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Synthesis and Analysis of New BiS2-based Layered Superconductor
本研究主要探討傾角對面轉變的影響與面轉變的原因。當柱體由肥皂水中拉起時,泡膜圖形可分為中央膜平行與垂直底面的形式,兩種形式因高的變化而互相轉換的過程稱為面轉變。三到六角柱傾角越大,面轉變時的高越大,反之亦然;六角柱可以面轉變,且在40°到45°之間有臨界角度存在。本研究以力與能量的角度解釋面轉變.泡膜藉由改變面積以達到最低的能量、維持穩定狀態,因此本研究計算、比較不同形式的泡膜面積,以解釋面轉變。我們同時發現三角錐與四角錐都不會發生面轉換;三角錐的實驗值多大於理論值,四角錐的實驗值則多小於理論值。
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Understanding the Modern Diagnoses of Protein C Deficiency "Pcd" with Unknown Gene Plays a Critical Role in the Inherited Thrombophilia
Protein C deficiency (PCD) is found in 1 out of 200 to 500 persons in the general global population which is also one of the common conditions of Inherited thrombophilia, it’s characterized by an increased tendency of blood to clot in human blood vessels. It is caused by several factors including mutations in the genes involved in thrombin binding, protein c activation and numerous clotting factors. This includes F5 (Factor 5 Leiden) gene on chromosome 1q24.2, F7 (Prothrombin) gene on chromosome 13q34, SERPINC1 (serpin peptidase inhibitor C) on chromosome 1q25.2, SERPIND1 (serpin peptidase inhibitor D) on chromosome 22q11.21, HRG (Histidine Rich Glycoprotein) on chromosome 3q27.3, PLAT (Plasminogen Activator) on chromosome 8q11.21 and THBD (Thrombomodulin) gene on chromosome 20p11.21. In the current study, a three Saudi families with inherited thrombophilia has been recruited to identify the underlying cause of this special condition. Whole exome sequencing, targeting all coding exons of the human genome, was performed using Illumina Nextera library preparation kits followed by paired-end sequencing on Illumina NextSeq500 instrument. Reads quality control was performed and reads were aligned to the reference genome using BWA software. Variants calling and annotation was performed using GATK. All known genes involved in causing inherited thrombophilia All known genes involved in causing PCD were excluded by whole exome sequencing. The genes that were previously reported to be involved in inherited thrombophilia were checked for any causative variant. No mutation has been identified in known genes. identifying a novel gene underlying PCD. The Result of this study will hopefully pave the way to better understanding the disease pathophysiology and help in developing DNA based diagnosis, carrier screening and somatic gene therapy.
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以奈米銦顆粒或鈉離子修飾竹子導電作為新型熱電材料之研究
熱電材料的條件為導熱差,電導率高的材料,此特性可將熱能轉換成電能,為一新興的再生能源。竹子生長快,為一導熱差的材質,但電導率低。本實驗將野生孟宗竹加工裁切,浸泡於飽和食鹽水加上奈米銦顆粒(73mg/ml)環境中,以高壓蒸氣(121℃、1.1 atm/cm2)處理40分鐘後測量處理前後其電阻變化、增加兩端溫度差及電壓改變的電流密度、增加溫度改變的電流,及熱導率等,並以複式顯微鏡觀察,確認奈米銦顆粒的確有進入竹子維管束內。實驗結果顯示,以飽和食鹽水及奈米銦顆粒高壓蒸氣法處理的竹片,相對於對照組,電導率上升了約1706倍,但熱擴散度只上升了約10%,熱電優值(Thermoelectric Figure of Merit) ZT為 0.059。本實驗方法有效提升竹子的電導率,證實竹子是一個有潛力的新興熱電材料。
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The purpose of my project was to prove if the seeds of invasive plants are spread throughout the Peace region in hay harvested by local farmers. Invasive plants are so dangerous because they adapt to their environment fast and some of them can cause harm to both animals and humans. Within a year they can completely wipe the ecosystem out of native plants. Many invasive plants are either poisonous or can affect the systems of the animals body’s. I collected 22 hay samples from local farms around the North Peace region. I conducted a survey to help collect information about the samples. A pretest was conducted to determine which of two homemade sifters (one with three layers of decreasing size wire mesh, and one with 6 layers of materials with larger size holes) was the best for sifting through hay. I was able to determine that the larger sifter was easier for sifting hay. I sifted through all 22 samples with the larger sifter. I individually looked through each layer and removed what I believed to be seeds. Each seed was individually bagged, labeled, and photographed through a microscope. After each seed was photographed they were planted to help identify the seeds. I contacted a seed specialist. I was able to send him the images of my seeds. He helped me to identify my findings. I removed a total of 5568 potential seeds in my 22 samples. Out of all the potential seeds found 628 seeds were invasive. All invasive plants identified either cause pain to animals or they easily over take the native plants.
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The Locus of Mid-Tangent Points of Planar Curves
In this project, we defined a mid-tangent point with respect to a fixed point X and a tangent at a point Y on a planar curve C as a point on the tangent that is equidistant from X and Y. We studied the locus of mid-tangent points of conic sections. We found that the locus of mid-tangent points of most conic sections are non-linear curves. However, we observed and proved by using Euclidean geometry that the locus of mid-tangent points of circles are straight lines. The mapping defined by mid-tangent points was studied further. The similarity between a mid-tangent mapping and a stereographic projection was displayed as a one – to – one correspondence function. We also extended the concept of mid-tangent points to three dimensional space and found that the similarity with the stereographic projection was retained in higher dimensions. Finally, we studied the locus of mid-tangent points of a sphere to create a mapping of the sphere to a plane.
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Development of new manufacturing method to generate hydrogen energy by using waste silicon ~ Reuse of waste of the semiconductor industry for hydrogen community ~
Because of the presence of an activated multiple carbon-carbon bond, α,β-unsaturated sulfones are high-reactive compounds which are widely used in organic synthesis. These compounds readily undergo the reactions of nucleophilic addition and pericyclic processes. At the current moment, a wide range of 1,3-dipolar cycloaddition reactions with α,β-unsaturated sulfones as dipolarophilic systems is known. However the interaction of α,β-unsaturated sulfones with azinium ylides is less studied and limited to only a few examples. In the present study, the interaction between a number of stable isoquinolinium and pyridinium ylides with aliphatic and aromatic vinylsulfones has been investigated. We considered the regioselectivity of these reactions. Mostly cycloadditions of isoquinolinium ylides to α,β-unsaturated sulfones led to the mixtures of isomeric sulfonyltetrahydroindolizines in different ratios. Also we found several examples of high-regioselective addition. The stereochemical result of the cycloaddition was examined by methods of 2D correlational 1H-NOESY NMR spectroscopy and X-ray crystallographic analysis. The process of formation of major regioisomer of cycloaddition N-phenacylisoqunolinium ylide to ethylvinylsulfone was highly stereoselective. The series of new sulfonyltetrahydroindolizines with potential bioactivity were obtained. The structure of all products was proved by IR and 1H NMR
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SeedBot: Low-Cost Seeding Robot for Agricultural Applications
This paper presents a semi-autonomous seeding robot which is based on both electrical and mechanical platforms that perform advance agriculture process. SeedBot composed of four components: drilling mechanism, body of robot, seed container and paving mechanism. Other than those components the sensor system and the control system are also discussed. The aim of this study is designing and building a low-cost robotic system to automate and optimize process during farming especially for personal usage. This study demonstrates that semi-autonomous farming has crucial advantages over conventional farming. In addition to that, SeedBot provides safer, requires less manpower and precise farming than usual methods that we have so far.
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How to spill your coffee
We all do it – walk along with a cup in hand, and carelessly spill it. While it’s usually more annoying than anything else, it happens to affect almost all of us, and little is done to minimise the likelihood of it occurring. So my aim was to explain the physics behind why we spill drinks when we walk, and to investigate how we can minimise the likelihood of this occurring. I broke this investigation into two distinct parts, explaining the system of the cup, and explaining the effect of walking. From initial observations, it was clear that the cup was a resonating system. Like any resonating system, the cup has a natural frequency. When the cup is oscillated – moved back and forth – at near this frequency, the size of the liquid oscillations is very large. This is because the acceleration is in phase with the motion of the liquid, so in each cycle maximum energy is input into the system. In my investigation I experimentally measured this natural frequency, and created a mathematical model to explain this frequency. It was also found that as the size of liquid oscillations in the cup increases, so does distortion of the fluid surface, possibly enabling spilling. To systematically analyse the effect of walking, I had subjects walk on a treadmill, so walking surface and speed were controlled. However, I also needed an accurate way of measuring the motion of a carried cup. Firstly, I tried to use video analysis; however I found this far too imprecise for measuring small changes in velocity of a cup. In the end I used a smartphone to record the acceleration of a carried cup, as acceleration is what causes the movement of liquid in a cup. This allowed surprisingly accurate measurements to be made, and allowed both the size and frequency of the acceleration to be recorded. In order to relate the system of the cup and the oscillation provided whilst walking I conducted a qualitative experiment into the effect of stride frequency on the likelihood of spilling. When stride frequency was very close to the natural frequency of the cup, spilling occurred almost instantly, while it did not occur if stride frequency was much higher or lower. In the end, my research showed that to minimise the likelihood of spilling your drink walk slowly, use a narrow cup, focus on walking smoothly, and fill the cup well below the rim. Despite this, some people happen to be much smoother cup carriers than others, likely due to their individual biomechanics. And, if you really don’t want to spill your drink, you can always use a lid.
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A Backpropagation Neural Network Model on Precipitation Forecasting in the Philippines
Backpropagation neural networks were used to forecast daily rainfall with minimal error for Metro Manila in order to have an inexpensive way of accurately predicting weather. Calamities brought on by heavy rainfall have caused great economic, infrastructure and human loses. Neural networks have the ability to discern complex patterns in noisy data; this makes it a viable method for weather forecasting. Daily precipitation, humidity, rain indication, sea level pressure, temperature and maximum sustained wind speed for January 2000 to December 2010 were acquired from the Philippine Atmospheric Geophysical and Astrological Services Administration. The neural network made use of Python 2.7.2 and the backpropagation program by Neil Schemenauer (python.org). It considered different neural network architectures with a total of 2844 data sets for training and 708 data sets for testing. Each neural network’s accuracy was measured with a graph of the actual and predicted values, correlation coefficient, and root mean square error. It was observed that the neural network with architecture 5-8-1 yielded the most accurate results as it had the highest correlation coefficient of 0.48599 and smallest root mean square error of 14.84. It was also observed that the trends of the predicted values followed that of the target values. This suggests that it is possible to create a neural network with a moderate correlation given daily weather data. It is recommended that further researches make use of hourly data instead of daily data for more accurate results. Other variables, which might affect rainfall, not in this study should also be considered. This research could aid in the anticipation of calamities and the decision making involved in shipping, fishing and aviation industries.
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從三個交於一點的圓形想起──Miquel’s Theorem之推廣
根據密克定理的陳述,於一個三角形的三邊上各任取一點,則三個外接圓會交於一點,且逆定理也存在。我在確認完定理和逆定理的正確性之後,以原本定理的敘述為基礎,推廣並探討了根據該定理所能做出的相似形和圓心的軌跡,並將軌跡視為三角形的基本性質,棄續探討軌跡的交點的軌跡,最後再將密克定理和密克逆定理推廣到多邊形。
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Investigating the Effect of Coloured Light on the Behaviour and Learning of Lymnae stagnalis
Lymnae stagnalis (pond snail) is emerging as a preferable invertebrate model in understanding neurological mechanisms because of its simple nervous system. A three-cell network mediates behaviours such as aerial respiration and research has shown that small, subtle changes occurring across the network might result in a disruption of natural behaviour (Lukowiak et al. 1995). It is also known that Lymnae features a more developed eye than other molluscs and studies have shown that various wavelengths of light can activate photoreceptors producing distinct electrophysiological responses (Sakakibara et al. 2004). However, no studies have looked beyond the electrophysiological response. The purpose of this project was to determine if coloured light would firstly, elicit a behavioural response as observed in its movement and secondly, affect learning and memory through the operant conditioning of its aerial respiration.
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Studies of Hydrogen Evolution Reactions from Aluminum Foil using Waste Materials and Their Reaction Mechanism
Nowadays, the most of waste materials are incinerated and generated the toxic gases in 日本. On the other hand, the Hydrogen gas (H2) has attracted attention as clean energy due to no emissions of toxic gases. In this work, we investigated that the new hydrogen evolution system using waste materials, such as aluminum (Al) foil and lime desiccant, and also investigated their reaction mechanism. The grinded desiccant was added to Erlenmeyer flask containing 300 mL of water. After dissolution the desiccant, the Al foil was added to the solution to begin the reaction. Generated gas was determined by water displacement method. The gas components are identified by gas chromatography. We found that the waste material reaction combined with waste lime desiccant and Al foil could be used for one of the hydrogen evolution system. This reaction is depended on solubility of lime desiccant, thus mean solubility of CaO in water. The Al foil is reacted with the desiccant more than 20 times of reaction stoichiometry. The calcium ion or calcium complex ions are involved with the excess reaction of Al foil.
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