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本研究主要是探討液晶面板在不同的電壓下,對紅外光區及可見光區之穿透光譜。藉由控制外加液晶面板兩側的電壓,改變內部的電場強度,驅使液晶分子長軸方向改變(偏轉),以達到控制穿透率之目的。施加於液晶面板兩側的電壓V大於起始電壓V0時,液晶分子長軸受電場作用與電場方向平行,減弱引導偏振光扭轉之能力,讓部分光通過偏振片。令及分別代表穿透率達到最大穿透率之10%及90%時的外加電壓,則定義「光-電開關斜率」γ為:γ =(V90-V10)/V10。透射光強度與外加電壓關係曲線則稱為「光-電開關特性曲線」。穿透率除與液晶分子之旋光程度有關,我們也做了在不同電壓下,液晶分子之穿透光譜,並討論其特性。The main idea of the project is to discuss the transmittance spectra of liquid-crystal device in the range of infrared and visual light (400~900 nm) with different electric field by changing voltage. Different biases are applied to the liquid-crystal cell, causing the axis of liquid-crystal to rotate, and the transmittances are measured. If the application of bias is greater than the threshold voltage (V0), the axis of liquid-crystal will be parallel to the electric field, and make the beam pass through polaroid. Electro-optical switching slope γ is defined as γ =(V90-V10)/V10 , where V10 and V90 are the applied voltages enabling output light signal reaches up to 10% and 90% of its maximum intensity, respectively. It is understood that transmittance depends on the optical activity of liquid-crystal cells. Besides, we will discuss the relation between wavelength and transmittance of liquid-crystal cells.
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「金」枝「玉」葉—金奈米與葉綠素的交互作用
本實驗在探討,當金奈米粒子和植物中的葉綠素產生鍵結作用力時,能量轉移的結果是否能幫助葉綠素激發電子。經由兩者混合後光譜的變化,發現兩者之間發生能量轉移。為探討此轉移現象和濃度的關係,我們將大小不同的金奈米和不同毫升數的葉綠素作用,並將其結果和金奈米與葉綠素的吸收強度和作比較,使用正規化的計算方法算出比值,由此看出兩者之間能量轉移的效率。當金顆粒約大於30nm時,正規化的數值隨的葉綠素濃度的增加而變大;而當金奈米顆粒約小於30nm時,則隨著葉綠素的增加而變小。Much attention is currently focused on chromophoric molecules because they can not only mimic natural antenna systems but also exhibit unique optical and physical properties. Chlorophyll , produced by extracting from green leaves, has electrostatic interactions with Au nanoparticles through carboxyl groups. Herein, we report the charge transfer between chlorophyll and Au nanoparticles using UV-vis electronic absorption spectroscopy. The efficiency of charge transfer from chlorophyll to Au nanoparticles was estimated by the normalization of Q-ban absorption intensity. From the observation of absorption intensity versus concentration of chlorophyll curves, we find that the efficiency of charge transfer is increased while the size of Au-particle is larger than 30nm, but decreased while the size smaller than 30nm.
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Dioscorin 對塵?造成氣管上皮細胞傷害的保護性之研究
古籍上記載山藥益肺氣,養肺陰,且最近研究報告發現山藥含有珍貴的dioscorin,其為山藥貯存養分的重要蛋白質,有抑制胰蛋白水解?之活性。而塵?糞便、屍體中的消化蛋白?會破壞呼吸道上皮細胞緊密連接處引起過敏氣喘反應。我對此甚感興趣,進而利用山藥的萃取蛋白dioscorin、塵?粗萃取蛋白及呼吸道上皮癌細胞A549,藉細胞培養、免疫螢光染色、螢光顯微攝影來實驗山藥是否真能保護上皮細胞緊密連接處。再利用膠體電泳、西方墨點法中抗體的高專一性、二抗的高靈敏度來確知我之前的實驗。另外也用ELISA 來實驗dioscorin或塵?引起A549 發炎的情況是如何。由實驗得知,dioscorin 可抑制及預防塵?引起的過敏氣喘反應;而經由ELISA 實驗發現,dioscorin 對於塵?刺激A549分泌發炎物質Eotaxin 並沒有助長或是降低的效果。It was believed that Chinese yam have benefits in treating asthma. Recently, it was found that the valuable dioscorin can be isolated from Chinese yam. The major function of dioscorin is nutrition-storage, however, it also have activities in inhibiting trypsin-like protease. This inhibitory activities trigger my interests. Because the major allergens, mites, and their stool may destroy the tight junctions of airway epithelium cells through their trypsin-protease activities. I therefore carry out an in vitro study to identify whether dioscorin can be used in protecting epithelium from the attack of mites. My results showed that dioscorin can protect the tight junctions of A549 cells from the attack of mite crude extract protein. I believed that dioscorin can be a good candidate in pharmacology application. The genetic and proteomic information are my further focus. On the other hand, we also investigated the possible activity of dioscorin in inhibiting mites-induced inflammation through using A549 as a model and employing ELISA. We found dioscorin neither inhibited nor enhanced the eotaxin being secreted from A549 under the stimulation of mites.
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Powerless Shack Cooler
Purpose of Project: To save energy and to help the underprivileged with a cooler that uses no electricity to make their lives better. Procedure/method followed: STEP 1: Collected 28, used, 2 litre plastic bottles. STEP 2: Chose the window with the best wind flow. Measured the size of the window and the room chosen. STEP 3: A sturdy thick polystyrene board was cut to the size of the window. Holes were drilled to the rim size of the bottles spacing them according to the body size of the bottles. STEP 4: Bottles were cut in half. STEP 5: The bottle necks were slid through the holes with the necks open to the inside of the room and the bodies open to the outside. STEP 6: Fixed a thermometer in the room and measured the temperature and recorded it. STEP 7: Fixed the Powerless Shack Cooler with the necks of the bottles open to the inside and the bodies open to the outside of the room. STEP 8: The temperature variation was checked and recorded every 30 minutes for 3 hours. STEP 9: Another room of the same size and window was also chosen. Fixed a thermometer and temperature variation was checked and recorded every 30 minutes for 3 hours. This served as the control of the experiment. Data/results: The room temperature decreased over time inside the room where the Powerless Shack Cooler was installed onto the window. But the control room maintained the initial room temperature although slight fluctuations in the room temperature were observed over time. Conclusion: The hypothesis was supported. As the air molecules moved through the bottles, it bounced off each other, and off the walls of the container, holding the air. A small volume of air passed at a high velocity. When the molecules moved faster the collision became more often. These collisions and the push increased air pressure. When the container’s space was getting smaller, the molecules picked up speed and the temperature went up. When the air was released out into the room, the volume suddenly expanded. The intermolecular spaces became larger; so less agitation and vibration of molecules took place. The molecules moved slowly. The room temperature reduced. Air inside the room became cooler. During the adiabatic expansion, air molecules used heat energy from the room and converted it into kinetic energy for faster movement.
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The fruiting body extracts of Antrodia cinnamomea exert significant anti-breast cancer cell activities
牛樟芝(Antrodia cinnamomea)是台灣特有的原生藥用真菌,長期被民間認為具有治療癌症、腹瀉、高血壓或保肝的效果。本研究的目的是探討牛樟芝子實體乙醇萃取物對人類乳癌細胞的抑制效用,乳癌是全世界女性最常見的癌症之一,我們透過比較不同培養時期三個月(AC-3)、六個月(AC-6)及九個月(AC-9)子實體之化學指紋圖譜,並測試它們抑乳癌細胞活性之差異。結果顯示,培養三個月的牛樟芝子實體AC-3抽出成份對乳癌細胞的生長抑制作用最佳;而利用西方墨點法探討牛樟芝對細胞週期或凋亡相關蛋白質的變化,推測AC-3可影響乳癌細胞的細胞週期調控,並誘發細胞凋亡。未來我們將進一步深入研究牛樟芝子實體AC-3之抗癌作用機制,並研究對乳癌細胞轉移作用的影響,找出牛樟芝子實體中主要的抗乳癌活性成分。
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本研究利用波以耳定律為基礎,以理論計算推導的方式,模擬水氣壓計的操作模式,並 探討其校準模式與誤差來源。 以此設計出的水氣壓計有以下兩個特色: 1. 大氣壓力的變化與水氣壓計液面的變化為線性關係。 2. 可以得到比水銀氣壓計更佳的靈敏度。 而在水氣壓計的校準上分別探討了標準校準、壓力差校準、溫度校準與重力密度校準。 利用標準校準可以得到水氣壓計液面變化與大氣壓力變化的線性關係式。而溫度校準與密度 校準在儀器操作環境為定溫下則可併入標準校準。 This study based on Boyle's law imitates the operation model of water barometer and discusses its calibration and sources of error. The designed water barometer has two features: 1. The relationship between atmospheric pressure and the height changes of the surface of the water barometer is linear. 2. More sensitive than that of a mercury barometer. We also discuss standard calibration, pressure calibration, thermo calibration and gravidensity calibration. The linearity between atmospheric pressure and the height changes of the surface of the water barometer is known by standard calibration; thermo calibration and gravidensity calibration can be merged into standard calibration under constant temperature surroundings.
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NO.60-02 2021 APR
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科學研習期刊目錄 本期專題 文化與數學數養 以數學建模在STEAM教育中創價數學文化 | 楊凱琳 從數學史談核心素養之涵育:以「畢氏定理」為例 | 蘇意雯 怎識數學真面目?談數學文化與素養 | 劉柏宏 數學建模—操作實務與建構理論的橋樑 | 蕭志如 數學素養導向評量簡介 | 吳正新 談數學素養-生活中的數學記憶 | 李宗祐 教學現場 有數學感的分數教學:半條蛋糕平分給四個人 | 李源順、林旭霓 素養導向的數學課室樣貌―以國小三年級「小數」概念啟蒙教學為例 | 溫世展 素養導向的國小數學課室樣貌―以高年級「分數除法」為例 | 陳玉珊 「數戰棋」奠基模組融入數學教學之設計 | 孫德蘭 科學新知 看見格子點-高中數學的探究與實作 | 張宮明 朝三暮四-談Haberdasher問題的摺紙解 | 李政憲 特約專欄 繪本跨領域創造力探究學習活動 | 劉淑雯、楊紹圓 「今天飛不飛?」-金門高中生活議題之探究實作課程分析 | 丁于真、李育賢、黃琴扉 森棚教官數學題-圓形軌道碰碰車 (配合3/14國際數學日Pi Day) | 游森棚 大氣河長江水 | 盧孟明 科普活動報導 臺灣科學節創意實作科學營推廣與省思 | 洪偉清 女孩們,FUN科學! | 黃真瑱、呂玉環、林琦峯、蘇萬生 科教館GO好玩 「點實成今」-中小學科展一甲子特展紀實 | 蘇珮婷 總召集人的話
最近在看「好音樂的科學」,這是一本同時從科學理性及音樂感性的角度讓我們理解聽眾跟音樂產生共鳴的機制—情感連結,當然還有很多好東西要深究此書才能享用到。科學如同音樂般,透過多層次的轉譯,透過不簡單的語言,讓受眾在情感上受到挑戰、啟發,才有機會與情感對準頻率產生共振,才有主動探究的力道。試想一條琴弦,琴弦的材料、鎖緊的張力以及固定的方式都會對於彈奏的效果有所影響;這時需要數學建模把弦的振動方程式推導出來,再來就是有系統的求解,從不同的振動模態跟音樂之間的關係開始有了連結。
數學建模需要豐富的生活經驗作為後盾,數學建模歷程對於問題解決是個很好的學習典範,又數學建模與STEAM相關學科的整合是實踐數學文化多種價值的很好策略。「文化中的數學」與「數學中的文化」交錯互動耦合成為「數學文化」,您知道多少種畢氏定理的證明方法?人類發展過程中的數學扮演的角色可以透過「柏拉圖多面體」的美與「七橋問題」的趣味來說明。結合數學史的脈絡,展現不同時空文明間的問題解決方法,可以協助學習者將抽象觀念具體化,在學習數學過程中,也能認識這些問題在我們人類文化中代表的意涵。
想知道如何建立「帶著走」的數學能力嗎?如何建立素養導向評量工具?這些目標都是讓學生從真實情境中,學習思考、提問以及建立問題解決的能力,進而產生學習遷移,達到終身學習的目標。生活中的數學記憶則透過生活中的許多實例,如鉛筆工廠的倒三角形容器、酒杯堆疊的二階等差數列、祈福摺紙、牛奶盒的堆疊,讓學生理解生活中的數學應用;有空時也該搜尋自然界中無所不在的數學元素,讓數學之美提升對數學的相關概念及精神並內化到自己的所學。
熟悉代數運算的大人們遇見算術問題的解釋,就突然間發現需要回到童年時期的思考。國小的數學教育是很具挑戰性的,如何在先備知識不多的情境之下逐步建構學生的知識體系?半條蛋糕平分給四個人,要如何表達有感的分數教學?如何透過生活情境、學習需求及操作有感的學習啟動小學三年級的小數啟蒙教學?還有高年級的分數除法,結合數感理論的讓學生說、讓學生畫圖、讓學生舉例等教學策略,引導學生有感的數學學習。
課堂上要吸引學生的目光需要好的任務設計,如何透過活動及遊戲在競爭中增加挑戰性,還要從玩樂中增強學生數學的準備度?看見格子點---高中數學的探究與實作是思考與探究的很好例子,很值得讀者拿起鉛筆,跟著做一遍,動腦歸納動手畫。切割及拼布問題--朝三暮四,是講縫紉商透過適當切割正三角形拼布,再重新拼組為正方形的問題;透過討論四種不盡相同的正方形切割重拚為正三角的組法,並比較不同切割方式的差異性,非常有趣,看了好想跟著動手裁切拼裝。
繪本跨領域創造力探究學習活動透過第一線教師的學習活動分享,讓讀者有典範學習之效。「今天飛不飛?」一文讓讀者理解使用航空站公開資訊結合生活議題,做出不同條件的估算,以達探究與實作之效。森鵬教官照例給了趣味有挑戰性的圓形軌道碰碰車,三輛車從十二等分圓周上的指定出發點及指定方向出發,在特定條件及設定的規則下,這三部車要經過多久才能同時回到原來的出發點。
地上的河流、空中水氣形成的大氣河是全球水循環的基本現象,值此久旱不雨的今天,讀此文章特別有感;對於大氣河的發生及地點的氣象預報準確度提升,有助於因應變動加劇的未來。舉辦活動是需樣樣兼顧、統籌運轉且勞心勞力的工作,臺灣科學節創意實作科學營的舉辦,綿密的合作夥伴以及各方資源的投入都值得參考學習。科教館透過執行科技部女性科技人才培育計畫,入校推廣科學實作的課程以及推動高年級女學生探究與實作課程的教學實況。中小學科展六十年了,有許多好作品值得學習,「點實成今」-中小學科展一甲子特展紀實呈現整個策展的理念以及所欲表達的探究、好奇及融入生活;展現創新思考、解決問題與合作學習的科展精神。
這一期的科學研習月刊是數學含量很高的一期,讓我們跟著動手玩玩、動腦想想,也趁機省思數學文化及數學學習的各個面向。
總召編輯委員 - 李旺龍 關於本刊
出版單位:國立臺灣科學教育館
發行人:劉火欽
總召集人:李旺龍
編輯委員: 物理科吳仲卿/陳耀榮/李柏翰/盧玉玲
| 化學科古建國/許良榮/王伯昌/林如章/周金城
| 生物科王美芬/蕭世輝/陳建志/郭淑妙
| 地球科學許民陽/王郁軒/李文禮/謝隆欽 科技科張玉山/汪殿杰/林育沖/趙珩宇
| 數學科李源順/鄧家駿/溫世展/張宮明
| 跨領域學科李名揚/連信仲
| 特約專欄 游森棚/黃琴扉/陳正改/劉淑雯
策劃:曾聰邦
主編:吳中益
本月專題特約主編:李源順
編輯:佟冠誼
網頁設計編輯:施曉恬
投稿規範請來信詢問:article@mail.ntsec.gov.tw
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抑制水果黑色素形成之新理論及研發美白保養品之新概念
PPO 是一種含銅的多酚氧化? (E. C. 1. 14. 18. 1),主要是將酚類 (phenol) 氧化成二酚類(diphenol),更近一步的變成quinones,後者是一種不溶於水的褐色聚合物,在植物中造成褐化最主要原因,然而在人類皮膚則產生黑色素 (melanin)。我們提出有一種揮發性的抑制劑存在動植物體內,此種抑制劑會抑制生物體內PPO 的活性。植物在收成後,揮發性的抑制劑逐漸消失,導致內生性的PPO 活性逐漸上升,因此植物便會產生深褐色的斑點。在本研究中,我們以玉蘭花作為例子,以生化酵素動力實驗、部分純化黑色素抑制劑來解釋揮發性抑制劑在植物體內的存在及其作用,更進一步對水果快速褐化提出一種新的理論。研究發現PPO 的褐化反應就像是人體內酪氨酸? (tyrosinase) 的催化反應,酪氨酸?可以使人體產生黑色素而累積在皮膚上形成黑斑,利用〝人工皮膚〞模擬揮發性黑色素抑制物的作用,證明,防止PPO 抑制劑之揮發可能在未來美白保養品工業裡扮演一極具潛力的角色。Polyphenol oxidase (PPO) or tyrosinase (E.C. 1.14.18.1) is an important and ubiquitous enzyme responsible for browning in plants and melanization in animals. PPO is a copper-containing enzyme that catalyzes the chain-oxidation from monophenol or polyphenols to o-diphenols and subsequent o-quinones. The resulting quinones are large wate-insoluble polymers with dark brown color. We proposed that volatile inhibitors are associated with the plant PPO and block the PPO activity in vivo. While post-harvesting the volatile inhibitors evaporate, the endogenous PPO is then activated and therefore instantly produces dark quinone pigment. In the present study using magnolia flowers as an example, we show the presence of a potent volatile inhibitor(s) for PPO in plant. The novel finding clarifies the mechanism involved in the browning phenomenon of post-harvesting for most fruits. Since the PPO is also know present in human as tyrosinase responsible for the formation of “darkening spots” on skin, the finding of evaporation of potent PPO inhibitor may be potentially used as a strategy in developing a novel cosmetic product.
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引擎排氣噪音反饋至道路交通流量與車輛排放控制
運用自製低頻噪音( The relations between vehicle average speed with low frequency engine exhaust noise(
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我們藉由電腦模擬來研究宇宙微波背景輻射中之Sunyaev-Zel’dovich 效應,以探討星系團及宇宙的一些根本性質。重要的發現有:
以上的結果,將可在短期的未來直接應用在許多期待中的觀測結果上,以揭開星團的總質量、質量密度、以及宇宙中的黑暗能量等神祕面紗。
We study the important properties of the galaxy clusters and our universe by using numerical simulations for the Sunyaev-Zel’dovich effect in the Cosmic Microwave Background. We found that:
These results can be applied to the observations in the near future, in order to reveal the total mass of clusters, their mass density profile, and the dark energy of our universe.
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Digital Viedo Compression Enhancement With Reduced Psychovisual Redundancy
Video compression is indispensable to web streaming and memory storage.Most video\r compression technology has difficulty to achieve high quality video at lower bit\r rates.Apparently,limited transmission bandwidth and network resources often degrade\r video signals.Thus the goal of my research was to enhance video degrade video\r signals.Thus the goal of my research was to enhance video compression performance and\r to improve visual quality.It is hypothesized that the reduction in neighboring pixels\r coding,and humans perceptual mechanisms(psychovisual)redundancy could produce a\r low-complexity geometry streams for animated visual objects.A set of algorithms is\r developed to parse bidirectional interpolation pixels into their characteristic cells,which\r vary in spectral energy and wavelength.The bits contained in these cells are vectorized and\r transformed recursively to identify lower correlations among vector arrarys for blocks\r filtering.DCT function calculates energy ratios between high spatial frequency and low\r spatial frequency,to devote most of the highest spatial frequency bits with the calculated\r energy ratios.A variable quantization method is used to measure the sensitivity of colors\r and its intensity ratios to restore any missing high spatial frequency pixels.presnted in\r mathematical intrinsic.This approach leads to the ability to compress video data that\r normally require a large amount of memory to store and high bandwidth to\r transmit,Results form the enhanced video compression experiment have attained\r 0.1bpp(256kbps,25fps)without noticeable effects comparable to the video compression\r technique that achieved 0.5bpp(1.5Mbps,25fps)in use today.
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美麗的陷阱 - 探討線蟲捕捉菌之捕蟲機制及應用
線蟲為植物發生病蟲害感染的病源之一,而台灣的松樹,目前正面臨著松材線蟲入侵的危機。從文獻的探討中,發現線蟲有其自然界的天敵 - 線蟲捕捉菌。本實驗著重在探討線蟲捕捉菌特殊的捕捉機制。當線蟲捕捉菌附近出現線蟲時,會展生誘引線蟲的物質,並設計了一步步的實驗,去探討此誘引物質的捕蟲效能及其成分。現在,已經發現此誘引物質為一揮發性氣體。往後將會設法增加其誘引氣體的產量,並使用氣相層析儀分析之。最後希望可以將此物質應用到微生物防治上,期望能解決台灣松樹被線蟲感染的問題。 In Taiwan, all of the pine trees have one common problem - nematodes, which causes diseases in plants. And this experiment focuses on the nematodes’ natural enemy - nematophagous fungi and its “peculiarly caused mechanism.” When nematodes appear near nematophagous fungi, the latter will produce some substance to tempt the former. To investigate this alluring substance, a series of experiments are done and systematic steps are taken. The first finding is that this substance is a volatility gas. Later in this research, measures will be taken to make “rematophagous fungi” produce more of this gas. And “gas chromatograph” will be used to analyze this gas in the future. Finally, the possibility of applying this substance to the defensive measure of microbiology will be discussed.
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