浮萍在逆境下葉狀體會有分離的現象，本研究證實：浮萍透過葉狀體分離，增加逃離逆境的機率，提升族群生存率。此分離機制受到過氧化物質(H2O2)的調控，逆境下，浮萍母葉節處(node)的H2O2含量上升並誘導細胞死亡，進而造成連接構造斷裂，另能透過乙烯途徑活化纖維素分解酶使葉狀體分離。我們也發現青萍及紫萍具不同生存策略：青萍對H2O2的高敏感度使其能在逆境下快速分離，進而降低其葉狀體間的內聚力，更容易藉由風吹或水流加速逃離逆境；紫萍則對H2O2較不敏感且內聚力大，以較大的單一個體及對逆境的高耐受性來渡過危機。蛋白質含量極高的浮萍是蛋白質補給品的好原料，期待分離機制的深入研究能應用在浮萍種植上，使其快速分離提升產量，應對將到來的糧食危機。

圓周上相異n個點，將圓周分割成n段弧，每次每個點沿逆時針方向變換成與下一點所成弧之中點，若某點經m次變換後回到初始點，則m的最小值以及m的所有可能值為何？我們發現，m的最小值為n+2。更進一步發現，m的充要條件為m≧n+2且m≠kn-1, kn, kn+1，其中k為正奇數。接著，我們將問題一般化，圓周上相異n個點，沿逆時針方向變換成與下一點所成弧之p:q處，若某點經m次變換後回到初始點，則m的最小值以及m的所有可能值為何？我們發現，若p, q∈N，(p,q)=1，當變換次數r足夠大時，此n個點的位置會收斂至圓周上n等分點，同時，此n個點會在變換T=n(p+q)/(n,p)次後再次收斂至相同的位置。在這篇研究中，我們推導出任意點Pi變換r次後的點之位置坐標Ai(r)的一般式，不失一般性，我們針對P0求出A0(r)的最小極端值Lr與最大極端值Ur，在變換次數r足夠大時，透過觀察Lr與Ur對應到圓周上的收斂位置所形成的區間是否涵蓋原點，可預期P0變換r次後可否回歸。此外，我們也針對n個點具特殊初始位置座標來研究其回歸性質。

尿酸氧化酶參與嘌呤代謝，然人類尿酸氧化酶基因已退化，易使過量尿酸沉積於關節造成痛風，近年來微生物源尿酸氧化酶之酵素工程改良，逐漸被應用於尿酸檢測與降解藥物，因此具極高研發價值。 本研究針對微生物源尿酸氧化酶進行基因體探勘，篩選出抗輻射奇異球菌(Deinococcus radiodurans)及耐熱雙球桿菌(Thermobispora bispora)源尿酸氧化酶基因，以蛋白質異源表現與金屬螯合層析法純化取得重組尿酸氧化酶，進行酵素動力學、熱穩定分析、結構解析、金屬離子耐受性分析與尿酸檢測應用。在最佳反應條件下，抗輻射奇異球菌源酵素於30 ℃之Km與Kcat為679.03 μM, 30.33 s-1；耐熱雙球桿菌源酵素於70 ℃之Km與Kcat為191.31 μM, 12.85 s-1。此外，我們已解析耐熱雙球桿菌源尿酸氧化酶結構，發現其羧基端之特異性構型可能與熱穩定性有關。本研究以此兩種尿酸氧化酶為酵素工程改良標的，盼未來能研發作為快速篩檢與臨床治療之生物替代藥物。

澎湖牡蠣養殖受扁形動物危害嚴重但缺乏相關研究。本研究首次採集活體澎湖蚵蛭Stylochus ( Imogine ) orientalis splendida Bock, 1913進行捕食行為研究。觀察澎湖蚵蛭捕食過程分為攻擊期、捕食期和消化期，並首次報導攻擊期中發現新型的離體咽。離體咽具負趨光性( P <0.01 ** )能朝向牡蠣殼內暗處移動，使其開閉殼頻率與死亡率增加。離體咽也顯著影響文蛤死亡率 ( P <0.01** )，20條以上離體咽即可導致文蛤死亡率 60% 以上，造成文蛤外套膜萎縮，且與數量呈高度正相關 ( R2 = 0.964 )，外套膜切片顯示離體咽可導致外套膜肌肉變細且形成許多空洞。經離體咽均質和硫酸銨沉澱法萃取蛋白質後，通過SDS蛋白質電泳比較澎湖蚵蛭離體咽、咽、與其他部位的粗萃物，分離出目標蛋白質，以MALDI-TOF質譜儀分析分子量約為10 kDa。證據顯示離體咽是蚵蛭成功捕食牡蠣的重要關鍵，亦是海洋扁蟲從未被報導過的新行為。

The entry of nutrients into the environment can cause the creation of eutrophication of aquatic ecosystems. One of the methods of removing nutrients from effluents is the use of algae. Algal purification is a new and inexpensive technology for this purpose. The present study investigated the rate of cell growth and nutrient removal of urban wastewater in Bandar Abbas in winter 2020 by the Chlorella vulgaris microalgae in the phycolab of Fisheries Research. Treatments with different dilutions (0%, 25%, 50% and 75%) were prepared; in addition, specific growth rate, cell density and removal efficiency of phosphate, nitrate, nitrite were examined during a 14 day period with initial constant density (1×10⁶ cells / ml ) of microalgae. The results indicated that 0% and 75% dilution had the highest and lowest cell densities (8.675×10⁶ and 56.633×10⁶), respectively; moreover, they had the specific growth rate (0.166 and 0.311). Furthermore, there was a significant difference between them (P≥ 0.05). The highest nitrate and nitrite removal efficiencies were -40.75 and -79.84 in effluent dilution of 50%; in addition, the lowest were 1.26 and -40.26 in dilution of 75% and 25% respectively. Phosphate had the highest removal efficiency at 0% dilution with a mean of -79.65 that showed a significant difference with the lowest at 25% dilution (P≥ 0.05). Therefore, high or low levels of nutrients can affect the removal efficiency and growth rate of microalgae.

我們的視覺能力是大腦將感官所觀察到的物體進行辨認，由於物體受到形狀、線條和顏色的變化，加上人們的生理、心理原因，而產生與實際不符合的視錯覺。為探討眼睛對不同顏色赫曼方格的視錯覺，我們以標準化的情境和RGB 色環中的對比色、相近色和互換色定義電腦上赫曼方格顏色，進行實驗。研究發現黑白配色所看到鬼影人數最多，而綠紅配色卻較少人看到鬼影。因此我們用側抑制現象與感光細胞進行討論、分析，得出傳統黑白赫曼方格，受到側抑制作用的影響最為明顯，而其餘顏色變因的赫曼方格，對於紅藍綠視錐細胞和桿狀細胞會有不同程度的刺激，產生更複雜生理錯覺。此外我們延伸去探討不同顏色的格子襯衫對於受試者消費行為的影響，研究發現生理視錯覺會影響受試者的消費行為，錯覺較少比較多人願意購買；除此之外社會觀感與年齡層皆會影響受試者的消費行為。

Heavy metals contaminate many bodies of water, posing a health risk to not only organisms that live and use the water in these areas, but also to the humans that live nearby. Chlorella vulgaris, a microalga, is one organism whose chlorophyll a fluorescence can indicate the presence of these substances, detecting any changes in concentrations using fluorescence microscopy and other fluorescence devices. The study explores the sensitivity of C. vulgaris to the heavy metal zinc where the algae was exposed to five concentrations of zinc: 0 ppm, 5 ppm, 10 ppm, 50 ppm, and 100 ppm. The fluorescence of the samples was observed with a fluorescence microscope on days 0, 4, 7, and 12, where the algal samples were adapted to the dark for 5 minutes, then exposed to light for 90 seconds. The values of the minimal and maximal fluorescence of the samples in the dark were noted. There is a significant difference in the values of the minimal fluorescence, maximal fluorescence, and maximum quantum yield, a value derived from the minimal and maximal fluorescence, at the highest concentration, 100 ppm, from the other treatments for the entirety of the experiment. The significantly low values at 100 ppm and the calculated EC50 of 75.70 ppm indicate that C. vulgaris is indeed a viable indicator for zinc detection at this and higher concentrations of zinc.

Unaffordable healthcare and excessive plastic waste are both alarming issues that are plaguing modern society. Recent studies conducted by the World Health Organisation (WHO) report that about 15% of the world's population suffer from a form of disability, of which 50% of the demographic cannot afford adequate health care. Furthermore, 8 million metric tons of plastic annually enter our oceans (apart from the 150 metric tons that currently circulate our oceans!). In conjunction to the global plastic pollution crisis, unnecessary invasive surgery is currently being done on amputees. Many of these desperate patients are forced to pay exorbitant prices in order to live a normal life with bionic prosthetics. The solution… Project Limbs - an EEG, 3D printed prosthetic printed from recycled plastic. Signal processors will be implemented to build an affordable and easy-to-use ‘mind controlled prosthetic hand’, that requires no invasive surgery.

自古以來，致病細菌便是人類免疫系統的強敵，加上近年來抗生素的濫用使細菌在具有抗藥性後更加棘手，相對的人體免疫系統愈顯衰弱。本研究成功合成了一個可以連結細菌和免疫細胞的複合分子，此複合分子是由萬古黴素、連接單元和生物素組成，稱之為複合分子VLB（Vancomycin-Linker-Biotin）。其中萬古黴素用來辨識並結合細菌細胞壁上的肽聚醣，生物素則可以與抗體結合並徵召免疫細胞。 我們以螢光基團及抗體等，實際測試複合分子VLB對細菌的辨識力，確認其能在萬古黴素端與革蘭氏陽性菌連結，並在生物素端與抗體結合。我們藉由複合分子VLB增加細菌及免疫系統之間的親和力，以提升免疫細胞辨識細菌的能力，使其更快更有效地對抗細菌，解決多重抗藥性細菌難以擊敗的問題。利用本研究合成抗體徵召分子的方法，大幅提升免疫細胞對致病細菌的辨識力，將來可望有效地應用在臨床醫學上。

Chromene(色烯或苯並吡喃)或chromane(色原烷或2.3-二氫苯并哌喃)及pyrrolidine(吡咯烷)的衍生物是許多藥物和具有生理活性天然物的重要結構單元。含有chromene或chromane的化合物在消炎、抗真菌的研究中表現出良好的活性，而pyrrolidine出現於尼古丁等化合物中。本研究利用亞胺葉立德前驅物與米氏酸衍生物在鹼性催化劑的作用下，篩選出溶劑、催化劑、當量數，找出合成Chromeno [4,3-b] pyrrolidine產率最高的條件。利用此優化條件，改變不同的受質，在苯環上改變不同取代基，探討其反應性，增加其未來應用的多樣性，嘗試利用掌性催化劑，合成出具有光學活性的產物，並建立資料庫。