Two Klatovy copies of Šimon Brixi's Domine ad Ad juvandum me festina and his time
The main goal of this paper was a creation of musical score for the composition from the 18th century Domine ad Ad juvandum in A minor and C major composed by Šimon Brixi. Another goal was finding as much information as possible related to this composition and summarize everything possible that was written previously. Separate parts were transcribed into one partiture. Nevertheless there were difficulties like mistakes in sheet music (corrected according to harmony of other voices), missing beats (replaced by identical parts of score), differences in period station. Hard times also bring on differences of period notation. The resulting musical scores can be directly used for music production, which is schemed for the next year. The second part was researching new or never-published information related to these compositions. Here I describe Š. Brixi´s life. I managed to read out the cause of Šimon Brixi death in a chronicle, which was not in the publication I found. Brixi died of tuberculosis like his son. Transcriptors, J.V.Flaška and J.J.Hoffman, are also mentioned. Lastly the information about sheet music itself and its historical context were described. Another discovery was an identification of watermark on sheet music paper. Assuming the sheet music is truly transcribed in 1742 the Kolinec paper mill watermark on the sheet music paper is the oldest evidence of its use. In this paper I summarized the historical context of the baroque era including social life, art and culture.I mentioned the most important events that were crucial for historical development in Bohemia and especially in the Klatovy region. This context can be useful for today’s musicians who want to understand the historical background and express the composition with full respect to the time of its creation.
DEVELOPMENT OF PAPER-BASED ORIGAMI BIOSENSOR PLATFORMS FOR COLORIMETRIC DETECTION OF BIOCONTAMINANTS
Infectious diseases caused by bacteria from biological pollutants pose a great burden in terms of diagnosis and treatment, and millions of people worldwide die from bacterial infections. Detection of bacteria plays a critical role in clinical diagnosis and control of contamination, but is not accessible due to the high cost, complex devices and equipment required. In the project, an alternative to existing methods, a paper-based biosensor for the detection of model organism E. coli bacteria, which is visible, low cost, easy to use, can be integrated with a smartphone, is based on rapid color change in the exposed environments, drinking and pool water, wastewater, beverage products. platforms were developed. For the specific detection of E.coli bacteria, two different biosensors have been developed that can perform colorimetric detection in a user-friendly origami design, minimizing microchip and processing steps based on antibody-bound PVDF membrane and filter paper-based immunological method. In the presence and absence of target bacteria E.coli, the lowest detection limit of the biosensors obtained by using paper-based platforms that create a distinctive color on them, depending on the concentration, was 0.9x103 bacteria/ml for origami biosensor, 2.7x103 bacteria/ml for microchip biosensor and the widest dynamic linear operating range was calculated as 103-107 bacteria/ml. With the biosensor platforms we have developed, the use of only one smartphone for both qualitative and quantitative, visible results and analysis within minutes constitutes the originality of our project. With these promising results, the biosensors we have developed can also be used for the detection of different biological pollutants, do not contain complex devices and can be easily produced in large scales. We believe that the biosensors we have developed for the detection of biological pollutants in water and beverages, especially in regions where test laboratory infrastructure is not available, will contribute to the literature, public health, health economy and sustainable development goals such as clean water and sanitation, health and quality life, and life in water.
Synthesize Sodium Sesquicarbonate and Increase Yield
In order to recycle disposable diapers, we investigated the conditions where sodium sesquicarbonate (Chemical formula Na2CO3・ NaHCO3・ 2H2O hereinafter called sesqui) precipitates selectively from sodium carbonate and the conditions for high yield. For the selective precipitation of sesqui, we defined the time required for the reaction solution to pass through the sesqui precipitation area in the Na2CO3-NaHCO3-H2O phase diagram (45°C) as Δ t. As a result, we revealed that Δt is involved in the selective precipitation of sesqui, and that we can synthesize sesqui without the expensive addition of L-Arginine as used in a previous research. Also, we proposed the “Stay method”, in which the supply of CO2 is stopped for 30 minutes to the lengthen the Δ t, and found that we could synthesize sesqui selectively even under conditions in which sodium bicarbonate is likely to be precipitated as well. Regarding the high yield of sesqui, the yield was greatly improved by the common ion effect of Na by adding NaOH to the reaction solution, sesqui synthesis by repeated reactions with CO2, and sesqui recovery by adding the anti-solvent ethanol, reaching a sesqui conversion rate of 95%. This means 109 g of sesqui can be synthesized from 100 g of Na2CO3. Moreover, we confirmed that these synthesized samples have almost the same detergency as commercial sesqui. We did a test calculation to reveal the usefulness of this research. First, if diaper recycling technology is put into practical use and all used diaper waste in Saijo City can be recycled, a reduction of 534 t/year of used diaper waste can be expected. This corresponds to a 2.3% reduction in Saijo City's waste output. From the ash that would ultimately remain after being recycled, we expect up to 35.3 t/year of synthesized sesqui using our experimental method. In addition, a CO2 reduction of 8.2 t/year is possible in the process, which is about equivalent to the volume of one gymnasium.
Designing a LiDAR topographic navigation system: A novel approach to aid the visually impaired
The WHO reports 2.2 billion people internationally have a form of visual impairment, with Perkins School of Blind adding that 4 to 8 percent (8.8 - 17.6 million people) solely rely on a white cane for navigation. In an interview by Stephen Yin for NPR, visually impaired interviewees claimed that a white cane was ineffective as it failed to detect moving obstacles (ex. bikes), aerial obstacles (ex. falling objects), and it became physically demanding after a prolonged period. This problem can be solved with a headset that integrates LiDAR technology and haptic feedback to provide a real-time assessment of their environment. Theoretically, the device will determine how far an object is from the user and place it into one of three conditionals based on distance (0- 290mm, 310-500mm, 510-1200mm). As the user gets closer to the object, the haptic will vibrate more frequently. The device has 11 LIDAR sensors, beetle processors, and ERM motors so that when the LiDAR detects an object, the device will send a haptic signal in that area. It not only identifies the existence of an object but it tells the user its relative position with a latency period of approximately 2 milliseconds. When testing the device, a simulated walking environment was made. Ten obstacles were included: five below the waist (72”, 28”, 35” and 8.5” tall sticks) and five above the waist (paper suspended 6”, 10”, 48” and 28” from the ceiling). The white cane detected 4.1 obstacles, whereas the device detected 7.3 on average. The LiDAR navigation system is 178% more effective at detecting objects comparatively. Visually impaired individuals no longer must rely on the white cane; rather, using this device, they can detect small, moving, and aerial objects at a much faster, and more accurate speed.