電容超音波膠體金粒子電位調控系統研發
費曼曾說:There is plenty of room at the bottom。喬治亞理工大學的Mostafa El-Sayed 教授發表的癌細胞辨識、與科學月刊報導『台大抗煞一號』引發我們對膠體金粒子的興趣。膠體的性質主要是由界達電位 (zeta potential)決定。參考台科大、成大、中山…等超音波應用研究,提出改良篩選物理法製造之膠體金粒子的儀器設計與製作。經沉降過濾可達平均粒徑 100 nm;而離心式篩選機與超音波管式篩選機可達平均粒徑30 nm。篩選後的膠體粒子以電容原理調控膠體金粒子之界達電位 (zeta potential),成功地從-30 mV 提升至-59 mV,並發展成電容超音波界達電位控制儀(Capacitor Ultrasonic Zeta Potential Controller)。以膠體金粒子與蛋白質鍵結量來測試調控界達電位的效果,發現蛋白質鍵結量之增加曲線與界達電位的增加曲線的增加趨勢相似;此功能的發現對於生物科技方面的應用應會有很大的幫助。透過界達電位控制系統,本研究達到費曼先生所期望的「在原子或分子的尺度上來加工材料和製造設備」。“There is plenty room at the bottom.” The words of Mr. Feynman are the beginning of nano technology. Mostafa El-Sayed, a professor of Georgia Institute Technology, identified cancer cells through nano gold-antibody complex. So, our study focuses on the zeta potential of colloidal gold particles. At first, the filtering method and equipments were developed. The theories were based on the ultrasonic studies of universities such as National Taiwan University of Science and Technology. Then the colloidal gold’s sizes were filtered to100 nm through settling. At last, by using Continual-Filtering Centrifuge (CoCe.) and Tube Well Mass (TW-MS), the mean particles sizes can be filtered to 30 nm. The most important results are: Zeta potential of the gold colloid was controlled with Capacitor Ultrasonic Zeta Potential Controller. The zeta potential can be raised from -30 mV up to -59 mV, which is -20 mV higher than the conventional pH-changing way. The function of zeta potential to protein binding quantity was tested. The increasing curves of zeta potential and protein binding quantity were similar. This property would be a significance of biotechnology. Thourgh Capacitor Ultrasonic Zeta Potential Control system, the zeta potential’s limitation of gold colliod, which is produced by SANSS (Submerged Arc Nanoparticles Synthesis System), can be controled in a wilder range. The study which is focused on nano-scale, like the wish of Mr. Feynman – “To manufacture material and produce equipment in atom and molecular scale”.
移動棋子問題的致勝策略
We consider a game played with chips on a strip of squares. The squares are labeled, left to right, with 1, 2, 3, . . ., and there are k chips initially placed on distinct squares. Two players take turns to move one of these chips to the next empty square to its left. In this project, we study four different games according to the following \r rules: Game A: the player who places a chip on square 1 wins;Game B: the player who places a chip on square 1 loses;Game C: the player who finishes up with chips on 12 . . . k wins;Game D: the player who finishes up with chips on 12 . . . k loses. After studying the cases k = 3, 4,5 and 6 for Game A and the relation among these four games, we are led to discover the winning strategy of each game for any positive integer k. The strategies of Games A, B and C are closely related through a forward or backward shifting in position. We also found that such strategies are similar to the type of Nim game that awards the player taking the last chip. Game D is totally different from the rest. To solve this game, we investigate the Nim game that declares the player taking the last chips loser. Amazingly, the strategies of two Nim games can be concisely linked by two equations. Through these two Nim games, we not only find the winning strategy of Game D but also the precise relation between Game D and all others.\r 去年我研究一個遊戲:有一列n個的方格中,從左至右依序編號為1,2,3,....n。在X1個、第X2個、第X3個格子中各放置一個棋子。甲乙二個人按照下列規則輪流移動棋子:\r 一、甲乙兩個人每次只能動一個棋子(三個棋子中任選一個)。遊戲開始由甲先移動動棋子。二、甲乙兩個人每次移動某一個棋子時,只能將這個棋子移至左邊最近的空格(若前面連續有P個棋時可以跳過前面的P個棋子而且只能跳一次),而且每個方格中最多只能放一個棋子。\r 研究這個遊戲問題時,我討論四種不同"輸贏結果"的規定:甲乙兩個人中,A誰先將三個棋子中任意一個棋子移到第一個方格,誰就是贏家。B誰先將三個棋子中任意一個棋子移到第一個方格,誰就是輸家。C誰先不能再移動任何棋子,誰就是輸家。D誰先不能再移動任何棋子,誰就是贏家。\r 當"輸贏結果"的規定採用ABCD時─我們稱為遊戲ABCD。今年我將把這個遊戲問題中棋子的個數由三個推廣到一般K個情形之後,再繼續研究遊戲的致勝策略,同時也將研究遊戲ABCD之間的關係。
樂器聲波之探討(The Study of A Sound Wave on Musical Instruments)
演奏樂器時,是使發聲體產生駐波而發出各式各樣悠揚的聲音及音調;樂器主要分成振動體(發聲體)及共鳴器兩部分,依發音方式分為弦樂器(使弦振動產生駐波)、管樂器(利用空氣柱振動產生駐波) 及打擊樂器(利用板、膜或磚等彈性材料的固有頻率振動產生駐波)。聲音有三要素:振幅、頻率及波型,響度取決於振幅大小、音調與頻率有關、波型則由不同的頻率及響度組成。樂音多變的主因是音色及音調。音色是發聲體的發音特性,取決於該發聲體的聲波波型。音調即聲音的高低,與發聲體的振動頻率材質息息相關,頻率愈高,其音調愈高,而樂曲中的音階高低則是由音調高低所構成。樂曲的製作及演奏必涉及到律制,從駐波的產生、律制的探討、頻率的測量和琴鍵的振動模型建立與波形的觀察,我們使用計頻器、示波器及有限元素ANSYS 軟體、數學計算Mathematica 軟體,我們設計一系列實驗,企圖對樂器聲波操作技巧有更進一步的認知。從實地走訪樂器製造廠,了解到設計與改良仍是樂器工藝家重要課題,本文的實驗方法可提供大型演奏會現場調音、樂器調音師或樂器工藝家設計製造樂器時參考用,對於發展文化產業期待提供更經濟與實用的建議。;Playing musical instrument is to make sounding part produce stationary wave so as to give off various gentle sounds and tones. According to different modes of sound producing, musical instruments which comprise vibrator (sounding part) and resonator can be divided into stringed instruments (which vibrate the strings to produce stationary wave), wind instruments (which produce stationary wave with vibration of the air column) and percussion instruments (which produce stationary wave with natural frequency of boards, films or bricks). Three Essentials of sound include amplitude, frequency and waveform, in which the amplitude decides the volume, tones are related to frequency and the waveforms are composed of different frequency and volume. Various musical sounds are mainly due to different timbres and tones. Timbres, sounding characteristics of sounding part, is decided by waveform of the sounding part. Tone means pitch of the sound and is closely related to vibrating frequency of sounding part. Higher frequency makes higher tones and pitch of a musical scale is decided by different tones. Music composing and playing is necessarily connected with music temperament including producing of stationary wave, discussion of temperament, measurement of frequency, establishment of vibrating mode of keys and observation of waveform. We adopted frequency counter, wave inspector, ANSYS software and Mathematica software and designed a series of experiment to get further knowledge of technique of handling musical instrument wave. After visiting musical instrument manufacturers, we learnt that design and improvement are still the essential subjects for instrument craftsmen. Experimental method in his article can provide reference for on-the-spot tuning of large concert, musical instrument tuner and musical instrument designing and manufacturing by craftsmen, and more economic and practical suggestion for cultural industry development.
波動奇蹟—皂膜與皂水共振模式之研究
本研究探討肥皂膜與肥皂水的共振現象。在肥皂膜共振方面,我們以實驗探討皂膜的共 振模式與頻率的關係;並配合共振理論模型求出薄膜厚度,再與體積密度-厚度測量方法比 較。而又發現皂膜在共振時,皂膜保存時間較平常久,故進行皂膜生命期與頻率、強度的關 係。在進行肥皂膜實驗時,肥皂水滴落在喇叭上,振動出奇特的形狀,進而探討皂水共振的 特性並嘗試建立其數學模式。 ;The research is about the resonance of soap film and soapsuds. For the resonante of soap film, we tried to find out the relation between the resonant pattern and frequency by experiment; according to the resonante model, we measured the thickness of soap film, which was compaired with volume-dencity method. We found that the life-time of the resonant soap film is longer than the normal one, so we proceeded to study the relation between the life-time, frequency, and power. We observed special resonant pattern while the soapsuds fell down on the speaker. So we studied the characteristics of resonant soapsuds, trying to make the mathematical pattern of resonant soapsuds.