全國中小學科展

二等獎

藥物骨架Chromeno [4, 3-b] pyrrolidine的合成方法之探討

Chromene(色烯或苯並吡喃)或chromane(色原烷或2.3-二氫苯并哌喃)及pyrrolidine(吡咯烷)的衍生物是許多藥物和具有生理活性天然物的重要結構單元。含有chromene或chromane的化合物在消炎、抗真菌的研究中表現出良好的活性,而pyrrolidine出現於尼古丁等化合物中。本研究利用亞胺葉立德前驅物與米氏酸衍生物在鹼性催化劑的作用下,篩選出溶劑、催化劑、當量數,找出合成Chromeno [4,3-b] pyrrolidine產率最高的條件。利用此優化條件,改變不同的受質,在苯環上改變不同取代基,探討其反應性,增加其未來應用的多樣性,嘗試利用掌性催化劑,合成出具有光學活性的產物,並建立資料庫。

Using EEG Neuro-Feedback technology to control a prosthetic hand

Unaffordable healthcare and excessive plastic waste are both alarming issues that are plaguing modern society. Recent studies conducted by the World Health Organisation (WHO) report that about 15% of the world's population suffer from a form of disability, of which 50% of the demographic cannot afford adequate health care. Furthermore, 8 million metric tons of plastic annually enter our oceans (apart from the 150 metric tons that currently circulate our oceans!). In conjunction to the global plastic pollution crisis, unnecessary invasive surgery is currently being done on amputees. Many of these desperate patients are forced to pay exorbitant prices in order to live a normal life with bionic prosthetics. The solution… Project Limbs - an EEG, 3D printed prosthetic printed from recycled plastic. Signal processors will be implemented to build an affordable and easy-to-use ‘mind controlled prosthetic hand’, that requires no invasive surgery.

Removal of Nutrients by Chlorella Vulgaris Microalgae in Bandar Abbas Municipal Wastewater

The entry of nutrients into the environment can cause the creation of eutrophication of aquatic ecosystems. One of the methods of removing nutrients from effluents is the use of algae. Algal purification is a new and inexpensive technology for this purpose. The present study investigated the rate of cell growth and nutrient removal of urban wastewater in Bandar Abbas in winter 2020 by the Chlorella vulgaris microalgae in the phycolab of Fisheries Research. Treatments with different dilutions (0%, 25%, 50% and 75%) were prepared; in addition, specific growth rate, cell density and removal efficiency of phosphate, nitrate, nitrite were examined during a 14 day period with initial constant density (1×10⁶ cells / ml ) of microalgae. The results indicated that 0% and 75% dilution had the highest and lowest cell densities (8.675×10⁶ and 56.633×10⁶), respectively; moreover, they had the specific growth rate (0.166 and 0.311). Furthermore, there was a significant difference between them (P≥ 0.05). The highest nitrate and nitrite removal efficiencies were -40.75 and -79.84 in effluent dilution of 50%; in addition, the lowest were 1.26 and -40.26 in dilution of 75% and 25% respectively. Phosphate had the highest removal efficiency at 0% dilution with a mean of -79.65 that showed a significant difference with the lowest at 25% dilution (P≥ 0.05). Therefore, high or low levels of nutrients can affect the removal efficiency and growth rate of microalgae.

Process of making a new environmental friendly straw

本研究首先製作「蔬菜紙吸管」,其耐水性及吸飲功能不佳,改以海藻膠製作吸管,經歷多次改良後的「第三代海藻膠吸管」其質地近似塑膠吸管,但吸飲功能仍然不佳。接著,以海藻膠為膠著劑;紅茶粉為骨材,成功製作出耐水性、吸飲功能較佳且可散發紅茶香氣的「紅茶吸管」。提高添加紅茶粉之比例,能有效提升吸管硬度,可應用在飲料封口膜之戳入,在冰水、熱水中均可長時間維持吸飲功能,製作大口徑「紅茶吸管」,可輕易吸飲波霸珍珠,徹底解決吸飲波霸珍珠之難題。自製擠出成型機械,可控制出料速度維持穩定,在滑軌上以直線移動,可製作出粗細一致且筆直的吸管,最後試製綠茶、咖啡、檸檬等調味吸管,均會飄出天然原料之香氣,頗具商品化之潛力。

Chlorella vulgaris chlorophyll a fluorescence as a potential indicator for zinc and nickel detection

Heavy metals contaminate many bodies of water, posing a health risk to not only organisms that live and use the water in these areas, but also to the humans that live nearby. Chlorella vulgaris, a microalga, is one organism whose chlorophyll a fluorescence can indicate the presence of these substances, detecting any changes in concentrations using fluorescence microscopy and other fluorescence devices. The study explores the sensitivity of C. vulgaris to the heavy metal zinc where the algae was exposed to five concentrations of zinc: 0 ppm, 5 ppm, 10 ppm, 50 ppm, and 100 ppm. The fluorescence of the samples was observed with a fluorescence microscope on days 0, 4, 7, and 12, where the algal samples were adapted to the dark for 5 minutes, then exposed to light for 90 seconds. The values of the minimal and maximal fluorescence of the samples in the dark were noted. There is a significant difference in the values of the minimal fluorescence, maximal fluorescence, and maximum quantum yield, a value derived from the minimal and maximal fluorescence, at the highest concentration, 100 ppm, from the other treatments for the entirety of the experiment. The significantly low values at 100 ppm and the calculated EC50 of 75.70 ppm indicate that C. vulgaris is indeed a viable indicator for zinc detection at this and higher concentrations of zinc.

以菸草探討電擊對植物免疫的影響

農作物常遭受病毒攻擊,造成重大經濟損失,但傳統的化學藥劑無法有效抑制病毒,且易殘留汙染環境。本研究旨在利用物理性的電擊模擬外界刺激,進而探討電擊對植物啟動水楊酸主導免疫反應的影響。實驗中以10伏特的電壓電擊菸草10分鐘,能使圓葉菸草(Nicotiana benthamiana)的水楊酸標誌基因PATHOGENESIS-RELATED PROTEIN 1(PR1)表現量提升,並使菸草鑲嵌病毒 (tobacco mosaic virus ; TMV)的感染斑點數下降。顯示電擊處理可以誘導水楊酸所主導的免疫反應,並增強整體抗病毒性。另外,相較於未電擊過的菸草,電擊後的菸草系統葉在接種TMV-GFP後PR1基因表現量提升,表示電擊可能對菸草系統性水楊酸相關抗性表現產生預起效應(priming),可以幫助植物對抗未來的病毒感染。

超立方體最小控制集建構方式的探討

本研究將至多8維的超立方體(hypercube)Qn最小控制集(minimum dominating set)MDS(Qn)建構方式一般化,並藉由同構(isomorphic)的分類討論提出的建構模式之唯一性與否。由文獻得出的各超立方體最小控制集大小γ(Qn)以及已知的控制集形式,並從控制集重複控制的次數R(MDS(Qn )),我們得出Qn的平方圖中最小控制集形成的子圖Qn2 [MDS(Qn )]可能的連通分量(component)數,最後透過Qn層狀圖(layered graph)中各層控制點數的運算,篩選得出可行的建構方式。 研究得出MDS(Q1 )、MDS(Q2)、MDS(Q3)、MDS(Q5)、MDS(Q7)只有一種同構;MDS(Q4)、MDS(Q6)有兩種同構,同時我們發現MDS(Q5)與MDS(Q6)構造上的關聯;Q8的情況較為複雜,我們先是證明了γ(Q8 )=32,並討論MDS(Q8)與MDS(Q7)構造上的關聯,提出了建構MDS(Q8)之方式。

陶瓷燒成新技術- 以家用微波爐及自製集熱盒燒製高溫陶瓷之研究Research on firing high temperature ceramics with household microware oven and self-made heat collection box

本研究以家用微波爐及自製集熱盒燒製高溫陶瓷,用於家用微波爐的集熱盒材料的材質以玻璃纖維為主體為佳,集熱材料使用碳化矽顆粒級配重量比為1:3(320目碳化矽:180目碳化矽) 有最佳的微波吸熱效率並半浸泡的方式沾黏3.02mm (10層)最好;集熱盒玻璃纖維與集熱材料碳化矽之間的高溫黏著劑,以體積比3:7(矽酸鈉:水)為最佳配比。以家用微波爐搭配自製集熱盒可於26.5分鐘便可燒結陶瓷上釉作品,與傳統電窯需480分鐘比較可大幅減少94.48%的燒製時間,且其耗費的能源可省去89.44%的電費,以家用微波爐及自製集熱盒燒製之陶瓷品與傳統電窯燒製之陶瓷品在洛式硬度儀上測試結果無明顯差異,是未來極具發展性的陶瓷燒成技術。

Crossing Number of Join Product of Some Graphs

A drawing of a graph G is a representation of G on a plane, with its vertices represented by distinct points, and its edges by arcs connecting the corresponding points. The crossing number of G is the minimum number of intersections between arcs across all possible drawings of G.

實驗室裡的飛行荷蘭人--複雜蜃景之探究 (Fata Morgana: the explanation of the 'Flying Dutchman')

複雜蜃景(Fata Morgana)專指擁有多重影像的特殊上蜃景,形成於高緯度海面上,也是「飛行荷蘭人」的主要成因。本研究主要藉由探討介質折射率梯度變化與觀察者高度位置等變因,釐清複雜蜃景形成與觀察的最佳條件。藉由控制高濃度糖水溶液擴散形成的密度梯度,我們在六十公分的水缸中重建出形成複雜蜃景的環境,主要是因為糖水溶液中的折射率梯度遠大於海面上空氣的逆溫梯度所造成之折射率變化。為了進一步解析光在複雜折射率介質中之行進模式,我們以綠雷射光入射糖溶液,在側向以相機紀錄光的行進軌跡,分析探討其折射現象。我們同時利用相機觀察放置於水缸另一側的模型船,藉以觀察實際蜃景的形成與演化。本研究中我們另發展一套光軌跡的模擬程式,以協助實驗的進行與驗證實驗的成果。藉由實驗與理論模擬相互映證,充分探討複雜蜃景的成像與形成的最佳條件。