone led to the «IOIO-Board». After collecting sufficient information about sensor fusion and control theory I started working on my own controller. Due to the frame’s large size the quadcopter is very stable and best suited for aerial photography. Engine control by smartphone using an «IOIO-Board» is fast enough for flight. A smartphone possesses everything needed to control a quadcopter. The disadvantage of using a smartphone is that the processor has to calculate multiple applications simultaneously. This makes it more difficult to guarantee the correct timing of operations. Nevertheless, external influences such as phone calls do not influence the flight behavior of the quadcopter. As work in progress I have experimented with the implementation of GPS and an onboard camera.

Bioinsecticide vs Aedes aegypti, vector of dengue, zika and chikungunya

The purpose of this research is to make an ecological insecticide that mixes the extracts of Piper tuberculatum, Annona muricata and Melia azedarach, that together in application cause mortality and repellence of the mosquito Aedes aegypti with the intention to help in the control of the diseases this mosquito is guilty of: dengue, zika and chikungunya, and decrease the risk of infection by a safe and organic way.

An Innovative Design of Enhanced-Performance Solar Panel Using Heat Pipe and Thermoelectric Generator

Solar energy is a main source of energy that is expected to play a vital role in fulfilling the future global demand of electricity. Design of advanced photovoltaic (PV) system with high electric conversion efficiency is the key for collecting solar energy. A major obstacle hindering useful PV utilization is the deterioration of solar cell efficiency with temperature. The present results of experimentation have shown that there occurs a reduction of approximately 33% in the solar panel efficiency as the operating temperature increases from 45 °C to 68 °C at 1000 W/m2. Therefore, an innovative design of enhanced-performance solar panel using micro flat heat pipe (HP) and thermoelectric generator (TEG) is proposed and experimentally investigated in the presented project. To operate HP and TEG at highest possible efficiency, the condensation section of HP is innovatively cooled by utilize the condensed water inside the evaporator of air conditioner (which is usually between 5-7 °C). Two different types of silicon panel are used in the study: monocrystalline solar panel and polycrystalline solar panel. The results showed that a reduction in average solar panel temperature up to 25% is obtained. In addition, produced power was increased by as much as 50% when solar panel was cooled by the heat pipe. Finally, the feasibility study and cost analysis of the proposed hybrid system are discussed in details and presented.

以蛋白質體學方法鑑定人類肝癌細胞經蕾莎瓦治療之預後的潛力生物標記 Identification of Potential Prognostic Biomarkers in Hepatocellular Carcinoma Cells Treated with Sorafenib

肝癌是死亡率極高的癌症。目前並無非侵入性方法判斷標靶藥物治療效果。蕾莎瓦(Sorafenib)是一種使用於肝癌晚期治療的標靶藥物,但有些病患在治療過程中會出現抗藥性,因此可預測蕾莎瓦治療效果的生物標記相當重要。 血液中的生物標記可及時追蹤疾病進展與預後之評估。本實驗利用質譜法鑑定分析在肝癌細胞(HuH7)中加入蕾莎瓦模擬治療後肝癌的分子機轉,並透過生物資訊軟體了解蛋白質在HuH7細胞中所扮演的角色。我們發現Galectin-3 和HMGB1可能參與腫瘤細胞的增生和遷移,以西方墨點法觀察其表現量,發現Galectin-3 和HMGB1在受到藥物處理後,表現量皆有下降的情形。 蕾莎瓦可抑制B-RAF激酶進而阻斷MAPK pathway。MAPK pathway又可分成ERKs、JNKs和p38/SAPKs三類。為確認Galectin-3之訊息傳遞路徑,將蕾莎瓦和ERK抑制劑處理細胞,發現Galectin-3的表現量隨著時間而下降,證實Galectin-3的表現會受到ERK路徑調控。 Galectin-3與 HMGB1是極具潛力的生物標記可應用於蕾莎瓦的治療,希望這些生物標記可以應用在臨床上。