2007年

細胞凋亡具有控制生物體細胞數目之功能，能讓特定的細胞走向死亡，因此若能掌握其作用機制，便可能藉由調控細胞凋亡的發生，進而應用於癌症治療。前人研究（2.）指出，經基因重組技術純化之口蹄疫病毒鞘蛋白rVP1，會導致BHK-21的Akt 蛋白質去活化，引起細胞凋亡的現象。然而在其後續的研究中，卻發現到在BHK-21中大量表現磷酸化的Akt 蛋白質，並無法反轉由rVP1 所誘發之細胞凋亡。因此本實驗利用二維蛋白質電泳，尋找Akt pathway 以外之細胞凋亡相關蛋白質。目前已證明Prohibitin 此一蛋白質，在由rVP1 所引起之細胞凋亡中，有自細胞核移動至細胞質的現象。此外，亦經由實驗排除Prohibitin 位於Akt pathway 的可能性。Western Blot 之結果更顯示，經rVP1 處理後，Prohibitin 在很短的時間內便出現遷移的現象，故推測其具有調控細胞凋亡上游反應的功能。Apoptosis can lead some specific cells to programmed death, thus, it is a major way for creatures to control their cells amounts. If we can command the mechanism of apoptosis, we may use it as a therapy for cancer by artificial regulation of apoptosis. VP1 is one of the capsid proteins of Foot and Mouth Disease Virus (FMDV). A research (2.) has indicated that the recombinant VP1 (rVP1) can result in dephosphorylation of Akt in BHK-21, and then lead the cells to apoptosis. However, in their follow-up experiments, they discovered that even if they expressed great amount of phospho-Akt in BHK-21, it still couldn’t reverse the apoptosis induced by rVP1. Therefore, this experiment takes the advantage of two-dimension protein electrophoresis (2D) in order to find apoptotic proteins excluded from the Akt pathway. I have found that Prohibitin exports from nucleus to cytosol after rVP1 treatment. Furthermore, I eliminate the possibility that Prohibitin’s may be located in Akt pathway. The results of Western Blot also shows that protein amount of Prohibitin in BHK-21 increase after rVP1 treatment, hence the purpose of nuclear export of Prohibitin might not be to degrade it. It might have some much more important function in the process of exportation. Besides, Prohibitin exports to cytosol in quite a short time after rVP1 treatment. According to this phenomenon, I suppose that Prohibitin has a role as a regulator of apoptotic up-stream reactions.

The objective of this project is to investigate styrene butadiene rubber(SBR), which is the most important synthetic rubber. The project contains production methods, properties, safety methods and applications for emulsion SBR. The goal is to determine which production technique of SBR is the most beneficial. This is based on the chemical and physical properties of the final product and its quality. The process that is used in the project is emulsion SBR with combined coagulation stripping. The rubber production plant is a profitable venture. The total capital cost is estimated around $31,361,572, with an annual production cost of about $67,281,378 yearly, generating revenues of $73,801,760 per fiscal year, with an interest rate of 5%. The life of the plant is 15 years and would produce 50,000 ton/year.

This study was to explore the nature of two basic constitutes of the regular pentagon,With these two constitutes, the regular pentagon could be multiplied into any times in size. We used four multiplication methodsto show how the regular pentagon enlarge and to verify that the enlarged regular pentagons derived from computer did exist. By integrating these four multiplication rules, we were able to arrange regular pentagon of any length of side, and evidenced the equation was ( If m,n is the number of A,B of a regular pentagon respectively ) When we tried to verify if any regular pentagon could be constituted by other smaller regular pentagons, we found that it was un-dividable only if the length of pentagon side were (the number of A, B were the 2n and 2n-1 item of Lucas Sequence), otherwise, any regular pentagon is able to be constituted by other smaller regular pentagons. The divided forms could be multiple. We also found that any pentagon could be divided by two successive un-dividable pentagons, which is called “standard division rule”. We expected to derive all kinds of division by analysis of two successive un-dividable pentagons in standard division rule. 這個研究起源於一個拼圖玩具：利用兩種黃金三角形排出指定大小的正五邊形。我們的研究動機是：一、 假如無限量供應A 和B，能夠拼出哪些邊長的正五邊形？二、 哪些拼好的正五邊形不能拆成一些較小的正五邊形？我們將研究的主要結果分述如下：

蓮花效應是指蓮葉表面具有奈米纖毛結構，因此只要葉面稍微傾斜，水珠就會滾離葉面，在我們生活週遭，許多植物具有蓮花效應。本實驗選擇彩葉山漆莖作為研究材料，因為我們發現在同一植株上，嫩葉的蓮花效應最佳，而老葉幾乎無蓮花效應。當彩葉山漆莖的新葉轉為老葉，蓮花效應會減弱，甚至消失。我們以不同水量、土壤酸鹼值及光照作為變因，來探討蓮花效應改變的原因，結果發現水量並非主要影響蓮花效應改變的變因；土壤過酸或過鹼，會減弱新葉及嫩葉的蓮花效應；置於暗室則使整株彩葉山漆莖所有葉面皆無蓮花效應。許多植物的性狀，在老化或面臨環境改變時，會將控制性狀的基因開啟或關閉。因此，我們推論，當環境因子改變時，植物的蓮花效應可能是經由基因層次的調控，藉以增強或減弱此性狀的表現。如果不是基因的開啟或關閉，則有可能僅是葉表面的結構發生些微的改變，真正詳細的機制仍有待進一步的確認。;We choose Breynia nivosa (Bull ex W. G. Smith) Small as a model plant to study the lotus effect on the leaves for the reason that on the same chosen plant the new-born leaves have the best lotus effect while the elder ones have little lotus effect. When the new leaves turns into elder ones, the lotus effect also turns weaker or even vanishes. To explore the exact mechanisms, we take water quantity、soil pH、and light density as the experimental factors. The results show that water quantity cannot affect the lotus effect on all leaves, change in soil pH can decrease the lotus effect on the new and new-born leaves, and dark treatments can eliminate the lotus effect on all leaves. When the environments change, the phenotypes of plants could also be changed to adapt to the new conditions by turning on or off genes. Therefore, we suggest that the lotus effect on the leaves is also controlled by genes to increase or decrease its phentype so as to adapt to the changing environments. If not, it may simply be a little change of the surface structure of the leaves. The detailed mechanism remains to be confirmed further.

黑擬蛺蝶(Junonia iphita iphita)為台灣地區常見的蛺蝶，其幼蟲具有築巢行為，但文獻中對其幼蟲行為的描述極少，因此本實驗探討黑擬蛺蝶幼蟲在野外的族群變化與環境之關係，並研究幼蟲築巢行為，以探討其適應環境的生存策略。首先於室內及恆溫生長箱中飼養幼蟲，以建立其生活史基本資料，並於野外統計各齡期幼蟲在不同植物上的數量變化及築巢行為的差異，以探討不同環境因素對幼蟲築巢之影響。由實驗結果得知，黑擬蛺蝶生活史短，可取食多種爵床科(Acanthaceae)之植物，其寄主植物除文獻所紀錄之台灣馬藍(Strobilanthes formosanus)及賽山藍(Blechum pyramudatum)等外，也取食大安水蓑衣(Hydrophila pogonocalyx)、無花水蓑衣(Hygrophila violacea)、易生木(Hemigraphis repanda)及翠蘆利(Ruellia brittoniana)等。黑擬蛺蝶幼蟲野外族群波動與溫溼度及雨量等環境因子並無直接關係。黑擬蛺蝶一年發生多世代且有世代重疊情形，世代波動與四季律動關係不明顯，顯示黑擬蛺蝶對環境的適應力大。黑擬蛺蝶幼蟲利用築巢以適應環境變化，應是其幼蟲良好的生存策略。且幼蟲在強風及光線強的環境下築巢率增加，降雨時則減少。Junonia iphita iphita belongs to Nymphalidae（Lepidoptera）. They can be found easily in the wilderness of Taiwan. Its larva shows nest-making behavior. However, there is little literature documenting the behaviors of its larva. Therefore, the purpose of this research is to investigate the relationship between the quantities of Junonia iphita iphita’s larvae and its natural habitat, to research its nesting behaviors, and to investigate its survival strategies to adapt to the environment. I started by raising larvae in a growth chamber under a controlled temperature in order to obtain its initial information regarding its life history. In the field, I documented the numbers and the changes of larvae at each stage on different host plants and recorded the differences in its nest-making behavior in order to find out which environment factors influence the nest-making of Junonia iphita iphita’s larvae. These experiments concluded that the life history of larvae is short. The immature intaking habit showed that the larva takes various plants of the Acanthaceae. In addition to the host plants mentioned in the literature, such as Strobilanthes formosanus, and Blechum pyramidatum, Junonia iphita iphita’s larvae also live by Hydrophila pogonocalyx, Hygrophila violacea, Hemigraphis repanda, and Ruelba brittoniana, which were not listed in the literature. Through experiments, I discovered that there is no direct correlation between the population fluctuations of larvae and it’s enviroment including factors such as temperature, humidity or rainfall. Junonia iphita iphita can produce multi-generations in a year accompanying generation overlapping. There is also no obvious correlation between the generation fluctuations and changing seasons, showing that larvae can easily adapt to the environment. Junonia iphita iphita’s larvae adapt themselves to the different environments by nest-making which should be a good survival strategy. Besides, the rate of nest-making increases when larvae are under strong winds and strong lights and decreases when the rain falls.

本研究比較2003~2005 年，冬季及夏季西經168 度之「海平面溫度異常」對「緯度」的分布圖，結果呈現在赤道附近的變動較小，在高緯度地區的變動較大，為更精確的描述此變動，將每日高緯度地區的變動以「標準差」及「最大振幅」數量化，發現在南、北半球不論2003、2004或2005 年，每7~12 天南、北半球的「冬夏季海平面溫度異常」的變動變大，上述變化在北半球較為明顯，在南半球較不規則。 與2005 年冬季1 月31 日~3月17 日的北半球地面天氣圖進行分析比對發現，溫度的變動和極地天氣系統的形成關係密切，推測原因和冬季時極地為永夜，地面空氣溫度受到兩個跟月球有關的熱源影響較大，其一為海流和極地間每日有接近2 次的潮汐交替運動，其二為月球反射日光後投射到極地時，極地大規模的冰對月光的反照，對極地微弱的加熱作用。 針對2005 年6 月1 日~7月22 日之地面天氣圖作分析，結果發現夏季緯度的溫度變異和高中低緯度天氣系統的改變關係密切，推測此時和月球對海水的吸引使地表(特別在海陸邊界)的溫度，週期性的重新分配，或對大氣應也會造成週期性的質量分配有關。 以農曆為主重製溫度的變動圖並進行比對發現，無論2003、2004或2005 年，在月相為朔及望時常出現低值。此分析結果顯示，接近朔望時，高緯度海平面溫度有較穩定且變動較小的情形。而從天氣圖、農曆標準差綜合，所得結論為地月運動應和地球上高緯度天氣系統存在某種相關性。 ;Our topic is about how the moon phase variation influences the high-latitude weather system. This study analyzes the sea surface temperature anomalies (SSTAs), along 168°W in winters and summers from 2003 to 2005. The results show that the SSTAs varied relatively small around the equator and relatively large in high-latitude regions. So we next analyze the high-latitude SSTAs by the standard deviations, the maximum amplitudes, and the north surface weather graphs. After analyzing, the result shows that the SSTAs rise for every 7 to 12 days. Moreover, they relate to the winter high-latitude weather system very much while relating to the summer medium-and-low latitude weather system a lot. We think it’s because in winter eternal night, the sunlight won’t shine on the arctic zone easily. Other heat sources may become important: (1) the tidal movements between the ocean and the arctic zone. (2) The heat radiation of the moonlight and the moonlight reflection by the polar ice shields. But in summer, the moonlight effect becomes extremely small. The tidal force becomes the bigger influence factor: (1) the tidal attraction may distribute the temperature of the border between seas and land periodically. (2) It may cause the periodic atmosphere mass distribution. Additionally, after repeating the same experiment according to the Chinese lunar calendar, we found near full-moon and new-moon time, the SSTAs are more stable. Probably because of without the moonlight, the movements of rip-tides occur and help stabilize the polar weather conditions. In conclusion, the relative movement of the moon to Earth is likely providing a crucial heat source which will affect the high-latitude climate, and the heat source size probably influences the weather system cycle.

The Project applicant proposes to develop fahaheel Beach by constructing a mall. This mall will be incipience and unique in Kuwait. The mall is divided to three parts; first part includes shops, Reception, Entertainment areas (cinema, beauty center, gymnasiums), Second part involved a food court for customers who want to stay for long time in the mall., Last part includes outdoor playgrounds, and out door game courts(tennis, foot ball, hand ball, basket ball), out door coffee shop. The intended goal of this project is to provide high quality, cost-effective, unique experiment of shopping and fishing services in accordance with global standards of excellence. Work. The Main task of the preliminary design phase was to balance the equation of any investment commercial project which is to provide a design that serves as an attraction spot for investors, shoppers and visitors. The design of this mall was based on the latest technology and techniques which helped in achieving the desired concept. It has been designed using the highest standards and finest finishing material whether internally or externally. The fine quality of material and high solar performance glass will help in minimizing the electrical load by decreasing the air conditioning load required. All material has been chosen to suit the image and quality to be resembled in the mall and the tower will turn out to be a master piece that has utilized newly introduced up to date building technical installation. The mall will provide a full service of shopping and entertainment facility covering over10,500sq.meter op space within this space are dedicated areas for fitness health, recreation, spa social, dining, entertainment, childcare and beach.

We study the effect of dark energy on the evolution of cosmic structure in a scenario where the dark energy is treated as free particles and thus can be localized. By theoretical derivation and numerical simulations, we found that: 1. The dark energy particles gain kinetic energy from a moving dark matter particle through gravitational interaction. Due to energy conservation, the dark matter particle will slow down with time Ek(t) = Ek0 - 9 × 10-5[|1+3w|ρDE]1.92t where Ek(t) is the kinetic energy of the dark matter particle,Ek0 is its initial kinetic energy, w is the coefficient of equation of state for dark energy, ρDE is the mean energy density of dark energy, and t is the time. 2. The formation history and structure of galaxy clusters are different in the presence of localized dark energy. The more the localized dark energy, the earlier the formation of the cluster core. In addition, the kinetic energy Ek(R) as a function of R will be different if the ρDE is different. Thus we can compare the observed Ek(R) of clusters with our results to deduce the ρDE in our universe. The results here can be applied to the observations in the near future. 我們探討宇宙結構演化受到可局部叢集之黑暗能量粒子的影響。藉由理論推導及電腦模擬，我們發現： 一、黑暗能量粒子會透過重力交互作而從運動中的黑暗物質粒子獲得力學能。因力學能守恆，黑暗物質粒子的速率會減慢，滿足 Ek(t) = Ek0 - 9 × 10-5[|1+3w|ρDE]1.92t 其中Ek(t) 為黑暗物質粒子的動能，Ek0 為其初始動能，w 為狀態方程式係數，ρDE 為黑暗能量的平均密度，t 為時間。 二、星系團的形成過程及結構，會因可局部叢集之黑暗能量的存在而改變。黑暗能量越多時，星系團的核心會越早形成。而且動能 Ek(R) 隨著至星系中心距離R 的變化，會因 ρDE 的不同而不同，因此可以將量測到的 Ek(R) 和這裡的結果比對，推導出宇宙中的 ρDE 。 這些研究成果將可直接應用在未來的觀測結果上。

本研究是藉由數學手法探討；如何由一疊36 張四種花色的撲克牌中，尋找出保證可猜中最多張花色的方法。研究過程是以在適當的猜牌時機，以鴿籠原理、邏輯推理、二進位、分析與歸納……等數學原理與方法，搭配巧妙的策略運用而達到目的。猜牌方法：先約定好猜牌規則，助手將36 張牌背圖樣相同但非對稱的撲克牌，以旋轉牌背的方向傳達訊息。在本研究中得出利用數學原理與方法可「經由巧妙的猜牌方法保證可以猜中26 張花色」，並提供後續研究者利用本研究之結果繼續深入探討與研究。 The study is mathematically based with reasonable explanations behind it. We are to correctly guess as many cards as possible from a deck of 36 cards, with random numbers and four different suits. We will apply mathematical methods, such as pigeonhole principle, logic inference, binary system, and analytical reduction, upon right timing. Using careful arrangement of the principles and reasoning, we can reach our ultimate goal. To state guessing: Conference between the guesser and the assistant about the guessing rules, the assistant will have 36 cards with the same exact pattern on the back but not symmetrical. The pattern of the cards will be different when rotated 180o. The only communication between the two is by rotating cards. In the process we will obtain mathematical theory and methods assuring 26 cards correctly guessed, and the study is for further and deeper discussion.

在2003 年台灣國際科展之作品說明書「Concatenating Squares」中【9】與2004第三屆旺宏科學獎「SA3-119 ：與特殊型質數之倒數關聯的兩平方總和的整數分解」成果報告書中【10】，就已有令人驚訝的結果。在2005 第四屆旺宏科學獎「SA4-298 ：分和累乘再現數產生的方法及其性質探討之推廣與應用」成果報告書中【11】，更是以逆向思維進行研究推廣，創造出許多新穎且引人注意的美麗數式，由原創性的觀點來進行逆向思維的研究。正由於這些再現數充滿奇巧，且與不定方程（代數）、簡單的數整除性分析（數論）以及同餘式理論都有所關聯，我們要發展前所未有的同步關聯與研究分歧， 且是最新的發現，更以豐富的想像力、創造力與推理能力提出令人耳目一新的重要結果，得到許多從未見過世面的美麗數式，回眸觀賞時內心充滿了數學之美！;Number which when chopped into two（three）parts, added / subtracted and squared（cubed） result in the same number. Consider an n -digit number k , square it and add / subtract the right n or n .1 digits. If the resultant sum is k , then k is called a Kaprekar number. The set of n -Kaprekar integers is in one-to-one correspondence with the set of unitary divisors of 10 n m1. If instead we work in binary, it turns out that every even perfect number is n - Kaprekar for some n . We wish to find a general pattern for numbers these numbers cubed or 3-D Kaprekar. We also investigate some 3-D Kaprekar of special forms. In addition, some results relating to the properties of the Kaprekar numbers also presented. This study indicates the “interesting” and “pragmatic” natures of the research project. We have developed the original results based upon his initiatives and has thus created a new horizon through the research project. This is the proudest achievement for this study. Generalization of Some Curiously Fascinating Integer Sequences：Various Recurrent Numbers！