2021年

Tissue engineering has developed novel therapies such as many types of wound dressings, bio-pads, scaffolds and bandages, in order to reduce the effects of deep and extensive skin wounds. Here, we have produced an electrospun nanofiber scaffold, based on biodegradable materials such as gelatin (as a natural and hydrophilic polymer) and cellulose diacetate (with optimal biodegradability), in order to increase wound healing using nanotechnology. We also used green tea extract for its anti-oxidant and anti-bacterial effect, to improve the biological properties of the scaffold. In the fabrication process, two polymer solutions: 1. Gelatin (with acetic acid solvent) and 2. Cellulose Diacetate (with acetone solvent) mixed with green tea extract, were prepared. Then they were spun using a two-nozzle electrospinner to produce a hybrid nanofiber scaffold. SEM images showed enough finesse and uniformity of the produced scaffold to simulate the extracellular matrix. Further, measuring the contact angle of water droplet and the web surface, indicated optimal hydrophilicity of the nanofiber scaffold, which controls the level of scaffold degradability and cell adhesion. Also, the results of antibacterial tests for two bacterial strains (E. coli and S. aureus) showed the antibacterial characteristics of the extract-containing scaffold. In addition to previous tests, evaluation of fibroblast morphology on the nanofiber scaffolds, indicated appropriate cell adhesion and expansion, that confirms the biocompatibility of this produced scaffold.

It is known that copper foil undergoes a color change in heating by oxide thin layer formation. Therefore, we focused on the color change by the oxidation of brass foil. Brass foil (Akaguchi (Cu87%Zn13% alloy) and Aoguchi (Cu85%Zn15% alloy)) also undergoes color change by oxidation, and it shows heating time and temperature dependence. Brass foil need longer heating time to appear color change than copper foil, and we can visually confirm that the brass has corrosion resistant. In addition, color change of brass foil depends on the percentage of copper in the brass, and Aoguchi shows rapidly color change in same heating condition. We show that brass has different physical properties than copper, even with a high percentage of copper in brass, and this was verified through comparison using diffusion length and RGB data in Aoguchi and Akaguchi. We demonstrate these colored brass foils are used as art materials, and our results expanded material using possibility of brass foil.

In today's world, medicine is very advanced, thanks to which many diseases that were previously considered incurable, are now treated almost all over the world. But, unfortunately, some diseases are still incurable and can only facilitate their course. One such disease is Raynaud's disease or Raynaud's syndrome. Statistics show that worldwide the percentage of patients with this disease is 3-4%. Raynaud's disease is a paroxysmal spasm of the arteries of the fingers of the hand, rarely the feet when cooling the extremities. As mentioned earlier, this disease is incurable. That is why the creation of a device that can help people overcome many inconveniences due to the inability to stay in the cold without gloves or the problem of discomfort in heated gloves is relevant. And one of the solutions to this problem is to create special heated gloves. This work is also relevant, because even existing treatments, such as medication and conservative, do not completely solve the problem of reducing the sensitivity of the hands when cooled or even the slightest moisture on the palms. Also, these methods are very expensive, so our device will be cheaper and more affordable than existing ones. When using our gloves together with the two already mentioned methods, the treatment will be more effective. Unfortunately, medical and conservative treatments will lead to complications over time, so we not only maintain sensitivity in the hands, but also prevent further amputation of the upper extremities and the emergence of human health problems associated with the effects of drugs on the whole body. Nowadays, people work hard to be able to live well, but it is difficult for people with Raynaud's phenomenon to do so, as the sensitivity of the upper extremities decreases during the exacerbation of the disease. It is important for us to maintain the sensitivity of the hands by normalizing the thermal balance of the hands, which leads to the elimination of spasms of the atria of the hand. The aim of the work is to create a simple and effective means to normalize and maintain the thermal balance of the upper extremities, in order to reduce the loss of sensitivity of the hands in patients, as well as reduce the likelihood of spasms of the arteries of the fingers. The subject of the study is the course of Raynaud's disease and the current treatments for it. The aim of the study is the creation of special gloves that can stop spasms of arteries and maintain blood flow in them by balancing the heat balance in the hand, and depriving patients of the disease during their wearing During the work the following tasks were set: - to theoretically investigate the peculiarities of Raynaud's disease; - to analyze the existing clothes on the market with heating; - to develop and improve its own design of heated gloves, which will be affordable and easy to use. - calculate the cost of gloves taking into account all factors

Nine years ago, the Great East 日本 Earthquake caused the spread of a large amount of radioactive materials. Even now, the amount of contaminated water is increasing at a rate of 180 tons per day, and it is said that the storage tanks for the contaminated water will run out of space in the next two years (Fig. 1). If the contaminated water is discharged into the ocean, it will cause reputational damage to the fishing industry, and the environmental pollution. We are conducting to research to prevent it from happening. In the wake of the nuclear accident, the senior started water quality surveys at Chaya Marsh near the school. During the survey, they found (Chara braunii, Fig. 2), (Nitella axilliformis, Fig. 3), Closterium moniliferum (Fig. 4), and (Nostoc commune, Fig. 5).

The entry of nutrients into the environment can cause the creation of eutrophication of aquatic ecosystems. One of the methods of removing nutrients from effluents is the use of algae. Algal purification is a new and inexpensive technology for this purpose. The present study investigated the rate of cell growth and nutrient removal of urban wastewater in Bandar Abbas in winter 2020 by the Chlorella vulgaris microalgae in the phycolab of Fisheries Research. Treatments with different dilutions (0%, 25%, 50% and 75%) were prepared; in addition, specific growth rate, cell density and removal efficiency of phosphate, nitrate, nitrite were examined during a 14 day period with initial constant density (1×10⁶ cells / ml ) of microalgae. The results indicated that 0% and 75% dilution had the highest and lowest cell densities (8.675×10⁶ and 56.633×10⁶), respectively; moreover, they had the specific growth rate (0.166 and 0.311). Furthermore, there was a significant difference between them (P≥ 0.05). The highest nitrate and nitrite removal efficiencies were -40.75 and -79.84 in effluent dilution of 50%; in addition, the lowest were 1.26 and -40.26 in dilution of 75% and 25% respectively. Phosphate had the highest removal efficiency at 0% dilution with a mean of -79.65 that showed a significant difference with the lowest at 25% dilution (P≥ 0.05). Therefore, high or low levels of nutrients can affect the removal efficiency and growth rate of microalgae.

This underwater remote operating vehicle (ROV) is designed with and without tethered operation. The operator can control the ROV from the real time first-person view in graphical user interface combined with sonar and object detection function when the tether is attached to perform search and rescue. The control tether with fiber optic lighting cable establishes a guided link medium between the possible search victim location and the rescue team. When the tether is detached, rapid deployment by a predefined set of instruction to achieve further operation range. The intelligent technologies of signal processing were used for object recognition, collision detection and sonar scanning data to enhance underwater operation. Autonomous driving is based on software development with limited capability to run in unrestricted open areas. We have achieved the design intent and confirmed the performance data in the laboratory boundary conditions.

本研究試圖找出一些策略，以了解在mxn的格狀街道中，最少應該放入幾個吸螞蟻的裝置，便保證能抓到所有螞蟻。這問題等價於在圖G(m,n)中，最少應放入幾個紅點後，便能使G中的所有環都能碰到至少一個紅點。更等價於在圖G(m,n)中，最少應扣除幾個點後，便可形成一森林。 我們將這些點數記作k(m,n)。特別地，當m=n時記作k(n) 。本文推得：k(m,n)≧[mn+1/3]，並將等號成立時的k(m,n) 稱為完美的。經過構造後發現k(2n)、k(3,n)、 k(3n,m)、k(2+6m,2+6n),k(4+6m,4+6n) , 亦為完美的，並且將k(m,n)壓到只剩兩種可能。也得知了在無限擴張的格子圖中被移除點的密度為1/3。

近年來，再生醫療利用幹細胞幫助組織器官新生的方法已有長足進步，但仍然面臨許多的瓶頸。例如: 幹細胞注射進入人體以後，無法繼續分化生長成所需組織。最近，高能磁場的使用也是醫學界蓬勃發展的議題，我們試圖利用高能磁場誘導幹細胞的分化，希望可以增加幹細胞分化的效能，這是一創新的嘗試。我們比較新型高能磁場(RMS)與對照組於骨髓幹細胞(BMSCs)的分化效果，發現RMS 中叢集式刺激(iTBS)的SOX9和COL10的基因表現與免疫組織化學染色明顯優於15Hz RMS 與對照組。最佳的刺激設計為強度50%的iTBS連續施打五天。我們亦發現每回合900 pulses有優於每回合600 pulses的趨勢。此實驗證實iTBS能夠增加BMSCs在體外的軟骨分化表現，反映在基因表現層次到膠原蛋白合成的層次。未來，此方法將進一步使用於動物實驗，期望擴展到臨床上用於退化性關節炎的治療，對再生醫療發展有所幫助。

This study considered the tensile and flexural characterization of new lighter and cheaper hybrid composite materials to replace the existing insert panel for the currently available bulletproof vest. The materials chosen included a natural fibre, i.e., kenaf fibre, chemically treated with sodium hydroxide solution, and, as a means of recycling, used x-ray films with a surface treatment. Using the traditional hand lay-up method, the materials were fabricated into seven layers of different configurations, which were then subjected to tensile and flexural tests. The findings showed that one of the configurations that consisted of both treated materials had a tensile strength of 396.9M Pa, which is quite strong, and a flexural modulus of 6.24G Pa, which makes it flexible enough to be made into wearable equipment. This configuration was then chosen to be the base design for the specimen subjected to impact test. The interfacial bond between the two distinct materials proved to be a major issue, even with the help of fibre treatment. Therefore, some improvements need to be made for the material to be comparable to existing materials performance-wise hence making this configuration suitable for ballistic application.

Revealing fascinating and educating concepts in a field of astronomy usually requires expensive equipment. Therefore, most schools have very little practical equipment to teach astronomy. I wanted to investigate the Sun’s track using a simple apparatus that can be afforded by many schools instead of using an expensive one.