三等獎

The billiard table is a cuboid with integer side lengths. A point-wise ball moves with constant speed along segments making a 45◦ angle with the sides and bounces on these. We allow the ball to start from any of the 8 corners, resulting in a periodic trajectory known as a corner path. The geometry of the path depends on the artihmetic properties of the side lengths (for example if these are pairwise coprime). Points of contact between the ball and edges, known as edge points, are inves- tigated and their characteristics like distribution explicitly described. This generalizes a previous work by Perucca, Reguengo da Sousa and Tronto of University of Luxembourg.

The human gut microbiome is integral to digestion, overall health, and metabolic disorder imbalances. Recent advancements in fecal microbiota transplantation (FMT) have highlighted the therapeutic promise of restoring healthy gut microbiota in populations with high incidences of diseases. Focusing on fecal DNA samples from healthy Asian individuals, this study examines the potential of novel Akkermansia strains, specifically Akkermansia muciniphila (Z62) and Akkermansia massiliensis (IR119), as next-generation probiotics for mitigating metabolic syndrome. A key aspect of the study is the investigation of short-chain fatty acids (SCFAs), which are produced and play a crucial role in regulating metabolic processes. SCFAs such as butyrate, acetate, and propionate are essential for energy provision to colon cells and exerting anti-inflammatory effects. The methodology involves selecting two Akkermansia strains, analyzing them through 16S rRNA and WGS, evaluating their growth and survival rates under acidic and bile-salt conditions, alongside their cell adhesion capabilities. The study focuses on the production of key short-chain fatty acids (SCFAs) and tryptophan derivatives by bacteria in regulating metabolic processes, as well as their anti-inflammatory effects on colon cells. Through in vitro assays, both strains exhibited survival in acidic/bile-rich conditions, though Z62 demonstrated superior adhesion to Caco-2 cells, suggesting a higher colonization potential. Metabolomic analysis revealed both strains produce SCFAs, including propionic and acetic acids, and indole metabolites, such as indole-3-propionic acid and indole-3-acetic acid, which are known to influence lipid metabolism and insulin sensitivity. In adipocyte cell models, IR119 significantly reduced lipid accumulation, while Z62 increased lipid presence. Furthermore, IR119 reduced pro-inflammatory cytokine levels, including IL-6 and TNF-α, suggesting potential for inflammation mitigation. The future potential of IR119 as a therapeutic probiotic is extraordinary in addressing complex metabolic and inflammatory diseases, which open new avenues for managing chronic inflammatory conditions like type 2 diabetes and cardiovascular disease. Future clinical trials could refine IR119’s efficacy, positioning it as a leading probiotic in preventive and therapeutic contexts.

In radiation treatments and manned interplanetary space travel, radiation is one of the biggest problems. The radiotolerance of cancer cells makes it necessary to apply high doses to surrounding healthy tissues by subjecting the cells to heavy stress. With regard to space travel (which involves a minimum travel time of 6 months) (1,2) the danger concerns cosmic radiation which is capable of inducing genetic mutations that, in turn, can evolve into very serious pathologies, such as cancer, damage to dendrites consequently compromising synapses. The project is aimed at developing a technology that can address these issues and aims to make human DNA radioresistant. This study involves a nucleosome-binding protein called DSUP (Damage Suppressor Protein) unique to the tardigrade Ramazzottius Varieornatus and the subject of its radioresistance. It can theoretically safeguard genetic material damaged by radiation. *Internship theme at the Pino Torinese Astronomical Observatory and the DISIT-UPO Environmental Molecular Toxicology Laboratory. The study molecule: Numerous tests have been carried out through the "in silico" approach geared toward mathematical modeling of its protein structure and complex mechanisms of action simulated through artificial intelligence systems, followed by direct laboratory analysis involving biosynthesis of DSUP by genetically modified bacteria and related tests. Both approaches, applied synergistically, aim to make it accessible and useful for the protection of human health.

本研究探討隨機生成數列的長度期望值。一個籤筒中有n支籤，編號分別為1,2,3,…,n，每抽出一支籤，就將抽取的編號寫在紙上，形成一個數列。數列只能向左右兩端添加項，不能從中插入。抽出的籤若大於目前數列的最大項，則將抽出的數寫在目前數列右邊；抽出的籤若小於目前數列的最小項，則將抽出的數寫在目前數列左邊；抽出的籤若介於目前數列的最小與最大項之間，則操作結束。基於此想法，研究者將數列依照添加項的方向分為「單向數列」與「雙向數列」兩類。顧名思義，單向數列只能向一端延伸（本研究不失一般性討論往右延伸），雙向數列代表可以向左右兩端延伸。此外，研究者又將數列分為「嚴格遞增減」和「非嚴格遞增減」兩類。在生成原理上，嚴格遞增減等價於「抽後不放回」；非嚴格遞增減等價於「抽後放回」。在這樣的規則下，本研究探討了n支籤抽完放回與不放回時，單雙向隨機生成數列的長度期望值之通解，並成功證明了一些恆等式及性質。

Wind energy is one of the most promising and rapidly growing sources of renewable energy, although maximizing its efficiency while minimizing noise remains a challenge and limits its widespread adoption. The emergence of toroidal propellers, which have gained popularity for producing comparable thrust levels to traditional drone propellers while producing less noise, could mitigate this. This study aimed to develop a small-scale toroidal HAWT and compare its power and noise output to a conventional rotor design under similar wind velocity conditions. 15-centimeter diameter models of the toroidal and conventional rotors were created in Fusion 360 and simulated using Ansys Fluent to identify the significant aerodynamic characteristics that positively affect the blades’ power coefficient. The toroidal design with the greatest simulated power output at low tip speed ratios (TSRs) was then 3D printed and physically tested in a wind tunnel against the control rotor. The experimental results confirmed that the toroidal design had greater power coefficients at lower TSRs compared to the control rotor. The toroidal rotor started operating at a wind velocity of 3 m/s compared to the control rotor’s 6 m/s, which indicates superior start-up characteristics. While the toroidal rotor produced half the power output of the control at the highest tested wind speed of 7 m/s, it emitted 18 decibels less noise and showed a reduction in discernible noise between frequencies of two to five kilohertz. The results from this study show its potential in low-noise wind turbines within low-wind velocity environments.

Conspiracy theories are generally perceived as irrational, absurd and as having a negative effect on our reputation. Yet some people do not see them as such. This may lead us to wonder why and how an individual would come to believe or support such statements. In this work, the primary goal is to obtain the level of absurdity of various conspiracy theories so that they can be used in experiments designed to test Williams' “Strategic Absurdity Hypothesis”. In addition, this study attempts to demonstrate the link between conspiracy mentality and feelings of ostracism. In this research, I analyzed a group of 47 participants recruited via social networks in May 2023. The survey collected their demographic information, their conspiracy mentality, their feeling of ostracism, their knowledge of conspiracy theories and their perception of absurdity toward them. The results were analyzed using correlations and linear regressions. The results show a negative correlation between conspiracy mentality and the perception of absurdity for most theories. In other words, the higher a participant's conspiracy mentality, the less absurd the theory is perceived to be. Therefore, hypothesis (I) is partially supported. On the other hand, hypothesis (II), which says that ostracism predicts conspiracy mentality, is not supported by the results. These results are in line with Williams' “Strategic Absurdity Hypothesis” and Sterelny's signaling theory, explaining that an individual, by expressing agreement with a conspiracy theory typically perceived as absurd, damages their reputation in the eyes of others to show that they belong to the group. However, for the theories relating to COVID-19 and climate change, the conspiracy mentality does not predict the vision of absurdity, suggesting that their currentness and media coverage influence whether they are used as signals. The literature does not fully agree with our results and still presents very divergent opinions regarding the links between feelings of ostracism and conspiracy mentality. Indeed, it remains difficult to determine whether conspiracy mentality influences ostracism or vice versa. In conclusion, this study provides new ideas for future research on the origins and impact of the conspiracy theories.

Recently,thefeedpricesforlivestockfarmshavebeencontinuouslyincreasing, while the prices of calves have been declining, leading to many livestock and dairy farms facing financial losses. If livestock farms are affected by diseases such as foot-and-mouth disease, they suffer significant losses. This is because reducedproductivityinlivestocknotonlyaffectstheirproductionbutalsoentails substantial costs for vaccines and treatments. Therefore, there is a need to explore how to effectively prevent diseases, focusing on common diseases in cattle such as subclinical mastitis and mastitis, and alleviate the burden on farms economically and environmentally. This study aims to investigate the production of bacterial growth-inhibiting straw bedding using substances such as illite and charcoal to contribute to disease prevention.

When doing an experiment to produce colloidal ferric hydroxide, the bottom of the beaker used was colored in yellow-brown with thin film interference. This phenomenon is well-known, but the cause has not been clearly studied. As a result of the research, the coloration on the bottom of the beaker is caused by β-FeOOH forming a thin film which is chemically bonded with Si-OH on the glass surface. Also, the amount of β-FeOOH depends on the number of experiments, the area of the bottom of the beaker, and the concentration of FeCl3 aq. We found that it can be possible to determine the amount of β-FeOOH from the formula m=knsc and the adhesion constant was found to be 6.8✕10-3 (L/m2). In addition, from machine learning we predicted that the thin film thickness becomes thicker as it moves away from the center.

As of 2021, there are 368 harmful algae blooms and over 6000 invasive species in the United States of America. Furthermore, it is reported that the United States spends more than 11.1 billion dollars per year on clean-up methods for marine debris. However, there currently isn’t a method to monitor aquatic problems simultaneously, autonomously, and efficiently, creating a capability in the aquatic biosecurity sector. To combat this, we have created an autonomous vehicle that can conduct long-term monitoring of freshwater bodies for up to 60 hours.

Theseparation, purification, and recovery of precious organic solvents is a huge challenge for many industriesincludingpetroleumandpharmaceuticalcompanies,sincethesecompaniesusehugequantities of organic solvents [1-2]. Natural dissolvable nanofiltration(ON)has atremendous potential for supplantingafewenergy-concentratedcrudepurgingtechniques,similartorefiningandextraction[3-4- 5]. The importance of OSN is obvious from the fact that one cubic meter of methanol requires 1750 MJ of energy for distillation since the process of distillation is comprised of heating, evaporation, and condensation while OSN can purify the same volume of methanol by consuming 3 MJ of energy [6-7]. Additionally, OSN is a useful technology since it is simpler to use than conventional purification and separationmethods.Themembrane'sporestructure,whichinfluencesbothitsselectivityandpermeance, hasasignificantimpactonhowwellthemembranesperform[8-9].Ingeneral,thetrade-offbetweenflux andselectivityaffectsthemembrane'sperformance.Asaresult,themembranes'fluxandpermeabilityare affectedbythetailoringandtuningoftheirporestructure.Therefore,designinganefficientnanofiltration membranes with ideal porosity is highly desirable. Interfacial polymerization (IP) is highly versatile as it provides a freedom of selection of various monomersfortargetingaspecificapplicationsuchasnanofiltrationandreverseosmosisThepotentialfor organicsolventnanofiltration(ON)toreplacevariousenergy-intensivetraditionalpurificationtechniques, suchasdistillationandextraction,isenormous.[8-9].Despitethefactthatmanydifferentmonomershave been successfully used by utilizing IP to create thin film composite nanofiltration TFC-NF membranes, one of the main limitations of such membranes continues to be the poor selection of closely related comparable nanometer sized solutes. Many efforts are still being made to develop potential monomers with the perfect properties for creating membranes that operate excellently [10-11]. Another strategy is also getting more popular in which different porous additives are added to the TFC membrane either at thesupportleveloractivelayerlevel.Theseadditivesincludecarbonorganicframeworks(COFs),metal organic frameworks (MOFs), hyper-cross-linked porous polymers (HCPs), and natural polymers such as chitosan[12-13-14-15]. However,maintainingthecrystallinity ofsuch additives,particularlyMOFsthat lead to crystalline membranes, is extremely difficult while other additions suffer from aggregation and agglomeration that results in membrane flaws that impair the performance of the membranes [16]. Therefore,changingthechemistryofthereacting monomerduringIPcansignificantlyalterthestructure of the resultant active layers of the membranes. The current study was carried out by using linear aliphatic amines 4A-3P and 4A on a crosslinked PAN support. The study was carried out through interfacial polymerization between either 4A-3P and TPC or 4A and TPC on crosslinked PAN. In comparison to the previous studies where cyclic amines such as piperazine or aromatic amines such as meta-phenylenediamine (MPD) are used, we have used linear aliphatic amines 4A and 4A-3P crosslinked with organic phase containing terephthaloyl chloride (TPC) asacross-linker.TheIPreactionwascarriedoutbetweenamineandTPConacrosslinkedPANsupport. The fabricated membrane was extensively characterized by using scanning electron microscope (SEM), ATR-FTIR, water contact angle (WCA), energy dispersive X-ray (EDX) and elemental mapping . The fabricated membrane was used for OSN applications by using dead-end filtration setup.