Wildfires have become increasingly frequent and severe due to global climatic change, demanding improved methodologies for wildfire modeling. Traditionally, wildfire severities are assessed through post-event, in-situ measurements. However, developing a reliable wildfire susceptibility model has been difficult due to failures in accounting for the dynamic components of wildfires (e.g. excessive winds). This study examined the feasibility of employing satellite observation technology in conjunction with artificial neural networking to devise a wildfire susceptibility modeling technique for two regions in California. Timeframes of investigation were July 16 to August 24, 2017, and June 25 to December 8, 2017, for the Detwiler and Salmon August Complex wildfires, respectively. NASA’s MODIS imagery was utilized to compute NDVI (Normalized Difference Vegetation Index), NDWI (Normalized Difference Water Index), land surface temperature, net evapotranspiration, and elevation values. Neural network and linear regression modeling were then conducted between these variables and ∆NBR (Normalized Burn Ratio), a measure of wildfire burn severity. The neural network model generated from the Detwiler wildfire region was subsequently applied to the Salmon August Complex wildfire. Results suggest that a significant degree of variability in ∆NBR can be attributed to variation in the tested environmental factors. Neural networking also proved to be significantly superior in modeling accuracy as compared to the linear regression. Furthermore, the neural network model generated from the Detwiler data predicted ∆NBR for the Salmon August Complex with high accuracy, suggesting that if fires share similar environmental conditions, one fire’s model can be applied to others without the need for localized training.

奈米氣泡的大表面積比，表面帶負電，可以在水中停滯很長的時間等特性使得奈米氣泡水溶液異於一般氣泡水溶液。測量奈米氣泡水溶液的導電度，可得知水溶液的電荷密度，超聲處理時間可改變奈米氣泡水溶液的電荷密度，進而改變奈米氣泡水溶液的折射率、表面張力、以及黏滯係數。 利用兩個不同功率的超音波震盪儀(100W,43KHz；200W,40KHz)超聲處理氮、氧、和二氧化碳等三種氣體，震盪時間5分至30分，可以得到不同導電度的奈米氣泡水溶液。用自製的導電度測量器測量奈米氣泡水溶液的導電度；測量氯化鈉水溶液的導電度，用來和奈米氣泡水溶液的導電度做對照比較。 實驗探討超聲處理時間、水溶液的溫度、外加磁場的大小對導電度的影響；以及奈米氣泡水溶液的導電度對奈米氣泡水溶液的折射率、表面張力、以及黏滯係數的影響。

The main goal of this study was to address a variety of topics concerning the role of the Ih current in HCN channels of SHANK Wild-Type and Knock-Out Thalamus Neurons (as described further below). This research explored the cellular effects of sedation (like Dexmedetomidine) and laser light stimulations on the Ih current of neurons, as well as discovering novel biomarkers for detecting Autism Spectrum Disorder. This study also showed that methods (like utilizing laser therapy with and without various photosensitizers) have the potential in raising depressed Ih currents of SHANK Knock-Out neurons.

My thesis focuses on studying Cretaceous microfossil specimens from the excavation of former brickworks in Štíty, especially foraminifera. In the theoretical part, I have covered the structure of the Bohemian Cretaceous Basin area, especially Bystřice Lithofacial Development. I have also processed previous paleontological researches from the locality. Emphasis was placed on field research and subsequently on laboratory research of the site. I have examined the present state of the location and gathered samples of silt clay containing a wide variety of fossils. I have acquired the microfossils, determined them, and ordered them systematically. The most important part of the thesis is the systematic and palaeoecological processing of the collection of microfossils from the locality. The thesis continues the research of the last year of SOČ, where I have gathered a collection of fossil macrofauna, flora, and ichnofauna. My collection is supplemented mainly by benthic and planktonic foraminifers. I have confirmed that the specimens found are typical representatives of marine fauna belonging to the Upper Cretaceous Coniacian. The paleoecological characteristics of the locality correspond to a nutrient-rich shallow-water environment, occasionally disturbed by storm waves.

¬生物光伏電池(BPV)是一種利用光合自營生物進行光電能量轉換的發電裝置。本研究利用共生菌G76創造不須補充培養基的固態複合型BPV。我們以陽極只含小球藻的BPV為控制組(X-C)，發現在實驗開始24小時之後，BPV電壓開始隨著光照週期產生規律變化，前三個光週期電壓高峰平均值為116.23±2.92 mV, 谷底平均值為87.96±4.48 mV，波動幅度28.27 mV。實驗組為陽極有小球藻與共生菌G76的複合型BPV (X-CG)，同時期電壓高峰平均值為109.23±2.45 mV, 谷底平均值為100.63±0.9 mV，波動幅度8.6 mV。與X-C相比，添加G76會使電壓高峰下降6.02%，但提高谷底電壓14.4%且縮小電壓波動幅度69.58%。目前X-CG已運轉超過1032小時，電壓高峰為95.2mV，衰減幅度19.35%。同時期控制組X-C電壓高峰已下降至61.1mV，衰減幅度90.22%。實驗過程中我們發現在X-C及X-CG組別運作73小時後, 在陰極區都出現了紫黑色微生物(PB1)，同時這些被汙染的BPV的電壓明顯比其他組別更高，將BP1單獨培養並引入陰極後(P-CG), 此一BPV的電壓高峰平均值高達179.3±3.66 mV，谷底平均值則為162.37±1.38 mV，都比X-CG組提高近六成。更重要的是X-CG與P-CG分別能保持日間電壓的92.13%與90.56%，都是非常穩定的BPV。 由以上結果可知, 將共生菌G76加入BPV陽極能提高日夜間的供電穩定度並延長裝置使用壽命，而將PB1引入陰極則能使BPV電壓提高六成以上。若能進一步優化應用這些共生菌, 此種低成本複合型生物光電轉換裝置將有潛力建構出一套不須儲電系統的太陽能發電系統。

本研究考慮的主要問題： 若非常數之連續函數f滿足∀m∈N,∃P(x)∈C[x] s.t.f(mx)=P(f(x))，其形式應為何？ (一)、若考慮函數範圍為解析函數，則f(x)的形式必為下列三者之一： (1).axn+b (2). akx^n+b (3). acos⁡(kxn)+b ，其中a,b,k∈C、n∈N (二)、若將考慮函數範圍改為：連續函數f:[0,∞)→C，則f(x)之形式必為下列三者之一： (1).axk'+b (2). akx^n+b (3). acos⁡(kxn)+b ，其中a,b,k,k'∈C、n∈N、Re(k' )>0 (三)、若將考慮函數範圍改為：連續函數f:(0,∞)→C，則f(x)之形式必為下列四者之一： (1).alogx+b (2).axk'+b (3). akx^n+b (4). acos⁡(kxn)+b ，其中a,b,k,k'∈C、n∈N 在本篇的最後，我們也將N的角色以其他正實數子集取代掉以推廣結果。

根據世界衛生組織的統計，胰臟癌高居全球癌症死亡人數第四位，亦為臺灣十大癌症死因之一，為最具侵略性、致死性及預後不佳的癌症。HER2為調控癌細胞增生重要致癌因子，在胰臟癌患者大量表現，其在乳癌細胞中可磷酸化並穩定負責調控組蛋白甲基化的EZH2蛋白表現；而GOT2已知在粒線體內調控麩醯胺酸(glutamine)代謝產生-ketoglutarate，並參與氧化磷酸化幫助胰臟癌生長。 本研究探討HER2/EZH2訊息傳遞途徑是否影響GOT2抑制對胰臟癌細胞之死亡作用，以及HER2/EZH2是否藉由甲基化GOT2調控glutamine代謝與malate-Aspartate循環，找尋出HER2是否藉由EZH2調控GOT2活性而參與癌細胞glutamine代謝反應，觀察HER2、EZH2、GOT2訊息傳遞途徑。 研究結果發現細胞生長作用與EZH2表現較HER2表現具有相關性，並證實EZH2與GOT2確實存在交互作用關係，透過EZH2與GOT2結合並甲基化GOT2而調控其作用，增加活性表現與抗藥效果，顯示EZH2與GOT2參與胰臟癌細胞glutamine代謝機制重要角色。

This underwater remote operating vehicle (ROV) is designed with and without tethered operation. The operator can control the ROV from the real time first-person view in graphical user interface combined with sonar and object detection function when the tether is attached to perform search and rescue. The control tether with fiber optic lighting cable establishes a guided link medium between the possible search victim location and the rescue team. When the tether is detached, rapid deployment by a predefined set of instruction to achieve further operation range. The intelligent technologies of signal processing were used for object recognition, collision detection and sonar scanning data to enhance underwater operation. Autonomous driving is based on software development with limited capability to run in unrestricted open areas. We have achieved the design intent and confirmed the performance data in the laboratory boundary conditions.

在植物中，對於外在威脅能有效進行防禦一直是個非常重要的課題，而此實驗在探討植物彼此間經由根部傳遞的防禦訊息與生理防禦機制。 利用鹽刺激使其根部分泌出AtCAPE1胜肽進行防禦訊息的傳遞，以證實阿拉伯芥防禦訊息確實可經由根部進行彼此的溝通，且可利用擁有正常基因的植株提升突變株的防禦能力。 結合AtCAPE此種植物體內少有被發現的胜肽進行實驗，並提供了許多延續實驗，為植物防禦系統闢出一條大道。

Alzheimer’s disease (AD) is a neurodegenerative disease in which current diagnostic tools are invasive and lack the ability to diagnose early-onset dementia. Current antibody-based diagnostic tests for neurodegenerative diseases require invasive measures such as a lumbar puncture, and lack specificity to biomarkers that are found in both healthy individuals and patients with AD. In this project, a design for a carbon dot(CD)-bound bispecific antibody is developed for the minimally- invasive diagnosis of AD. The molecular probe can be easily synthesized with a specificity to amyloid- beta (Aβ) oligomers as it distribution and abundance in the brain suggest they are better predictors of disease progression and are present in the early-onset of the dementia. The bispecific antibody conjugated to the CD displays a low affinity to transferrin receptors (TfRs) which allows the probe to cross the blood-brain barrier via receptor mediated transcytosis leading to a minimally invasive diagnosis. A synthesis technique was developed to conjugate the bispecific antibody to the CD. As a proof of concept, this technique was used to couple bovine serum albumin (BSA) to CDs. The structural and optical properties of the CDs were observed. By synthesizing a novel carbon dot conjugated specific antibody that emits light at a specific wavelength in the near-infra red region, the molecular probe displays optical properties suitable for the minimally-invasive diagnosis using fNIR- spectroscopy.