高中各學期成績與指定考科相關性
在升學主義越來越興盛的社會中，考試成績成為人人關心的重點，這\r 次研究就是藉由數理資優班同學的各學期在校成績和指定考科成\r 績，透過迴歸分析，找出各學期成績與指考成績之間的關係，並利用\r 圖表來解釋各種科目在各學期的課程，在高中三年所學的重要性，在\r 藉由此結果，希望能對目前老師的教育重點及學生學習方式能有所幫\r 助，亦可了解學生在高中求學過程中，哪些階段對指考成績較有正面\r 影響，進而強化該學習階段，以有助在指定考科時能充分發揮所學。\r \r In a society that emphasize on degrees, examination scores become the\r spotlight, and the ultimate goal for a high school student who had worked\r so hard for three years is to achieve high scores in the J.C.E.E. In the\r three years of high school, each subject has different topics each semester,\r but which semester has the most decisive effect on the J.C.E.E. score?\r This research is to study the effect of each semester on the J.C.E.E. by\r analyzing the grades of a science and math talented class in Senior High\r School using Regression analysis to find out the connections between\r term grades and the J.C.E.E. Then finding out which term grades had the\r most decisive effect in each subject. By using the result, we hope it can\r help teachers in their teaching and students in their learning. Also, it can\r provide the information about which stage in high school has positive\r effects on J.C.E.E. grades, therefore enabling students to emphasize on\r that stage in order to perform well on the J.C.E.E.
利用雷射光實驗研究液的折射率梯度
溶液和溶劑置於同一容器中，當溶質向上擴散時，會形成濃度梯度及折射率梯度 dn/dy，且dn/dy 對高度y 的關係圖會呈現隨著高度改變的現象。 半徑r 的Ｄ形容器，下方置溶液，上方置溶劑，以雷射光照射容器的平面部份時， 雷射光沿著法線出射，受折射率梯度的作用而向下偏Ζ距離，a 為容器至屏的距離， 得到dn/dy=Z/ar 的關係式；改變雷射光的高度y 可得dn/dy 圖。 以硫代硫酸那作實驗，其dn/dy-y 圖為以原始界面為對稱軸，因其擴散係數不隨濃 度改變；甘游水溶液的dn/dy-y 圖呈現不對稱，圖形的極大值往甘油方偏，主要係因 為甘油的擴散係數隨濃度的增大而減少。 我們成功第把不同時間對同一溶液的實驗結果予以模型化，得到的dn/dy-y 曲線隨 時間改變，並發現該曲線所涵蓋的面積為定值。 雷射光經光柵再照射半圓筒，可直接測出各高度的折射率，量出y、 dn/dy、n、及濃度可算出擴散係數。The mixing between a pure liquid and a solutionin a vertical column produced a concentration gradient , which in turn produced the refractive index gradient . As the solute particles diffused upward into the pure liquid , a gradient was generated because of the varying solute concentration . The plot of the refractive index gradient versus vertical position y (dn/dy vs y) is found to vary with time . A D-shape container of radius r is partly filled with a dense solution , and partly filled with solvent which is on the top of the solution. When laser beam pendicularly enters the flat surface of the container, the outgoing beam strikes the container at a normal incidence , and is deflected down a vertical distance Z by the refractive index gradient . We can get dn/dy=Z/ar , where a is the distance between the container and the screen . By changing the vertical position (y)of laser beam , we can get the plot of dn/dy vs y . We have successfully modeled the time dependent experimental gradient curves on the same solution . The area beneath the trace of dn/dy vs y at different time is found to be constant . Additionally, with a grating at the center of the semicircle, we can measure the index of refraction n and get the plot of n vs y. The diffusion coefficient D of the solute can be calculated using the plot of dn/dy,y,and time t.
模擬複雜系統的演化
複雜系統廣泛地存在每個人生活的周遭，儘管這些系統在表象上有明顯的差異，卻不約而同的都呈現出臨界現象。一個簡單的物理概念卻能廣泛地使用在許多不同的場合當中，這是令人始料未及的。這份報告在尋找，是什麼原因導致這許多似乎與物理沒什麼關聯的系統，都呈現出臨界現象？以及這類系統是如何演化的？臨界現象在系統的演化歷史中，又是扮演怎樣的一個角色？一開始，先介紹臨界現象在實際系統中表現的形式，在這以文字系統作為範例。接下來，進入思考的階段，猜測系統個體間存有的關聯性，提出如何影響的假設，並建立模型。從模型結果，可以了解複雜系統隨時間演化的趨勢改變，並發現臨界現象在系統中扮演的角色以及代表的意義。這份報告有三項結論：1. 臨界現象在複雜系統中呈現的形式 2. 模型結果與實際系統十分相似 3. 臨界現象代表著系統的穩定態。The theory of Scaling Law and Universality was originally used in researching Critical phenomena, and now we find it existing in our normal life. A simple physical concept can be used extensively in different courses. This study try to find out the relation between individuals which causes Critical phenomena appear in such different courses in our normal life, and figure out the effect time brings about. To begin with, we introduce the sights of Scaling Law and Universality by exploring the formation of complicated system. Facing a complicated word system as a real example, we observe an extraordinary phenomena, and find out the Universality and Scaling Law in different kinds of linguistics. In the main part, to think further, what’s the relation between the individuals that leads to Critical phenomena? We will give hypotheses and build a model to simulate complicated system from the view of Universality, trying to find out the cause of the interaction of complicated system. From this model, we could understand: When a complicated system evolves with time, the Critical phenomena will naturally occur in this system that could be considered as dynamic equilibrium. From this study we found out(1) The Universality and Scaling Law in complicated systems, here we use linguistics as an example.(2) Under the hypotheses, the simulation is almost as same as the real result of linguistics system.(3) Time plays an important part in the Critical phenomena which can be found in many different complicated systems, and Critical phenomena symbolize a stable state of such systems.
Tamarind(Tamaridus Indical.)Seed Coat Extracts As Coconut Oil Antioxidant
After short period of storage the coconut oil at room temperature we found that it becomes rancid. The oxidizing flavor is disgusting and causes economic loss. Some chemicals are used to prevent the oxidation of coconut oil but they are expensive and may be harmful to consumer’s health if used daily. Moreover, they are not suitable for homemade coconut oil and residual waste from the process may be environmental toxic. The present work thus aims at extracting substances from local plants and used as antioxidant for coconut oil. Seven kinds of local Caesalpiniaceae plants in Eastern Thailand namely Tamarind (Tamaridus indica L.), Peacock flower Caesalpinia pulcherrima L.), Flame tree (Delonix regia L.), Golden shower (Cassia fistula L.), Siamese cassia (C. siamea Lamk.), Candelabra bush (C. occidentalis L.), and Copper pod (Peltophorum pterocarpum DC.) were used. Ten grams of seed coats were mixed with 50 ml of the distilled water and 95% Ethyl alcohol (1:1) mixture in a closed container. The mixture was heated in a water-bath at 60 ℃ for about 2 hrs. and then kept in 10 ℃ icebox about 2 hrs. The mixture was then filtered and the filtrate was heated in an hot-air oven at 80 ℃ for about ? hrs. Ten ml of coconut oil was added with 0.5g of the extracts and kept at room temperature for 5 days. The pH and peroxide value (using the Iodometric titration method) of the oil were measured. It was found that the coconut oil with the Tamarind seed extract had the lowest peroxide value and was selected. Next the suitable amount of the Tamarind extract was studied by adding the extract to 10 ml coconut oil at 0-7% (w/v) and the contents were kept at room temperature for 5 days. The result showed that the 3% (and more over) Tamarind extract had the lowest peroxide value. Then the coconut oil with 3% Tamarind extract was kept at room temperature for 30 days. The pH and peroxide value were measured every 5 days. It was found that the oil could be stored for 25 days without significant change in pH and its peroxide value was less than 10 milliequivale n t oxygen per kilogram oil according to FAO/WHO (Codex) standard .Therefore, Tamarind seed coat at 3% could be used to retard the coconut oil oxidation for 25 days. This work presents the applicable use of plentiful local plants such as Tamarind seed, which is normally discarded, as an antioxidant for coconut oil.
台灣不同世代A 群鏈球菌對紅徽素抗藥性之研究
A total of 64 nonduplicate isolates of erythromycin-resistant (MIC, >1 μg/ml) Streptococcus pyogenes collected from 1979 to 2003 in Taiwan were evaluated. They were collected from three cohort period: 1979 –1989, 1990-1999 and after 2000. The in vitro activities of 10 antimicrobial agents were determined by the agar dilution method. Penicillin, cephalothin, cefotaxime, vancomycin, and ofloxacin were shown to be active against S. pyogenes isolates (100% sensitive). Erythromycin and azithromycin both had poor activities (MIC50s, 16 and >128 μg/ml, respectively; MIC90s, >512 and >128 μg/ml, respectively). The activities of tetracycline, clindamycin, and chloramphenicol against a significant number of these isolates were also limited. Among the 64 S. pyogenes isolates, 58% had constitutive resistance [cMLS], 40% had an M phenotype and 2% had an iMLS phenotype (inducible resistance [iMLS]). A substantial upsurge in the incidence of M phenotype erythromycin-resistant isolates was found with time for S. pyogenes (10% in 1979–1989, 48% in 1990–1999 and 65% after 2000). The erythromycin resistance genes in 64 isolates of the different cohorts were investigated by PCR. All cMLS phenotype isolates tested had ermB gene. The M phenotype isolates had only the macrolide efflux (mefA) gene. This study shows the secular changes of increasing susceptibility of S. pyogenes isolates to both erythromycin and clindamycin in Taiwan. The mechanisms of erythromycin resistance have changed from the predominance of ermB gene (cMLS) to mefA gene (M phenotype). 本研究是探討台灣自1970 年代末期以來不同世代A群鏈球菌菌株對紅黴素的抗藥性及抗藥基因特徵的演變。研究者收集台灣二十年前(1980 年代前後，第一世代)、十年前(1990 年代，第二世代)、)及最近(2000 年以後，第三世代)之A 群鏈球菌菌株共64 株，利用抗生素圖譜和雙藥錠擴散測試及聚合?連鎖反應(PCR)、和脈衝式膠體電泳研究A 群鏈球菌對紅黴素抗藥性的表現型及基因型特徵。結果發現第一世代的A 群鏈球菌對紅黴素最小抑菌濃度(MIC)值相當高，幾乎都是>512 μg/ml，90%為多重抗藥菌株。第二世代則相對有降低，在第三世代此現象更明顯，多重抗藥菌株為30%。在雙藥錠擴散測試結果，從第一世代來看cMLS 佔大多數(90%)，M 型佔10%；第二世代cMLS 及M 型相當分別佔52%及48%；第三世代主要為M 型佔65%，cMLS 佔30%，iMLS 佔5%。利用PCR研究紅黴素抗藥性基因發現所有cMLS 菌株皆有ermB 基因，所有M 型菌株皆有mefA 基因，iMLS 菌株則有ermTR 基因。由本研究顯示在台灣A 群鏈球菌對紅黴素之抗藥性隨著不同世代有逐年改善之趨勢，由MIC50的降低可看出，菌株對紅黴素的敏感性提高，可為臨床治療之參考。
Salinity effects on Duckweed growth
The purpose of this research was to investigate the most favourable salt concentration that promotes growth in the Lemna minor plant. Lemna minor, commonly known as lesser duckweed, is found growing among other aquatic plants or massed together in still or slow moving fresh water, such as ponds and lakes, in warmer regions around the world.
Isolation and Expression of an Eoinephrine-Synfhesizing Enzyme (PNMT) from Entamoeba Parasites
Entamoeba histolytica is a protozoan parasite known to cause infectious colitis and amoebic dysentery in humans. Its life cycle consist of two parts: the infectious cyst stage and the multiplying trophozoite stage. Epinephrine, a neurotransmitter in vertebrates, is released by the trophozoites during the process of cyst formation. The addition of epinephrine to in vitro cultures of amoebas causes them to encyst, and addition of compounds that prevent epinephrine’s activity inhibits encystations. Therefore, epinephrine plays a critical role in encystation in vitro. An understanding of the molecular intricacies of epinephrine-induced encystations may allow for pharmacological manipulation of epinephrine metabolism to control cyst formation in vitro. Drugs that either prevent cyst formation or induce it before a large amoebic population is present would result in the release of fewer cyst forms of the parasite, reducing parasite transmission from person to person. Although trophozoites release epinephrine, it is no known if E.histolytica synthesizes epinephrine or extracts it from the growth medium. Phenylethanolamine N-methyltransferase(PNMT) is the enzyme that catalyzes production of epinephrine norepinephrine. This study aims to determine the source of epinephrine by determining if E.histolytica contains a PNMT-type enzyme. PNMT amino acid sequences from several higher organisms were compared to identify conserved regions of the enzyme. These conserved amino acid sequences were then used to search for similar sequences in a database containing the recently sequenced amoeba genome. A PNMT-like gene was found in the E.histolytica database and cloned in bacteria. Yeast cells containing the cloned E.histolytica PNMT gene expressed PMT enzyme activity. This suggests that E.histolytica produces its own epinephrine, and is the most evolutionarily ancient eukaryote shown to do so. The use of inhibitors against PNMT activity is under investigation.
從小玩意探討大問題－磁浮隔空旋轉器的轉動情形與磁場變化之研究
磁浮隔空旋轉器是由一個旋轉軸和底座構成，利用兩者間相互排斥的磁力， 產生隔空漂浮的效果。本研究首先對旋轉軸的結構加以分析，並設計啟動裝置， 探討啟動電壓、旋轉軸重量及底座磁力等因素對漂浮轉動的影響。 我們分析維持旋轉平衡的各種作用力，並探討旋轉軸重心位置與摩擦力的關 係，以驗證我們的分析結果。此外，我們也利用自行設計的啟動裝置，提供穩定 的初始轉速，探討旋轉軸重心位置不同時，持續轉動時間的變化，進一步驗證所 做的分析。 為了瞭解磁場在旋轉軸漂浮過程中發生的變化，我們設計了支架把空間座標 化，再以高斯計測量出各點的磁場，獲得各平面的磁場強度分佈圖。配合磁力線 分佈圖與所測得的磁場強度分佈圖，我們以一個嶄新的分析模式，將抽象的磁場 概念具體化，使我們對旋轉軸放置前後及磁力與重力平衡時的磁場變化，更深入 的了解，同時也發現磁場強度會隨距離的增加而減弱。 最後我們在旋轉器上裝置感應線圈，經由旋轉實驗測得感應電壓的存在，證 明旋轉器轉動時，磁場會產生變化。 經由對磁浮隔空旋轉器的探討，我們得以了解它的漂浮原理、磁力與摩擦力 間的平衡關係，以及旋轉前後磁場變化。The Magnetic Floating Spinner(MFS) is composed of one spinner with a magnetic base. The floating effect of the spinner is caused by the interaction between the two opposite magnetic fields. We first analyzed the detail structure of the MFS, and then designed a starter to rotate it. Later, we studied the effect of starting electric potential, the weight of the spinner and the magnetic force of the base on the floating movement. We presented an explanation for the forces that maintained the floating of the spinner and, to support that, we studied the friction force with the position change of the spinner gravity centre. We also used the starter designed by us to provide a stable initial rotating force and analyzed the relationship between the change of gravity centre position and the duration of rotation. In order to understand the magnetic field change during floating movement, we designed a spatial frame to coordinate the spinner that floated above the base. We measured the surrounding magnetic force with the Goth’s apparatus and conducted a magnetic force distribution diagram. According to this diagram and the line of magnetic force, we therefore provide a brand new analysis model , which bring the abstract concepts of the magnetic field into a concrete theory. This research not only brings us to understand the magnetic field change of the spinner before and after its placement over the base and the balance between the magnetic and the gravity force, but also reveals that the magnetic force will wane with the increase of distance. Finally, we placed an induction coil by the spinner to detect a voltage change during spinner movement. This is an evidence that the magnetic field will change during the spinner movement. Through the study of MFS, we can now understand why it floats, the balance between magnetic and friction force, and the change of the magnetic force before and after the spinner movement. MFS = Magnetic Floating Spinner