全國中小學科展

四等獎

Prismalla: Mist water collector

The lack of drinking water in human settlements triggers a series of problems that are linked and affect the development of humanity: health problems, lack of water security for companies, lack of jobs, insecurity, among others. We observe this problem in the communities of the municipality of Las Vigas de Ramírez, Veracruz, where there is a great problem with the water supply, although there is a high presence of mist. Faced with this situation, we undertook the task of investigating a water harvesting method that is easy to implement, operate and maintain. We investigated and analyzed the methods of mist condensation through physical barriers, finding that the polyethylene shadow mesh was the means to achieve this, because it allows the passage of the wind, it is very light, easy to manipulate and above all that it presents the phenomenon of percolation that allows water droplets of various diameters to be accommodated therein. We designed a device that allows to present a mist catchment area through a prismatic structure enabled with meshes and condensed water receivers, portable, easy to use and maintenance and very economical with a performance of 20 liters per day. To achieve our project, factors such as air humidity, dew point, wind speed and direction, height, temperatures and available spaces must be considered.

如「膠」似「漆」-台灣淡水渦蟲黏液黏性及誘導抗菌分析 Mucus Viscosity and Induced Antibacterial Analysis of Taiwanese Freshwater Planarian.

渦蟲黏液仿生應用評估,首先評估渦蟲黏液仿生材料黏著劑可行性,結果發現搖晃刺激能提高渦蟲黏液運動黏度 (5.17 mm2/s) 及承受正向應力程度 (3.25 ± 0.74 kPa)。不同收集渦蟲黏液方法,利用蛋白質電泳並以過碘酸硝酸銀染色法分析,皆可發現245 kDa醣蛋白,推測為黏液中黏性蛋白,未來將以LC-MS分析渦蟲黏液中245 kDa醣蛋白種類並推測其功能。第二部分為渦蟲黏液誘導抗菌分析,實驗發現爬行組、搖晃組及受傷組渦蟲黏液不會產生抑菌環,進一步將渦蟲置於大量環境細菌D (Staphylococcus haemolyticus) 中,一天後渦蟲自體分泌具有抗菌能力的黏液。最後進行渦蟲黏液細菌分析,發現黏液細菌編號M030 (Stenotrophomonas maltophilia) 能對環境細菌H (Staphylococcus haemolyticus) 產生抗菌能力,未來將使用API ZYM分析黏液細菌分泌酵素,與渦蟲黏液分泌酵素比較已推測其與渦蟲交互關係。

摻鈀鹵氧化鉍奈米晶體光催化還原二氧化碳

本研究將以BiOCl、BiOBr以及Pd/BiOCl的晶體製備二氧化碳還原之光觸媒,用以還原二氧化碳,期許能製造出具有經濟價值的還原產物,以緩解全球暖化並利用可再生能源。此外,我們藉由探討此類晶體在二氧化碳還原中的差異,比較加入不同鹵族元素及是否摻入鈀金屬對於光催化還原二氧化碳效率及產物的影響。 合成晶體後,我們透過X射線衍射儀(XRD)、掃描式電子顯微鏡(SEM)、能量散射X射線譜(EDX)進行晶體的鑑定,也確定Pd/BiOCl的晶體結構是以BiOCl為主體,且Pd鑲嵌在其表面。我們也以X光光電子能譜儀(XPS)了解晶體的鍵結型態及推測不同晶體表面的OVs相對含量,並以紫外光/可見光光譜儀(UV-vis)檢測樣品的能隙,推測其光催化性能。 我們發現摻入鈀的BiOCl晶體結構為分散的片狀結構,是三種晶體中唯一的奈米晶體,且能隙為三者中最小(2.46eV)、表面OVs含量也增加;表面附著的Pd奈米金屬顆粒更可以協助主催化劑的電子-電洞對維持分離狀態,促進其光催化效率。 最後我們將合成的BiOCl、BiOBr以及Pd/BiOCl晶體應用於光催化還原二氧化碳,並以氣相層析熱導偵測器(GC-TCD)及氣相層析質譜儀(GC-MS)檢測產物種類及產率,發現還原出的氣體產物有H2、CO、CH4。而總還原產物及含碳還原產物的產率皆以Pd/BiOCl為最高。

癌症治療新利器-奈米氧化鐵藥物磁性複合微粒之應用

溫熱化學治療(Hyperthermic Intraperitoneal Chemotherapy, 簡稱HIPEC),為將化療藥物加熱後灌注到腹腔內殺死癌細胞,但溫熱化學治療只能在開刀時使用,治療次數有限。為達到多次的熱化療效果,本研究開發奈米氧化鐵藥物磁性複合微粒(Nano iron oxide magnetic drug complex particles, NIOMP),可利用開刀時包覆複合微粒於腹腔,術後用磁場加熱,加上微粒化療藥物釋放,達到多次溫熱化學治療。NIOMP以鐵氧化物奈米粒子為核心,海藻酸鈉為外殼體,利用電紡法將前其與氯化鈣交聯產生凝聚性微粒。數據顯示最佳製作條件為16 kv高電壓、距離4 cm、噴速5μm/s,可得直徑大小約為200~450 μm穩定性高微粒。藥物釋放實驗顯示,NIOMP於2~7小時藥物釋放速率較穩定。利用可變磁場之電磁效應加熱NIOMP中氧化鐵磁顆粒,可於30分鐘內快速升溫至43℃。細胞相容性測試結果得知,NIOMP對細胞無毒性。本研究改善HIPEC的治療限制,可多次針對腫瘤患部局部熱化學治療,未來將可改善病人存活率。

Development of UV-Protection Roofing Tile from Nitrogen-doped Graphene Quantum Dots (N-GQDs) for Rubber Drying Chambers

Improved methods of processing latex into rubber sheets will improve the incomes of small rubber producers. There are two ways in which latex can be processed into rubber sheets: fumigation and solar incubation. The fumigation method is expensive and produces pollution, but solar incubation can cause dark, sticky rubber sheets due to UV radiation, which reduces their value. A low-cost and environmentally-friendly solution to this problem was investigated here. A UV-protective roofing panel made using Nitrogen-doped Graphene Quantum Dots (NGQDs) was developed and tested. N-GQDs were made using the hydrothermal process for 2 and 4 hours (T2 and T4) and the solvothermal process for 4, 6, and 8 hours (TS4, TS6, and TS8). It was found that all types of N-GQDs absorbed light in the UV range, withT4 showing the greatest absorption. T4 had the greatest Fluorescent Intensity (FL) value, emitting blue light, while for the solvothermal method TS6 had the highest FL value, emitting red light. T4 and TS6 were chosen for further testing, and were applied to a clear roofing tile. After installing the roof on the chamber, the temperature inside was higher than outside. Then we measure the UV protection efficiency of the roof which was 93.27%. The average temperature was 45℃, which is the temperature for drying rubber sheets. Due to the roof’s capability to absorb UV radiation and heat the chamber, our N-GQDs roof has a great ability to produce higher-quality rubber sheets.

EVALUATION OF THE SURFACE TENSIO, LARVICIDAL AND ANTIBACTERIAL ACTIVITY OF PLANT EXTRACTS FROM THE LEAF OF THE ARACA TO COMBAT THE PROLIFERATION OF THE Aedes aegypti MOSQUITO IN STILL WATER CONTAINERS

The Aedes aegypti mosquito is one of the main transmitters of viral diseases in countries close to the equator. This vector promotes a series of generalized endemics that are difficult to control and prevent in these regions. Furthermore, the presence of bacteria in the environment favors the proliferation of mosquito larvae, which increases the probability of Aedes aegypti reproductive success. The Araçzeiro (Psidium guineense Sw.) is a plant present throughout the Brazilian Atlantic Forest and has in its composition, especially in the leaves, several substances that can be used to solve problems. Thus, we sought to verify the activity of flavonoids and polyphenols in terms of their antibacterial potential and the performance of saponins in their larvicidal potential, as well as surfactant, in order to prevent the accommodation of the mosquito in the water at the time of egg deposition and larvae respiration. The saponins were extracted from the araçazeiro leaf using a hydroalcoholic solvent and the flavonoids/polyphenols using methanol, the latter being subsequently rotaevaporated to maintain the non-toxic nature of the extract. Through the aqueous extracts, the content of total saponins by UV-VIS spectrophotometry, surfactant activity, larvicidal activity and toxicity were determined. In relation to the ethanolic extracts, the content of polyphenols and total flavonoids by UV-VIS spectrophotometry and high performance liquid chromatography (HPLC), antibacterial activity and toxicity were determined. The results showed that the aqueous extract has a satisfactory amount of saponins, as well as a surfactant potential due to the formation of foam and larvicidal activity in the two highest concentrations of the extracts. Ethanol extracts showed phenolic acids, especially gallic and ellagic acid, and flavonoids, especially catechin and quercetin, and antibacterial activity in most of the worked concentrations. Both extracts (aqueous and ethanolic) showed a dominant nontoxic character, which favors their use without risk to the environment, having an alternative and sustainable potential for controlling the proliferation of the Aedes aegypti mosquito.

彩色二維條碼手持產品開發之探討

QR Code是由黑白模組組成的二維數位條碼,掃描後可讀取儲存的訊息。受限於設計原理,QR Code使用二進位制儲存資料。增加模組數目可增加資料量,但若在條碼內塞進太多模組時,尺寸太小的模組將無法被掃描器讀取。此外,目前QR Code掃描器僅支援單張掃描,並無法應付同時多張條碼掃描的實務需求。 如能克服顏色辨識,理論上彩色二維條碼將能克服現行QR Code的限制,但市面上並無相關產品可供測試。因此本專題設計了一款10×10、具8顏色的"Colour Matrix",並利用Raspberry Pi開發Colour Matrix在手持裝置上運作的軟硬體來進行實驗。此實驗成功利用機器學習演算法在Raspberry Pi上進行的顏色辨識。開發的程式在單張掃描上效能與使用pyzbar辨識QR Code相當;在多張掃描方面,使用pyzbar辨識QR Code的解碼成功率為3.1%,而本專題的方法將成功率提升至92.4%,擴增數位條碼的使用範圍,具商用價值。

從天然物抓取微量抗癌藥物的工具之研究

本研究嘗試設計並合成出一具有特定結構之分子工具,期望利用化學反應的方式,以化合物結構的性質,與分子工具進行特定的反應,達到精準將目標具特定結構之少量化合物從巨量物質中分離的效果。 以苯環為基本結構,我們在反應中逐步加上我們所要的分子基團,以達成分子工具預期中的功能。在每一步的反應進行分離和純化之後,以NMR來觀察產物的結構與純度。以四步反應成功合成目標的分子工具後,我們以不同的方式測試其在葉片萃取液中大量化合物下的效果,證實分子工具能跟其中的特定成分產生反應,並被氟相溶劑分離出來,具有我們想要的部分功能。 在進行其他更進一步的測試之後,其可能可以成為一種新的方法,用於分離天然物中的一些目標化合物。

Automated Debugging System – Implementing Program Spectrum Analysis and Information Retrieval on Fault Localization

在程式專案開發中,偵測錯誤常為最耗時的環節,進而影響整個專案的開發時長。而現今雖有些許輔助開發者提升偵錯效能的工具,但這些工具也只能藉由提供編譯執行中的資訊讓開發者省去偵錯時的繁瑣步驟,仍須開發者自行評估每段程式碼的正確性。此研究透過程式段落分析與資訊檢索實現自動錯誤定位,在每個程式段落標記其成為臭蟲(bug)的可能性。在程式段落分析中,執行使用者之原始碼,並透過歸納最終結果為正確及錯誤之執行路徑差異分析出每個程式段落的可疑性。接著運用資訊檢索技術於資料庫中找尋相似之原始碼,並參考其偵錯結果優化現有之可疑性,形成最終之可疑性排名。此研究不只結合了上述兩種技術,更優化可疑程度之計算方法以及資訊檢索中的相似度比對機制,達到更完善的錯誤定位。(此指「臭蟲」非語法錯誤(Syntax Errors),而為邏輯錯誤(Logic Errors)。)

介電潤濕機制探討及應用-水電車

將液滴置於鋪上介電層的電極板,接上電壓時,液滴因表面張力及接觸角產生變化而移動,此現象被稱為介電潤濕,其裝置能讓生醫等產業進行精準的微量藥物配置。為了探討此現象原理及改善裝置,本研究測量液滴位於不同電壓之電極板上方時,液滴接觸角及介電層厚度;透過數值模擬計算系統總能量、視覺化系統的電位空間分布,並計算電容,以能量角度模擬液滴移動模式;對於平面式裝置在長時間移動水珠後,產生水珠移動速率趨緩,甚至朝反方向移動的現象給予解釋;改良文獻中平面式和雙層式的電潤濕裝置,將雙層式上板改為導線。因為形狀酷似電車,因此我們稱其為「水電車」,此裝置保留高電容特性的同時,降低阻力。實驗證實其水珠移動能力優於平面式裝置,除了使液滴更好移動外,相較於封閉的雙層式裝置,開放式系統的特點能讓生醫研究人員更方便置換樣品。