探討藉由隧道奈米管(TNTs)傳遞Chromogranin-A對神經母細胞瘤細胞的影響及其相關機制
Previous research observed increased TNTs formation between hypoxic and normoxic neuroblastoma cells, aiding hypoxic cell survival. CHGA was identified as a potential factor in this process. This study compared CHGA expression and whether CHGA exists in TNTs in five cell lines, with SH-SY5Y showing the highest levels, followed by SK-N-BE(2)C, while the other three showed lower expression. Future studies will focus on the impact of CHGA on cell survival and its mechanisms.
探討藉由隧道奈米管(TNTs)傳遞Chromogranin-A對神經母細胞瘤細胞的影響及其相關機制
Previous research observed increased TNTs formation between hypoxic and normoxic neuroblastoma cells, aiding hypoxic cell survival. CHGA was identified as a potential factor in this process. This study compared CHGA expression and whether CHGA exists in TNTs in five cell lines, with SH-SY5Y showing the highest levels, followed by SK-N-BE(2)C, while the other three showed lower expression. Future studies will focus on the impact of CHGA on cell survival and its mechanisms.