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四等獎

大富翁中的密秘—機率

記得小時候常玩大富翁,在走步數之前常要由擲骰子來決定。又在上國中之後學到了有關機率的問題,所以讓我想起此事,想藉由此次的科展對大富翁內的機率做一番徹底的研究與了解。

颱風遇到山~談地形對侵臺颱風風速.雨量的影響

去年(民國九十年),我們在國中地科課本第六章「多變的天氣」中看到一段不懂的話:「颱風移到高緯度的海面以後,也會因低層水氣的供應變少變弱消失。」(104頁第二行)請教老師之後,疑惑未解。師長們幾番鼓勵之後,我們這群對大氣現象原本就充滿無限好奇的國中生便想試試能否一探問題真相,想到能夠挑戰學生心目中至高無上的課本,我們真的是非常興奮!\r 經過數週的資料蒐尋與交叉討論之後,我們發現這並不是件容易的事,事情並非我們想的那麼簡單。於是,在大家冷靜沉澱 想法之後,我們便把焦點放在颱風與地形的交互作用上,先從難度較低的項目開始學習。

無尾翼飛行器之穩定與控制

無尾翼飛行器(Tailless Aircraft)在軍事上的價值極大,且對於目前正在起步的微飛行載具(Micro Air Vehicle)而言,亦是值得嘗試與投資的。然而,由於無尾翼飛行器缺乏用以平衡的水平尾翼,造成其靜態的不穩定,即使設法提高靜態穩定特性,但其氣動力阻尼低、穩定性仍舊不佳。操縱上更是困難,在飛行穩定性與控制系統設計上極其挑戰性。本研究目的在探討無尾翼飛行器之穩定性與控制技術,改善其先天之不穩定特性,考慮之項目有縱向靜態穩定性、動態穩定性、控制面與組件配置等因素等進行詳細之探討。首先,找出了適用於無尾翼飛行器之Reflex翼形,接著建立無尾翼飛行器之非線性縱向動態模式,然後針對一翼展8Ocm之小型飛行器進行外型設計,並觀察分析其實際飛行狀態,再以理論與經驗公式估算無尾翼飛行器之氣動力導數,探討其飛行穩定與操控性能。此外,並運用古典控制PID控制法則,設計控制器進行非線性受控系統之動態響應模擬。由模擬結果可看出,經由翼剖面改變與控制系統的輔助下,大幅提高了其性能,使得無尾翼飛行器克服了先天的不穩定特性,更提高了其發展空間 The tailless aircraft has a great value on the military use. Meanwhile, it is worthwhile to try and to invest in it for the investigation of MAV(Micro Air Vehicle), which is being developed now. However, because of lacking horizontal tail which is used for balance, the tailless aircraft is static unstable. Even with the attempt to enhance its characteristics of static stability, the stability of the tailless aircraft is still poor for the sake of it's low damping in aerodynamics. Therefore, it is a challenge to flight stability and control system designing. The purposes of this research are to study the stability and the control technique of the tailless aircraft. To improve its congenital lacking of stability, thought over the longitudinal static stability, dynamic stability and control system. First, find the "Reflex" airfoil is suitable for the tailless aircraft. Second, set up a non-linear and longitudinal dynamic model of the tailless aircraft. Third, design an 80cm span small airplane. Hence, observe and analyze its flying condition. Finally, utilize the theoretical and experiential equations to estimate the aerodynamic derivatives and investigate its stability and controllability. Besides, use the PID controller to proceeded the time-response simulation of the non-linear system. The result of simulation shows that the performance is improved through the change of the airfoil and with the auxiliary of the control system. With this improvement, the tailless aircraft overcome the congenital lacking of stability to broaden its utilization potential.

你喝下了多少?-台灣市售優酪乳乳酸菌生長力及抗酸性之探討

現今乳酸菌飲料風行,但是乳酸菌是否真能通過胃酸的考驗,到達腸道進行複製,利益人體?我們首先以市售乳酸菌粉(加拿大Rosell 公司,含二種菌,暫時命名為"小毛"及"小白")為預測菌種,利用分光光度計測定乳酸菌於Thioglycollate 培養基中的生長能力(OD600)。小毛在pH 值 1、 3 、5、 7 時之生長力分別為0、 0.008 、0.682 、0.847 ,小白為 0、 0.015 、0.973、 0.636。若於培養基中添加不同濃度的螺旋藻熱分解物,如加入0.01%的添加物後,小毛在以上各種pH 值生長力分別為0.042、1.291, 、1.447, 、1.213 ,小白為 0.053、1.392、 1.531、 0.988,意外發現可大幅提升菌的生長力及抗酸力。再取台灣市售4 種廠牌優酪乳(以甲、乙、丙、丁代表之),分離乳酸菌,再於各種pH 值中培養。結果在pH 3 時,螺旋藻熱分解物僅對丙廠牌有效, 乙廠牌無效, 甲與丙則有無填加生長力都很差。在pH 1 時, 則對乙、丙、丁皆有效,故建議廠商慎選菌種,並於製程及成品中添加螺旋藻熱分解物。The yogurt is a popular drink. But whether the lactobacilli inside can resist the destruction of gastric acid and grow well in the intestinal tract is still questionable. We used pure lactobacilli powder (Rosell Company, Canada, containing two bacteria named in this report as "Little Hair" and "Small White") for pre-test. The growth ability in thioglycollate medium was determined by spectrophotometer (OD600). The results of bacterial growth at pH 1, 3, 5, and 7 for "Little Hair" were 0, 0.008, 0.682, and 0.847, respectively. Those for "Small White" were 0, 0.015, 0.973, and 0.636, respectively. After supplement with 0.01% of the boiled lysate of Spirulina algae (ProBio Biotech, Taiwan), growth abilities at pH 1, 3, 5, and 7 for "Little Hair" were 0.042, 1.292, 1.447, and 1.213, respectively. Those for "Small White" were 0.053, 1.392, 1.531, and 0.988, respectively. The algae extract amply promotes the growth and acid-resistance, especially at pH 3, of these bacteria. The lactobacilli isolated from four different products of yogurt in Taiwan, named as A, B, C, and D, were then tested as above. Results showed the supplement with the boiled lysate of Spirulina algae was very effective, at pH 3, for promoting growth of C, but not effective for B. Growth abilities of both A and D were very unsatisfactory with or without this supplement. At pH 1, algae lysate supplement significantly improved the growths of B, C, and D. Therefore, this supplement in culture and product for yogurt preparation was suggested.

廢紙漿發酵產氫之探究

氫氣在燃燒後只會產生水而不產生溫室氣體之二氧化碳,可謂一種潔淨能源。 生質能源是屬於碳中性(Carbon neutral)型之利用方式,因此本研究著眼於如何建構一個操作簡便的共代謝系統,將生質料源從微生物之發酵反應中釋放氫氣出來。 實驗的主要方法是利用好氧性的Bacillus thermoamylovorans 與厭氧性的Clostridium butyricum 共培養分解廢紙漿以生產氫氣。廢紙漿是混合的基質,內富含纖維素、並含一些油墨及少許雜質。利用Bacillus thermoamylovorans 是好氧菌,同時也能將廢紙漿中的纖維素轉換成還原醣的特性,將原本有氧的環境轉換成絕對厭氧的環境,並將廢紙漿中的纖維素轉化成Clostridium butyricum 可以利用的還原醣。如此一來,原本不利於Clostridium butyricum 生長的環境,卻能透過簡單的共培養方式創造出有利於Clostridium butyricum 生長的環境並產生氫氣。除此之外,我們也對不同碳源、不同的植菌量、不同的氧氣量,比較其產氫能力差異,發現增加氧氣量可以提升最後的產氫量大約2.7 倍。 ;Our major goal is to develop a cost-effective biohydrogen production system by the co-culturing of Bacillus thermoamylovorans and Clostridium butyricum. The aerobic Bacillus thermoamylovorans will consume oxygen and converse waste paper pulp into reductant-sugar and the anaerobic Clostridium butyricum will generate hydrogen after oxygen is consumed. With the increase of aeration, the aerobic Bacillus thermoamylovorans growsappropriately leading to more biohydrogen production. However, in enhanced aeration condition, the Bacillus thermoamylovorans will consume sugars that can offer for the Clostridium butyricum. So we can conclude that the control of oxygen is the key point for the system to operate.

液晶顯示器製程及光學分析研究

了解液晶顯示器的製程及光學原理。

關於渦旋

A professor once told me that scientists have already known a lot about vortices, but less about how to tackle with them in here and there cases. As to my mind, this means knowing by halves. As a matter of fact, I gradually found that human may not know more than a dragonfly! A dragonfly flying in a figure of eight pattern does know about Vortices Recycling. The highlight of the experiment is the hovering ability upon a fixed point in the air. Who can stay longer will be the king of Vortices. Sometimes I am not so optimistic about mimicking a fly or a bat, but I am really very interesting in discovering which flying mechanism is more effective,『Fling Mechanism』 or 『In a figure of eight pattern』, if with the same weight and energy? How to implement their mechanism in our flying machine? It is always the best policy to do naturally with vortices. The conservation of vortices is found here and there. Vortex itself is energetic. To gain means to keep. The one who is able to keep vortices will be rewarded. As in life generation and the ability of hovering, the rule follows. Typhoons and tornados still threat us like the beasts. And what’s more, a jumbo-airplane was crashed as beaten by tip vortices of the former airplane. As the dragonflies, the beautiful acrobats of vortices , infuse in tip vortices. Not the strong contradistinction did we realize that it is time for vortices!研究渦旋已經四年。四年之中,涉獵了許多關於渦旋的實驗。當我越了解渦旋,就越佩服那些卓越的昆蟲朋友們,他們可說是調配利用渦旋的大師。從候鳥遷徙的V字型隊伍、海豚的渦旋氣球、到蜻蜓八字型的飛行機制,我很想知道:在一個固定的流場中,到底哪一種運動機制,能最有效率的提供上升的力量?而如何將昆蟲朋友們的高超技術,運用到人類飛行載具上?將是我有興趣的另一項課題。『關於渦旋』是一系列渦旋實驗,目的就是自基礎開始深入了解在地球這樣環境下渦旋的性質。(一)探討基礎的渦旋本質(二)產生相對運動下物體的的渦旋架構(三)物體取得升力和失去升力的要件(四)昆蟲飛行機制探密(五)未來展望與渦旋的運用經過長時間的觀察可以了解到:1、渦旋遵守動量守恆。是以渦旋出現時是成對的2、渦旋是具有能量的。在上升力取得方面,當攻角過大時,渦旋剝離,造成能量的損失;以至於飛行載具失速。而蜻蜓是保有渦旋並加以利用的高手,自然事半功倍。順勢而為,渦旋增強。

「從害羞到大方需要多少時間」(環境因子對含羞草開葉時間的影響)

含羞草會因為受到各種不同外界刺激(光照、外力等等),而造成膨壓改變。外 觀上表現出葉片閉合或有葉柄下垂的現象。其中含羞草處在黑暗的環境下一段時 間後,會做出睡眠運動。當它重新暴露於光照之中,將會需要一段時間以恢復原 先葉片張開的樣子。這個實驗是研究不同類型的環境因子(主要是光照和溼度)在打 破睡眠運動之後,對其葉片復原時間所造成的影響。我們針對上述環境因子在不 同狀況時,進行我們的實驗上百次,進一步得到了多項的數據。也在實驗中,為 了精確了解整個恢復的程序,而將恢復程序程序做成書面說明。以下是我們所紀 錄與分析完數據後的結果,以及我們在實驗期間,進行一些不同的實驗嘗試,所 發現不同於表面所見的驚人事實。 The mimosa can accept plenty of stimulation (light, force, etc), which results in the change of turgor pressure, and on outward appearance, it shows the phenomenon that the leaves become closed or that the stalks get pendent. Among the stimulation, the mimosa will undergo nyctinasty when it is left in the dark for a period of time, in order to enable it to be exposed to the light once more, which requires certain time. This experiment is based on how different kinds of elements of the environment (primarily light and hydro level) effects the rehabilitation time after the nyctinasty is broken. A large number of data are gained after experimenting on it for hundreds of times. Steps of habilitation are also made into illustration in writing, so as to understand the whole steps accurately in the experiment. Below are our records and analysis based on the data, including a few special experimental tries during our working time, in which some surprising facts that were discovered are different from what are seen on the surface.

動物血型及血清的研究

人類血清中存在天然的抗體,能認識A型紅血球的A抗原及B型紅血球的B抗原,因此寫型不合的血液混合會導致血液凝結。在我們的實驗中,我們發現一種異體的血清與血球相混合也會產生凝集反應,顯示動物的血清中也存在認識異種異體紅血球抗原的天然抗體。然而在實驗是常用的基因相異的七種不同品系小鼠及一種大鼠血清中,卻看不到存有天然抗體可認識彼此血球的抗體而產生凝集反應,顯示老鼠似乎異於人類,血清中沒有天然抗體來引發彼此的血球凝集。而且抗馬血清可與經電泳分離後的馬血清在洋菜膠上形成三個沉澱線,但不會與老鼠血清及牛血清有任何反應。雖然抗馬血清與人及兔血清有交叉反應,但仍顯示出其結合的特異性。除此之外,我們發現來自不同品系的小鼠及大鼠的白血球彼此會互相反應並聚集在一起,顯示不同品系的小鼠及大鼠白血球可認識同種異體及異種異體的白血球抗原。因此不只是血清中的抗體,白血球本身也可認識同種異體及異種異體的抗原。所以除了人類血清中天然抗體及經由免疫注射產生的抗馬血清之外,為經過免疫注射的人或老鼠身上的白血球也具有認識同種異體及異種異體抗原的能力,因此我們認為不僅是抗體,連白血球都可當作鑑別物種的診斷工具。

免疫治療的新展望:從一個疾病的動物模式,探討樹突狀細胞的培養與分析

胰島素依賴型糖尿病(insulin-dependent diabetes mellitus; IDDM)是一種胰島素無法正常分泌的自體免疫疾病;而NOD老鼠(non-obese diabetic mouse,NOD)的病徵與其非常相似。藉由觀察NOD老鼠發病前後外顯行為及疑導組織切片的差異,我們認為胰島素依賴型糖尿病的致病機轉是因為T細胞工及胰島組織中製造胰島素的β細胞,使胰島素分泌不足而引起糖尿病;而樹突狀細胞(dendritic cell,DC)是調控淋巴細胞反映的重要調節細胞,未來可望利用樹突狀細胞進行胰島素依賴型糖尿病的免疫調控治療。本實驗即是利用IL-4、GM-CSF使NOD老鼠的骨隨幹細胞分化樹突狀細胞,並藉由控制NOD老鼠的年紀與的數突狀細胞培養天數,希望取得較多的數突狀細胞,以利未來免疫治療之用。Insulin-dependent diabetes mellitus (IDDM) is a spontaneously occurring autoimmune disease in which cellular immune components mediate destruction of the insulin-producing βcells of the pancreas. It begins with an asymptomatic stage during theβcells are gradually destroyed. These patients have to depend on injecting insulin to lower their blood glucose, facing the dander of being infected. So we want to research into the cause of IDDM by model animal- NOD mouse (non-obese diabetic mouse). We observe the differences of exterior behavior and sections of pancreas organization between NOD mice and normal ones. It has been shown that the immunophological mechanism of IDDM is T cells destroy βcells of genetically predisposed individuals and result in insufficiency of insulin-producing. Dendritic cells(DC), having great Ag-presenting ability, are related to IDDM. We cultivate bone marrow stem cells of 5-week-old,8-week-old, and 21-week-old NOD mice treated with IL-4,GM-CSF and make them differentiate into dendritic cells. The result shows that using 8-week-old NOD mice to cultivate will get the largest amount of dendritic cells. We also compare the percentage of differentiated DCs for 6 days’ culture with 9 days’,and we find that 9 days’is better. Dendritic cells are the effect Antigen-presenting cells which can be used for immunotherapy of IDDM , though , its complicated mechanism still needs further researching and developing. We hope in the future IDDM patients could get rid of the suffering of injecting insulin in their whole life.