未代表出國作品

罹患神經母細胞瘤的兒科病人，尤其是罹患stage IVs 神經母細胞瘤者，他們有些伴隨著非常嚴重的貧血，但卻檢測不出神經母細胞瘤已經侵犯骨髓；有時病情來勢洶洶，尤其是腫瘤細胞中已可偵測到N-myc 基因增幅者，診斷時腫瘤細胞可能已在腹腔四處擴散並已侵犯大部分的肝臟。但是，某些這種病患，特別是腫瘤細胞中N-myc 基因沒增幅者，即使在沒有治療的狀況下卻可能有自然恢復的現象，也就是腫瘤細胞會自動消退，但原因仍待進一步的證實與探討。可是，這些病人在其病情最嚴重的時候，骨髓內紅血球母細胞形態上的改變顯示可能與病毒感染有關。但是關於病毒來源的研究，現有的資訊仍然十分有限，其中最重要的是，病毒感染與引發其後天之免疫作用是否有關，更需要深層的研究。因此，為更進一步了解罹患神經母細胞瘤之兒科病人的病毒感染及病毒蛋白表現的作用，我們這次研究的目的在檢驗罹患神經母細胞瘤及貧血之兒科病人與微小病毒B19 (PVB19)、Epstein-Barr Virus (EBV)、腸病毒71 型(EV 71)和巨細胞病毒(CMV)的關係，以及病毒蛋白表現對這些病人的作用與臨床意義。In pediatric patients with neuroblastoma, in particular, those with stage IVs neuroblastoma, sometimes the disease was combined with severe anemia. However, no tumor involvement was detected in the bone marrow. Although some of these patients may have N-myc gene amplification, and the disease could have invaded many abdominal organs, especially liver, interestingly, the disease might regress spontaneously in some of these patients. The medical reason of the spontaneous regression, nonetheless, remains to be determined. It is worth noting that morphological changes of erythroid progenitor cells in the bone marrow have suggested virus infection in these pediatric patients. However, the available information of viral origin is limited. Furthermore, it is possible that the virus infection in these patients could be associated with the revocation of immune responses related to the spontaneous regression of the tumor. In this study we will investigate the relationship of parvovirus B19 (PVB19), Epstein-Barr virus (EBV), enterovirus 71 (EV71) and cytomegalovirus (CMV) with neuroblastoma by PCR in Taiwanese pediatric patients. Moreover, we will study the effect and the clinical significance of viral gene expression as well as N-myc gene amplification in these patients.

The special life cycle of the Nymphoides indica: The veins and petioles of the pleustonic leaves can asexually reproduce adventitious buds. Pleustonic adventitious buds will change the density of the plants and sink into water. When the root of submersible plants attaches to the bottom of the pool, they will extend stems to the water surface and resume the life cycle. Reticulate sigmons and astral sclerenchyma appears in the process of transformation. Astral sclerenchyma merely appear in the species of which its leaves float above the water surface, and Nymphoides sp. are the most obvious. The cell wall thickness of astral sclerenchyma is even. The cells are hollow and full of water, and they will utilize water to change turgor between axes and spines. This is also proved in imitating experiments. The reticulate sigmons are frequently seen among aguatic plants, and the horizontal structures prevent air space from collapsing. These two structures make the thin stems of Nymphoides indica sustain the leaves instead of being crushed by the floating water. 印度莕菜 ( Nymphoides indica )獨特的生長週期：浮水型葉的葉脈和葉柄可以無性繁殖不定芽，浮水型的不定芽會改變植株的密度而沉入水中，當沉水型植株的根系在池底固著後，便會以莖延伸出水面，再次展開浮水型葉的成長週期。轉變過程中會出現網狀的橫膈和星狀厚壁細胞。星狀厚壁細胞僅出現於葉片需由水中浮出水面生長的植物種類，而莕菜屬植物更明顯。星狀厚壁細胞其細胞壁厚度均勻，細胞中空且充滿水分，會利用水分在中軸與突起的棘間移動來改變膨壓變化，在模擬的實驗中也得到證實。網狀的橫膈在水生植物中是較常見到的構造，水平方向的支撐可以讓氣室不會塌陷，兩種構造的作用下使得印度莕菜細長的莖能夠支撐葉片，不會被流水沖斷。

At the website “MathLinks EveryOne,” we found a problem “Snakes on a chessboard,” which was raised by Prof. Richard Stanley. The following is the problem. A snake on the m n chessboard is a nonempty subset S of the squares of the board with the following property: Start at one of the squares and continue walking one step up or to the right, stopping at any time. The squares visited are the squares of the snake. Prove that the total number of ways to cover an m × n chessboard with disjoint snakes is a product of Fibonacci numbers. We call the total number of ways to cover a chessboard with disjoint snakes “the snake-covering number.” This problem hasn’t been solved since it was posted on September 18, 2004, so it aroused our interest to study it. First, we used the way in which we added each block to the chessboard, and therefore we discovered some regulations about the snake-covering number of the1 × n , 2 × n and 3 × n chessboard. Through “recursive relation” and “mathematical induction”, we proved the general term of the snake-covering number of the1 × n , 2 × n and 3 × n chessboard. In the following study, we found a key method in which we added a group of blocks to the chessboard. Finally, we proved the general term of the snake-covering number of the m × n chessboard. Also, we discovered the way to figure out the snake-covering number of the nonrectangular chessboard.在網站“ MathLinks EveryOne ”中，我們找到了一個有趣的問題“棋然上的蛇” ( Snakes on a chessboard ) ，這個問題是由教授 Richard Stanley 所提出。問題如下：在m x n棋盤形格子上，蛇由任意一格出發，但蛇的走法只能往右 → ，往上↑，或停住 ‧ 若此蛇已停住，將由另一條蛇來走，且不同蛇走過的格子不可重疊”證明：將 m × n 棋盤形格子完全覆蓋的總方法數為費氐（ Fibonacci ）數列某些項的乘積。我們將把棋盤形格子完全覆蓋的所有方法數稱之為“蛇填充數” 由於這個問題自從 2004年 9 月 18 日被登在網站上後，還沒有人提出解答，於是引發了我們研究的興趣。首先，我們使用了將一個一個格子加到棋盤上的方法，並發現了 l × n 、 2 x n、 3 × n 棋盤形格子蛇填充數的一些規律。我們使用遞迴關係及數學歸納法來證明 l x n 、 2 x n ， 3 × n 棋盤形格子蛇填充數的一般項。在接下來的研究中我們發現一個特別的方法，一次增加數個方塊 ‧ 最後我們證明了，m x n, ，棋然形格子的蛇填充數的一般項 ‧ 而且，我們也找到如何求出不規則棋盤形格子的蛇填充數。

由於奈米科技進步，奈米材料應用在產業上具有多功能的性質。本研究使用不同波美度的色料餵食家蠶，以找出最佳的彩色蠶繭色澤，並研究其如何影響家蠶所結出的蠶繭及色料附著在蠶繭上的絲。同時對色料附著的蠶繭進行水洗、光照、微結構的觀察，以試圖找出色料與波美度之最佳組合參數。由本實驗結果得知，利用奈米色料溶液60 ml，在紅色：1.048、藍：1.058、黃：1.039 的參數下，混合飼料30g，可獲得最佳的彩色蠶繭結繭成功率、均勻度較佳、耐褪色與耐洗滌等優點，並且可獲得表面結構光滑且較細的絲徑，約為19.87μm。相對的，一般色料粒徑為微米級，色彩度優於奈米色料，但表面結構較奈米色料粗糙且線徑較粗，約為21.51μm，易於褪色及不耐洗滌。 Because of the great progress of nano-technology, it has the quality of multi-functions to make use of nano-materials on industrial property. The purpose of this study is to find the best colored silkworm cocoons by mixing different consistency of pigments to feed silkworms. At the same time, this study wished to explore how the different consistency of pigments influenced the silkworm cocoons that the silkworms produced. Besides, in order to find the better association between pigments and Baume degrees, this study exposed the cocoons under different lights, washed with different detergents and take observations of micro-structure of the cocoons. The results of this study are as follows: using the nano-pigments 60 ml in different density, that is, red:1.048, blue:1.058, and yellow:1.039, then mixed them with silkworms’ forage 30g , in this way, best successful ratio to get colored cocoons, desired high visual effects in color, well distribution, long duration and strong resistance to detergents agents are obtained. In addition, we can still get glossy appearance and fine cocoons; the wire diameter is about the size of 19.87μm. On contrast, feeding with the ordinary pigments, the degree of colored silk is better than feeding with the nano-pigments, but the appearance of cocoons are rough and the wire diameter is about the size of 21.51μm.

本研究針對利吉惡地進行探討，研究此區之泥岩含水量、有機質含量、pH值、比重、可溶性陽離子含量、滲水特性和該區之植物種類，並探討坡度、水量對沖蝕率、山脊密度和溝痕形成之影響。 研究結果發現： 一、表層泥岩之含水率較高，深層泥岩最低。中層泥岩之有機質含量較高，表層與深層泥岩較低。各層泥岩pH值約8.1；無植被採樣點之 pH較高，有植被採樣點偏中性。有植被採樣點，其 Ca2+含量較高。 二、此區共發現十九種植物，其中銀合歡、相思樹屬優勢種。 三、坡度增加時，沖蝕率亦增加；水量增加時，沖蝕率、溝痕寬度也隨之增加，兩者呈高度正相關。第一區坡度較緩，山脊密度較大，第二區坡度較陡，山脊密度小，表面較平坦，溝痕較淺。Our research discusses with the contents of water in mudstone, the organic content, pH, the specific weight, the contents of dissoluble cation, dankness and the category of plants in Ligiligi Badland. Dissecting it`s slope, the abrasion of water, the density of mountain ridge and the formation of scuff mark. Outcome of our research： 1.Solum of mudstone is the dampest. Intermediate of mudstone has more organic content than others. Every bed of mudstone`s PH is 8.1. Having plants area is indifferent and having more Ca2+.2.We found nineteen categories of plants. For example Leucaena glauca and Taiwan acacia. 3.The more augmentation of gradient,the more increase of the abrasion of water and the breadth of the density and the abrasion of water too.

本研究以模擬實驗探討波浪在斜坡海灘上的行為。實驗在長1.8公尺、寬0.75公尺的透明水波槽中進行，以長0.90公尺、寬0.60公尺的木板在深水區產生單峰波向淺水區前進，同時以數位錄影機錄影後進行分析。結果發現單峰波由深水進入淺水，波速會變慢，但當波高對水深的比值增加到一定值時，波速隨水深變淺而變快，波高也變高。當比值繼續增加，波前方的水面形成垂直的水牆，接著波就碎了。如果坡度較緩，碎波點會離水岸線較遠，水牆維持的時間也較長。有趣的是，水波槽中的單峰波移動時，有蠕動現象，波寬會伸縮，波高會起伏，波速也會些微地忽快忽慢。 ;This study simulates the behavior of the wave on a sloping beach. Experiments are performed in a sloping wave tank. A paddle wave maker at the deeper end generates single crest waves. To analyze the wave height, speed and breaking point, a digital camera is used. The results show that when the wave moves toward the coast, the shallower the water is, the slower the wave moves. But when the ratio (wave-height/water-depth) exceeds a critical value, it turns out that when the water is shallower, the wave speed becomes faster and the wave height, higher. As the ratio keeps on increasing, the front part of wave becomes a vertical water-wall, and then breaks. If the slope is gentler, the breaking point will be farther from the coast and the water-wall will keep for a longer time. An interesting phenomenon is also found that a single crest wave squirms with slightly undulated changing of width, height, and speed while it propagates in the sloping wave tank.

This study analyzed how short-term solar activities interact with the earth atmosphere, by using two statistic methods: Diffusion Entropy Analysis (DEA), and Standard Deviation Analysis (SDA). Since solar activities influence the Earth atmosphere in its radiating heat and magnetic field, we use DEA and SDA to calculate the exponents, H and δ, of the scaling law in three time series: “the intensity of solar flare” (representing by SOLAR H-alpha flare index), “magnetic anomaly of magnetosphere” and “sea surface temperature anomaly”. The values of H and δ show the time memory and correlative relationship between the event and next event happening in time series. When H = δ = 0.5, events occur in random. When 0.5

如果n-1 個正四面體在n 個面的多面體棋盤中翻轉(如：正八面體、正二十面體、五邊雙菱錐及三角錐台棋盤)，則正四面體相互之間會受到很多限制。本研究為探討n-1 個正四面體在n 個面的多面體棋盤中，利用其翻轉的特性，翻轉至相鄰空格，進而完成：1. 每個正四面體的底面及側面均能「同色共面」。2. 在滿足以上的兩個條件下做「數字排序」。3. 探討每個遊戲在各階段是否有解的情形。最後，將遊戲推廣至正八面體在多面體棋盤中的翻轉。If n-1 pyramids can turn in the chessboard of n planes pyramids (ex: 8 planes pyramid, 20 planes pyramid, 5 sides bi rhombus pyramid and triangular pyramid chessboard) there are lost of restrictions between these pyramids. This research is discussing about the n-1 pyramids in the chessboard of n planes multi pyramid, which have the peculiarity of turn that can turn to nearby space. We found that: 1. Each pyramid’s button plane and aide plane can be “same plane same color”. 2. Matching about 2 conditions then can do “order by numbers”. 3. Search for answers of each levels in each game. Finally, the game will be propagated to eight planes pyramid can turn on the chessboard of multi pyramid.

茶由於其具有特殊的芳香氣味及口味，廣泛地被世人用為飲料，近年來的研究證據顯示茶具有促進身體健康和防癌功效，但茶中之成分，尤其兒茶素隨茶及茶沖泡方式而有所不同，因此對於茶中成分及沖泡方式的認知是一門重要的課題。 本實驗主要是探討茶沖泡方式及儲藏條件，對於茶液中成分變化的影響，探討的茶包含紅茶、烏龍茶、綠茶及其茶包。並使用質譜儀及高效能液相層析儀配備紫外光偵測器分析茶液中之成分，實驗結果顯示加蓋子的茶杯儲存茶時比沒蓋子的要好；成分變化速率又以未發酵的綠茶較發酵的紅茶和烏龍茶快；低溫儲存時，亦可延緩茶的成分變化，例如加蓋並存放於冰箱，茶甚至可置放至隔夜其成分均不會改變；尤其本實驗尚發現照光與否影響茶液成分變化甚鉅。;Tea is the most widely accepted and consumed beverage worldwide due to its characteristic aroma and taste. Recent studies have provided the strong scientific basis for understanding the health promoting effects and cancer preventive actions of tea. The components of tea especial the catechins are varied with the conditions of making tea. To understand and determine the chemical composition of tea is very important. Some investigations of the parameters on the storage and making of tea were carried on in this study. The kinds of tea studied were including black tea, oolong tea, green tea, and instant tea bags. A high performance liquid chromatograph combined with UV detector was used to analyze the components of tea. The results showed that the composition of tea solution is dependant of the exposure of light. The tea kept in cup with cover was better than that without cover. The ingredients in green tea were changed faster than those in fermentative black tea and oolong tea. The components of tea can be kept unchanged for a long time at low temperature. In refrigerator, the time can be extended to overnight.

The purpose of this paper is to study the roles of formic acid and formaldehyde playing in the Direct Methanol Fuel Cells(DMFCs).The assumption is now widely accepted that the Oxidation-reduction intermediate of cell like formic acid and formaldehyde will hinder the reaction of DMFCs. At first, we recorded data which measured the efficiency of DMFCs working under the different temperature of fuel, then we recorded data which measured the efficiency of DMFCs working under the different consistency. In the end, we compared the data we recorded before and chose the best reaction environment as standard environment for the future experiment. Then we discover intermediate has positive effect on DMFCs. we separately put formic acid and formaldehyde into fuel, and we discover the efficiency is better than\r before. For example, the volt stability and volt intensity of DMFCs are better. The above conclusion is mainly based on open current volt, equally volt and electric current density which is the standard of evaluation.本實驗主要探討甲酸、甲醛等雜質在直接甲醇燃料電池中扮演的角色，一般認為甲酸等是甲醇在電池中反應的中間產物，大多數人認為這些中間產物會阻礙燃料電池的反應。而我們先針對了甲醇在各種溫度下電池的效能先做出了圖表，並使用不同濃度的甲醇燃料來測量電池的效能並與之前溫度的圖表做比較，選出最合適的直接甲醇燃料電池反應環境作為添加雜質實驗的標準環境。接下來我們在研究過程中發現，其實中間產物可能對電池有正面的效果，我們發現甲酸、甲醛等對直接甲醇燃料電池的電源輸出有正面的影響，例如電壓穩定性與電壓強度的增強。在研究中，我們將甲酸等加入燃料電池的燃料(甲醇)內，模擬甲醇因不當保存而產生的雜質，針對添加物的濃度做些調整，以電池的開路電壓(OCV)、平均輸出電壓、以及單位面積的電流密度作為評比電池效能的標準，並找出甲酸等對燃料電池效能的影響，並進一步找出最適合的電池燃料配置。