研究傳統降火氣食品是否具有抗發炎效果
在炎炎夏日總希望來點可以「降火氣」的食品,依據古籍記載某些中藥材具有降火氣的效應,而中醫所謂的降火氣與西醫的抗發炎反應密切相關。本實驗利用巨噬細胞株受到LPS (Lipopolysaccharide,革蘭氏陰性菌細胞壁表面所含有的脂多醣體)刺激後,會分泌發炎介質的現象,再分別加入各項傳統認為可降火氣(以菊花、薏仁、仙草作為樣品)或上火氣(選用龍眼作為樣品)的中藥食材,來評估中藥材對巨噬細胞分泌發炎介質能力的影響。經由實驗,我們發現市售的『降火氣』中藥食材,在適當的濃度下,確實具有降低IL-6、TNF-α 分泌量的能力,但濃度過高時卻會造成細胞凋亡。另外,傳統以水熬煮的方式比冷凍乾燥取得的樣品有更好的降低IL-6、TNF-α 分泌量的能力。 我們期望以此一系列的實驗,來建立篩選『降火氣』食材的抗發炎效用的研究模式,並在後續實驗中可用以篩選出更多具抗發炎效應的中藥材。In summer, people always consider eating some special things to refresh themselves. According to ancient books, there are some Chinese herbal medicines that were recorded to have the function of cooling us down, which is related to anti-inflammation in the Western. Macrophage cell lines can be stimulated by LPS (Lipopolysaccharide) and secrete proinflammatory mediators. Thus, it is often used to evaluate the anti-inflammatory effects of different herbs. In our experiment, we also use macrophage cell lines to test different anti-inflammatory effects between chrysanthemum, Job’s tears and grass jelly. In addition, some Chinese herbs such as longan that can parch us are also tested in our experiment. In our results, we found these herbs that are available indeed have ability to anti-inflame in appropriate consistency; however, high dose does harm to cells. In addition, the samples that are poached in ancient ways have better ability to show the low dose of IL-6 and TNF-α. Finally, we would set up a model to test the anti-inflammatory ability of different herbs that were said to be able to cool us down, and then we could test more herbs in the future.
台北盆地的熱島效應及其對環境的影響
本研究主要是以台北市中心的氣溫觀測站,以及市區外圍東邊的汐止,南邊的屈尺,以及西邊的山佳等三個氣溫觀測站,從1998 年至2004 年的七年期間的氣溫資料中,來探討台北地區的熱島效應現象。這個研究的結果發現,台北市區與周遭鄰近地區確實會因為熱島效應的影響而產生1~2℃的溫差。這個溫差在白天時不甚明顯,在中午過後,便由台北市中心逐漸向郊區遞減,形成類似同心圓狀的分布。溫差最大值發生在夜晚,使得台北地區晚間宛如一座夜晚增溫的城市,同時夏季的熱島效應又較冬季顯著,氣溫又逐年遞升,造成夏季台北市區的高溫屢創新高,將是未來都市發展的危機。This study is focused on the urban heat island effect of Taipei Basin, northern Taiwan. The hourly temperatures of Taipei meteorological station and three rural sites eastern Hsi-Chih, southern Cyu-Chih and western San-Chia, were compared from 1998 through 2004 to illustrate the temperature differences between city center and surrounding country areas. The results show that a difference of 1~2℃ exists between city center and surrounding country areas, indicating the extent of urban heat island effect in the Taipei Basin. The daily temperature contours show a clear high-temperature bull’s eye at the city center during the midnight, implying the high latent heat trapped by the dense and high rise buildings. This phenomenon is not sharp in the high noon due to the reduction of temperature difference between city center and surrounding country areas. The heat island effect is most prominent in the summer than that of the winter. Along with the increasing temperature-difference trend through years, the summer times often experience record-breaking heat waves and pose great risks for the city development in the future.
「從害羞到大方需要多少時間」(環境因子對含羞草開葉時間的影響)
含羞草會因為受到各種不同外界刺激(光照、外力等等),而造成膨壓改變。外 觀上表現出葉片閉合或有葉柄下垂的現象。其中含羞草處在黑暗的環境下一段時 間後,會做出睡眠運動。當它重新暴露於光照之中,將會需要一段時間以恢復原 先葉片張開的樣子。這個實驗是研究不同類型的環境因子(主要是光照和溼度)在打 破睡眠運動之後,對其葉片復原時間所造成的影響。我們針對上述環境因子在不 同狀況時,進行我們的實驗上百次,進一步得到了多項的數據。也在實驗中,為 了精確了解整個恢復的程序,而將恢復程序程序做成書面說明。以下是我們所紀 錄與分析完數據後的結果,以及我們在實驗期間,進行一些不同的實驗嘗試,所 發現不同於表面所見的驚人事實。 The mimosa can accept plenty of stimulation (light, force, etc), which results in the change of turgor pressure, and on outward appearance, it shows the phenomenon that the leaves become closed or that the stalks get pendent. Among the stimulation, the mimosa will undergo nyctinasty when it is left in the dark for a period of time, in order to enable it to be exposed to the light once more, which requires certain time. This experiment is based on how different kinds of elements of the environment (primarily light and hydro level) effects the rehabilitation time after the nyctinasty is broken. A large number of data are gained after experimenting on it for hundreds of times. Steps of habilitation are also made into illustration in writing, so as to understand the whole steps accurately in the experiment. Below are our records and analysis based on the data, including a few special experimental tries during our working time, in which some surprising facts that were discovered are different from what are seen on the surface.
誰能比我更善變???~ 釩鎵磷酸鹽的合成及其結構鑑定
This research tries to find out how changes of weight or proportion of a reactor would affect the type and structure of a crystal. In the experiment, the Hydrothermal reaction was adopted to conduct the syntheses of Vanadium-substituted Gallium Phosphates and try to pick up the single crystal to collect data with SXRD for further illustrating the crystal structure with diamond software to know well its nature. The research result finds out a new type of crystal unseen in the existing literature produced because of the weight changes of C3H10N2, therefore the weight change of a reactor may affect the structure of crystal significantly. In the future, it is expectation that comparison among structures of other Vanadium-Substituted Gallium Phosphates can be made, and the properties of this compound can be measured, and try to find out a brand new type of structure for new exploration by changing the initial reagent.
本研究係透過改變化合物所添加之反應物的比例,以了解反應物比例的改變對晶體的型態與結構的影響。實驗採用中溫水熱反應來從事金屬釩鎵磷酸鹽的合成。並挑取單晶,以X-ray 繞射儀進行數據收集,再以diamond 軟體繪出晶體的結構圖,且進一步得知其性質。研究結果發現,經改變丙二胺的量後,產生不同於文獻上的新化合物,可知改變所加反應物的比例,對於晶體結構有相當大的影響。未來可朝向與其他的釩鎵磷酸鹽做結構上的比較、對此化合物做更進一步的性質測量、改變起始試劑測試,進而得到更新穎的結構形式等部分進行探究。
液滴在我眼前蒸發
本研究的目的在觀察液滴的蒸發過程,探討影響一滴蒸發方式改變的變因。我們利用數位攝影機外加近攝鏡頭,由側面逆光拍攝液滴蒸發過程,並轉錄成電子檔利用電腦協助分析。液滴影像分隔放大投影在方格紙上,以便測量接觸角及高度的變化。結果發現蒸發情形可分為三種:Ⅰ.當接觸角大於九十度時,液滴和界面的接觸線迅速外擴,直到接觸角遞減至90度後定住不動,蒸發終了時,接觸線迅速內縮,留下縮小的實心殘跡。Ⅱ. 當接觸角小於九十度時,接觸線先些微外擴迅速外擴,之後定住不動,直到蒸發終點,液體內縮,留下環狀殘跡。Ⅲ.當接觸角小等於九十度時,接觸線始終定住不變,液滴蒸發後留下原大小的實心班跡。液滴蒸發時接觸角和高度並不是連續變化,而是交互階梯式遞減。本研究的結果可應用在探討噴漆及噴墨印表機的噴墨印刷上。The objective of this investigation is to observe the evaporation of liquid drop and find out the factors that could affect it. A digital camera with micro lens is used to film the process of the evaporation. And a close-up of the sample drop is taken with backlight. The results are analyzed with a personal computer. The magnified images of the drops are projected on grid papers for measuring the changes on contact angles, and heights of drops. We classify the evaporation of a drop into three types: Ⅰ. The contact angle is greater than 90 degrees. At first, the contact line will spread outwardly till the contact angle decrease to the 90 degrees and then be pinned until the evaporation reach its terminal. At last the contact line quickly contract inwardly, and a solid stain remain. Ⅱ. The contact angle is less than 90 degrees. The contact line will spread slightly and then be pinned. At the terminal the liquid contract inward, and a ring-like stain is formed. Ⅲ. The contact angle is equal to 90 degrees. The contact line will always be pinned, and no ring, but spot stain is left. During the evaporation, we discover that the contact angle and the height of the drop do not change continuously but alternatively decrease by steps. The results of our investigation can be applied to the aspects of paint-spraying and jet printers.
化學中的數學與程式設計
When we were learning about organic compounds at school ,there was a unit discussing the isomers of alkane .Our teacher made us practice drawing all the structural formula of the isomers from hexane to nonane .We were much interested in the subject .However ,we often missed or duplicated some isomers .Thus , we began to think if it is possible to find a way by developing programs to let the computer calculate the exact number of the isomers of alkane . After discussion ,we set up a complete coding system .We numbered the isomers in the way that computers could decode and then wrote them in C language. Through computer execution ,the numbers of the isomers from C1 to C20 all match those on the reference website. According to the same concept , we also find a way to calculate the number of alkane with one substituted group . In the future,our goal will be focused on the research of multi- substituted alkane and cyclokane. In addition , the ionic crystal accumulation model are so variable. Take the double face-centered accumulation of NaCl for example, when the ion pairs are extended to the infinity , the potential energy of attractive field will approach a constant which is named as the Madelung Constant. We also managed to write a computer program with C language to approach this convergence with three models, including cube , octahedron , and sphere . The result turned out to be that the data of the sphere was less stable . In the other two models , when “n” is up to 43 layers , the data is identical with that on the reference website to the eight decimal point . 在學校裡學習有機化合物有關烷類異構物這個單元,老師讓我們練習畫出己烷~壬烷的所有異構物結構式,這引起我們極大的興趣!但常一不小心就漏掉或多出幾個,我們開始思考:能不能找到一個方法並設計成程式,讓電腦執行以找出烷類異構物?經過討論,我們建立了一套完整的編碼系統,將各異構物以電腦可解讀的方式編號,並以C 語言寫成程式。透過電腦執行,各碳數化合物自C1至C20都與參考網站吻合。依相同觀念,我們也設計出烷類含一個取代基的異構物數目。將來努力的目標為:多取代基及環烷類之研究!另外,離子晶體堆積模型變化多端,以NaCl 雙面心堆積為例,其引力場位能,當離子對延伸至無限大時,這個值將趨近於一個常數,又稱為馬德隆常數。我們嘗試以C 語言設計電腦程式,用三種模型(正立方體、正八面體、圓球)來逼近並求得這個收斂值。執行結果是:圓球數據較不穩定;而另二種模型到n=43 層以上,其數值大小與參考網路上的數值,在小數點以下8 位完全相同。
國王的海市蜃樓
在夏日的午後,在炎熱的柏油路面上很容易可觀察到遠方的 路面上,出現如鏡子般的倒影,看起來彷彿前方有一灘水,但當 我們向前進一些時,倒影卻突然消失了,這個現象,一般稱為海 市蜃樓。 一般解釋海市蜃樓的成因,都是由於在上層的低溫空氣,和 在下層靠近路面的高溫空氣,因密度的不同,以致於折射率的漸 層差異,繼而產生全反射。 但我們觀察發現,地面與上層空氣的溫差,並非柏油路面上 假積水現象及倒影出現的必要條件;反而和入射光的角度、路面 的平坦程度及路面的性質有關。我們提出了粗糙面在入射光的入 射角接近90度時,可發生單向反射的模型。並由實驗來驗證假積 水現象及倒影主要的成因是「柏油路面的單向反射」而非「空氣 的折射與全反射」。 Under the scorching sunshine, we can see the reflection on the tarmac in the distance just like a water puddle on the road. And the water also reflects the people and object nearby. But, in fact, the tarmac road over there is very hot and dry. Therefore we call the phenomenon as the “false water puddle on the tarmac.” According to the textbook , the main reason for “false water puddle on the tarmac” is that the temperature difference leads to the refraction of the light and causes the phenomenon. However, from our observation, the theory still can’t explain some phenomenon, For example, the “false water puddle on the tarmac” remains to appear when the wind blows fiercely. Even with little temperature different at night the phenomenon is still obvious. Therefore, in our opinion, the temperature different of the air is not a necessary condition of “ the false water puddle on the tarmac.” We bring up the model to explain the phenomenon that when the incident angle of the light approach 90 degrees, the light will result in one-way reflection. According to the model, furthermore, we make experiments at midnight and at dawn. The result of the experiment assures us the hypothesis of the model, Consequently, we hold the ideal that the main condition of the “false water puddle on the tarmac.” Is not because of the refraction and the total reflection but because the light reflects off the road and result in the one-way reflection on the tarmac road.
周轉不靈(汽車過彎翻覆原理與對策)
「翻車」事件令人怵目驚心,輕則車毀,重則人亡。減少翻車事件,可減少悲劇的發生。而翻車絕大多數均發生在轉彎的路段,且伴隨著超速發生。因此,本研究乃針對汽車過彎行駛,探討其翻覆的原因以及改進之道 · 本研究乃利用實驗分析法以及理論驗證法進行研究,實驗中變化不同的汽車質量,車軸寬、車身高以及車軸寬/車身高,質量重心寬、高以及寬/高、傾斜度以及迴轉半徑等九種參數 · 於自製的紅外線偵測變頻式可調迴轉模擬機上以八部模型試驗車測試其翻覆轉速,並換算為翻覆速度後逐一分析討論之。經由實驗結果,本研究得到以下結論:一、汽車轉彎翻覆與離心力有關,當離心力大於臨界側向推力時,汽車即翻覆。臨界側向推力公式為 F = mg ( tanθ + K?) / ( l -K? tanθ ) 二、最大容許車速平方與轉彎半徑及質量中心寬高比相乘積成正比;而在定車速下,飲小客許轉彎半徑與質量中心寬高比成反比.前述各項皆與質量大小無關.三、提高轉彎路面傾斜度對防止汽車翻覆有確實的效果。而最佳的過彎防止翻覆方法是降低車行速度,提高轉彎半徑,增加路面外側傾斜度,以及提高汽車質量中心寬高比”四、汽車過彎不致翻覆的最大極限速度 Vc 以及最小轉彎半徑rc分別為 vc=〔 rg ( tan θ + K ?)/ ( l 一 K ? tanθ ) ]; rc =( V2 / g ) ( l 一 K?tanθ ) / ( tanθ + K? ) 五、本實驗所設計紅外線偵測變頻式可調迴轉模擬機,可有效的模擬汽車過彎翻覆,適用於中等學校物理、力學等學科的實驗課程。The accident of overturning a car always results in both destroying the car body and the death of the people. This project is to investigate what factors would have an effect on overturning a car and how to prevent a car from overturning.This project explores the factors by varying the mass of the cars, the distance between axes, the height of the car body, the ratio between the axis distance and the car height, the central gravity, and the declination. We test and record different overturning rotating speeds of eight model cars by a self-made adjustable simulator with a varying frequency infra-red detector. According to the experiment, the following results are obtained. I. The overturning occurrence is as a result of the eccentric force over the critical lateral force. The critical lateral force is F=mg(tanθ +K?)/(l—K?tan θ) 2. The square of allowable maximum speed is in proportion to the product of turning radius and ration of width to height for the center of mass; however, the allowable minimum turning radius is inversely proportional to the ration of width to height for the center of mass under constant vehicle speed. The above inference is independent of the mass of vehicle. 3. Increasing the declination can prevent a car from overturning. 4. The maximum speed for a car turning without overturning is Vc. The minimum turning radius is r. Both are expressed as follows:Vc=[rg(tanθ +K2)/(1—K?tanθ );rc=(’V2/g)( I —K?tanθ )/(tanθ +K?)5. The self-made adjustable simulator with a varying frequency infra-red detector can be used in the experiments of the middle school science curriculum.