全國中小學科展

Antiviral Therapy for Hepatitis C Virus (HCV): Black Mustard Seeds

Hepatitis C Virus (HCV) is an RNA virus, which is considered the main cause of progressive chronic liver disease, cirrhosis, and hepatocellular carcinoma (HCC) worldwide. The number of the patients who are infected with this sleeping virus is increasing rapidly every year, as the unsuitability of the current therapy – interferon α and ribavirin – for most of the genotypes is the main cause of these high rates. Hence, the recent researches are focusing on finding out a new immunotherapy to affect this virus. In this research work, Black Mustard (Brassica nigra) has been used as powdered spice samples to prepare aqueous extracts; One of the included phytochemicals in the black mustard; glucosinolates and their hydrolysis products, was proposed to be used for the HCV patients to prevent the virus progression. Also, the Isothiocyanates are shown with chemotherapeutic and anti-tumor properties. Moreover, some of the structure-related isothiocyanates have the ability to induce the enzyme paraoxonase-1 (PON-1) that is considered hepato-protective agent against liver impairment, inflammation, fibrosis and liver disease mediated by monocyte chemoattractant protein-1 (MCP-1), and is thought to affect the entry of the virus into the hepatocytes. The effect of the black mustard and the produced myrosinase enzyme on the HCV RNA replication is still unknown. In conclusion, the black mustard is thought to affect the progression and the fluidity of the HCV envelope resulting in impairment of viral binding and fusion.

Utilizing Computer Vision And Machine Learning Algorithms To Control Smart Systems Helping Physically Disabled People.

About 15% of the world's population lives with some form of disability, of whom 2-4% experience significant difficulties in functioning. The global disability prevalence is higher than previous WHO estimates, which date from the 1970s and suggested a figure of around 10%. This global estimate for disability is on the rise due to population ageing and the rapid spread of chronic diseases, as well as improvements in the methodologies used to measure disability. This research deals specifically with the physically disabled and often people with physical disabilities feel frustrated because they cannot do activities such as: playing sports and doing exercise. Having a physical disability also changes the way a person lives their life. They may find their life changes and activities they had previously included as part of their daily routine such as brushing their teeth, washing and doing household chores suddenly become a huge effort and many people require another person's help to carry out these activities. Also, they suffer from three basic challenges like; education, economic and, communication. Firstly, Education: The results of the investigation revealed that the physically handicapped. They face a lot of problems while studying they can't learn as the normal ones and they needs someone to help in learning. Secondly, Economic: they can't work and achieve income to help in his practical life. And finally Communication: they can't communicate with others because of his disability.

The Waves Fish Controller

Our oceans, coasts, and estuaries are home to diverse living things. These organisms take many forms, from the tiniest single-celled plankton to the largest animal on Earth, the blue whale. Understanding the life cycles, habits, habitats, and inter-relationships of marine life contributes to our understanding of the planet as a whole. Human influence and reliance on these species, as well as changing environmental conditions, will determine the future health of these marine inhabitants Humans influence the whole environment even if they don’t notice , the growth of men and our increasing reproduction over the years results to an over consumption of nutritious products , which makes us exploit the wildlife more and more and in the same time take parts of its habitats for us to life in and throwing our non-needed materials in what’s left of the world. And that’s a big problem because the Eco-System was just fine before we started over exploiting it in a greedy and unreasonable manner, and since the ecosystem’s parts are related altogether in an ongoing circle , the absence or the destruction of one part of It may lead to the unbalance and even destruction of the whole organized system. And that’s why as humans, it is our first duty to take care of nature generally and both fauna and flora specifically, not because of a moral code of some kind; but to protect Humanity from ourselves, and to preserve the human kind from destruction and extinction. And that’s the main goal of our project, that’s to help us organize our fishing exploitative activities with how much can the environment handle from it.

Detect the Defect

"When the Well is Dry, we will know the Worth of Water." Most of 埃及 and the world suffers from water and petrol shortage. With the current consumption rate, two-thirds of the world's population may face water shortages by 2025. These are water pollution, overpopulation, and agriculture, leading to wastewater from landfills and pipes that seep into the ground and may pollute the water, making it unfit for human consumption and waste more water. Besides, some accidents happen to water distribution and irrigation systems, causing a significant loss in water. According to the ministry of water resources, in 2016, the need for freshwater is 67 billion cubic meters. On the other hand, 埃及 receives only 55 billion cubic meters (2.6 billion cubic meters of them evaporate during runoff). Also, one of the wasting water methods in modern irrigation systems is water leakage from pipes as the water transmission and distribution lose about 31% of the produced water due to pipe leakage. Besides, every day more than 3.3 billion liters of treated water – 20 percent of the nation's supply and 234 million liters a day more than a decade ago – are lost through leaking pipes in England and Wales. Many reasons lead to leakage in pipes like water pressure, clogs, and corrosion. The leakage in pipes does not exist in the lines of water only. Also, the pipes in a petrol can cause dangerous accidents like the accident in the Bahira government that led to the death of 6 people and made 19 in a dangerous state. Our project designed a system that can detect fluid leakage and deal with it fast to prevent the wasting of fluid by using sensors and electronic circuits. Our system provides us with information about the fluid (like the amount of the flowing fluid and its speed). Therefore, if there is a difference in the reads, we understand that there is a leakage in this region, and the system will automatically stop the fluid flowing through the pipes. the system will locate all the leakage sites and send them to the mobile app with the amount wasted and the actions taken.

THE BLIND'S SHINE

Nowadays, all blind people are able to read any type of text thanks to The Braille system, which is a system of reading by touch. The Braille system provides a good and important help to blind people but it’s not enough. They try to integrate into society, try to read and write the same as those blessed with sight. However, only 18% of people can actually write in Braille and doing so takes a lot of effort. While Braille techniques have existed for many years now, there isn’t one that takes advantage of the comfort and easiness of modern technology. To be fair and give more chances to the blind people, and with all the available technologies nowadays, we must find solutions and innovative ideas to fulfill this objective. And this is how our project was born. To be honest, it’s not just a project, for us it’s a dream. Our focus in this project is creating an automatic machine based on transforming our language to their language and transforming this new invention to assist the blind in writing whole texts through speaking. It will be easier than the traditional way. This part of the project will help us print Braille on paper automatically in the cheapest, fastest and easiest way, unlike the traditional method that not only takes a lot of time but also needs a professional. Our printer will only cost approximately 250$ compared to regular printers that cost 6500$! the principles of the code of the speech recognition are voice pickup in all languages as first step, second speech recognition, then speech translation, after that speech analysis and finally translation into Braille and printing it. As for the future, we will work on face, object and image recognition as a scanner to make the visually impaired people read the name of the object and recognize people’s faces like anyone else.

Conscious Brain Mind-Controlled Cybonthitic Cyborg Bionic-Leg - V2

Lower limb amputations affect about 28.9 million people worldwide, influencing normal human functions, we are developing a conscious brain mind-controlled Cybonthitic cyborg bionic-leg to provide a professional solution for this problem, which is classified as restricted knee movement, short-term solution, limited pressure bearing, unspecific analog reading of EMG; Because the output voltage measured in nano-volts, resulting in unspecific knee movement. The functionality of these modern gadgets is still limited due to a lack of neuromuscular control (i.e. For movement creation, control relies on human efferent neural signals to peripheral muscles). Electromyographic (EMG) or myoelectric signals are neuromuscular control signals that can be recorded from muscles for our engineering goals. We worked on a sophisticated prosthetic knee design with a 100-degree angle of motion. We also used a specific type of coiled spring to absorb abrupt or unexpected motion force. In addition, we amplified the EMG output from (Nano-Voltage) to (Milli-Voltage) using customized instrumentation amplifiers (operational amplifiers). We used a full-wave rectifier to convert AC to DC, as a consequence of these procedures, sine-wave output voltage measures in millivolts, and the spring constant indicates the most force for every 1cm. Von mises Stress analysis shows bearing as 3000N is the maximum load for the design. Detecting the edge of a stairwell using the first derivative. The benefit of a system that controls the prosthetic limb is activated by the patient’s own EMG impulses, rather than sensors linked to the body.

Overcoming Motion Disorders

Helping in overcoming the motion disorders is an important thing which deserve striving for. Every year number of people who have MS or paresis (paraparesis) is increasing. The device has effective results for the patients and it backs to finding the conditions of natural treatments in the device. Obviously, this device helps them to keep standing and achieve the required exercises the movement like normal people by using their hands. The degree of improvement differs from person to another as depends on the hardness of the disease and injury kind.