Natural resources utilization for the in-house production of fluorescence lipid nanoparticles
Nanotechnology, a transformative force, has steadily gained traction across multiple scientific disciplines, including physics, chemistry, engineering, and biology. It offers unprecedented capabilities, especially in the realm of nanoscale particles, ushering in new paradigms in various applications. One of the most revolutionary applications of nanotechnology is in the pharmaceutical sector. Here, nanoparticles have transformed drug and vaccine delivery systems, offering both efficacy and precision. Among these nanoparticles, lipid nanoparticles (LNPs) have stood out, especially for their role in delivering nucleic acid-based drugs and vaccines. These LNPs are intricate assemblies composed of lipids and nucleic acid complexes, offering an amalgamation of stability and deliverability. Such properties have rendered LNPs as invaluable tools in enhancing therapeutic efficacy while minimizing off-target side effects. The myriad of nanoparticles available includes the likes of silver, gold, and lipid nanoparticles. However, the emphasis of this research lies with lipid nanoparticles, given their widespread success in the pharmaceutical arena. LNPs have showcased their potential in delivering drugs with low therapeutic indices, emphasizing their capability to act as versatile platforms for novel drug development. Recent advances have further expanded the horizons of LNPs, paving the way for novel antisense oligonucleotides, innovative vaccines, and complex lipid nanoparticle formations. Characterizing these nanoparticles is paramount, not only for the development of novel drugs but also to comprehend their in vivo behavior. Their multifaceted nature, stemming from their unique excipients, core-bilayer design, and varying sizes, makes their characterization a critical step in the research and development pipeline.
Automatic Solar Panel Sprinkler Irrigation System
As the global demand for sustainable agriculture practices and renewable energy sources continues to rise, the integration of solar power technology with irrigation systems has gained significant attention. This abstract presents an overview of an innovative solution known as the "Automatic Solar Panel Sprinkler Irrigation System," which combines solar panels and smart irrigation technology to efficiently manage water resources in agricultural settings. The proposed system leverages solar panels to generate electricity and simultaneously operate an automated sprinkler irrigation system. Solar panels are strategically positioned in proximity to crop fields, utilizing photovoltaic cells to convert solar energy into electrical power. This energy is then harnessed to power the irrigation system, providing a sustainable and eco-friendly method for crop hydration. In Solar Power Generation the system consists of photovoltaic panels designed to capture solar energy during daylight. This renewable energy source is converted into electrical power, which is stored in batteries for subsequent use. Automated Sprinkler Irrigation is an advanced control system manages the irrigation process, ensuring efficient water distribution based on crop requirements. Soil moisture sensors and weather data are integrated to optimize irrigation scheduling. In Remote Monitoring and Control, farmers can remotely monitor and control the irrigation system through a user friendly interface, accessible via smartphones or computers. This feature enables real-time adjustments and ensures that water resources are utilized optimally. In Water Conservation the system is designed to minimize water wastage by delivering precise and targeted irrigation, reducing over-watering and the associated environmental impact. In Cost Savings the harnessing solar power, this system reduces electricity expenses, making it an economically viable solution for farmers, particularly in regions with ample sunlight. Using a tracker with an automatic solar panel sprinkler irrigation system can be a smart and efficient way to optimize the system's performance. And the most important thing is that in my prototype it is under the panel and will track the location of the Sun and with that it will lead to the Automatic movement of the panel from east to west and when the evening starts it will go back to its position.
Mattress Ventilation System
One of the worldwide hidden problems with lack of attention is Bedsores. Simply, These are ulcers, that happen on the areas of the skin that are under pressure while lying on the bed for a prolonged time. This can be infected to anyone in the world. The common group who face these bed sores are..... •Elderly patients, •Spinal cord injury patients, •Stroke patients, •Coma patients, •People who have faced accidents Bed sores develop when the blood supply is cut off for more than 2-3 hours to the skin, (Position changing time depends on the patient's condition) The continuous pressure is the cause for that and also the temperature generated between the skin and the bed surface increases the metabolism of the tissues. When the skin temperature increases by 1°C, the risk of bed sores increases approximately 14 times. So, The skin temperature in the range of 29.4°C to 37.1°C is correlated with the tissue damage score. Not only that shearing and moisture are the other considerable factors for this problem. This infection has 4 stages. Sometimes in the 4th stage of the bed sores can cause death.
Non-invasive study of the electrical activity of the brain of various chordate animals
In clinical practice, EEG is used to diagnose a number of neurological diseases and to diagnose epilepsy. But at present, the question of the nature of EEG has not been completely resolved and is of great scientific interest. There have been no studies at all on the non-invasive study of the electrical activity of the brain of the shark superorder, which belongs to the class of cartilaginous fish. By studying the electrical activity of the brain of various gnathostomes, it is possible to obtain an answer to the question of the emergence of rhythms from the point of view of phylogenesis and evolution, and by comparing their EEG with the human EEG, one can identify similar patterns that help in the study of reactions to various influences. During the work, for the first time, EEG indicators of spotted cat sharks, ECG, heart rate and respiratory rate of cat sharks and toads were obtained. In the future, it is planned to assemble a smaller neuroheadset for non-invasive studies of the electrical activity of the brain of small animals (sharks, toads, monitor lizards). This data can be used for evolutionary and medical research. *No animals were harmed during or after the experiments.
AGRO-GUARD:Machine Learning-Driven Plant Real-Time Disease Detection,Clustering and Community Notifications
Agro-guard aims to revolutionize disease identification and community-based projects in the field of agriculture. Integrating Machine learning, Computer vision, clustering, and community-based technology, this project helped farmers to detect their plant disease with their solution and for early warning of plant disease which was spreading in their community which helped in crop management. The research project is divided into three parts.First,Integrating Machine learning to detect and classify plant disease with their solutions.Second,Integrating Density-Based Spatial Clustering of Applications with Noise (DBSCAN),to identify disease and analyze the pattern within agricultural regions.Third,Establishing notification system to notify real-time alerts to farmers about disease spreading in particular region.The research is crucial because it solve one of the crucial problem of our community which is untimely detection of disease.The finding of the research highlight the effectiveness of Agro-Guard framework in early disease detection and community detection.The machine learning models achieved high accuracy in identifying common plant disease and clustering results the pattern in diseases that were very important for notifying the community.The significance of these findings is that it can build powerful system which will overall grow the production of crops and plants due to timely update of the disease prevailing in the community.It contributes in sustainability production of crops and plants which ultimately ensure the good livelihood of farmer.