A variant of the coronavirus (2019-nCoV or COVID-19) was reported in Wuhan, China on December 31, 2019, spreading rapidly around the world. Owing to a plan to reactivate the economy, the Mexican government, requested to implement protective measures to enter establishments with confined spaces: wear a mask, provide alcohol-based hand rub and the measurement of body temperature, allowing problem when not have a fever; however, these measures cause long waiting lines, causing contagion risk. To support this problem, applied and experimental research was used, generating as a result, the creation of a robot that moves autonomously thanks to a line follower sensor. Dispenses alcohol-based hand rub and determines the temperature by means of an infrared sensor, checking that the distance is adequate, with an ultrasonic sensor, using a buzzer that emits a sound of half a second when it performs a normal detection, but, if it is equal to or greater os 38 ° C, emits a sound for 10 seconds asking the person to leave the line and go to a medical service, helping to reduce problems infections in lines

To investigate the reproduction success and natural recruitment of several Cyprinidae fish and Claridae fish species in the Allemanskraal Dam. The purpose of the project included investigating whether each individual fish species studied has a successful 2020/2021 spawning season in comparison with each other. Sections of the seine net were measured along with a distance of 10 along the shoreline. The ends of the seine nets were attached to one foot and the top of the net was held by hand. Both volunteers moved in unison while covering the 10m. The volunteer in the “deep end” moved towards the shoreline creating a semi-circle while the other volunteer remained stationary. The two ends of the net were then pulled onto the shore and the fish were collected. The results found that the Labeo Umbratus and Cyprinus carpio had the most successful spawning seasons with the highest recorded numbers. These high numbers of the Labeo Umbratus can be due to the fact that the species lays a large number of eggs. The high numbers of the Cyprinus carpio is due to the lower numbers of the other fish species as previous studies have shown that the species negatively impacts the environment which could in turn negatively impact the other fish species. The Claridae gariepinus and Labeobarbus aeneusas were the lowest. The low numbers of the Labeobarbus aneusas may be due to their slow growth and late maturity rate. The Labeo capensis had an average number relative to the other species and this is due to the fact that during the sampling period the dam was at 100% capacity as this is essential for the survival of the juvenile fish. The hypothesis was accepted as the Labeo Umbratus, Cyprinus carpio and Labeo capensis all have a successful spawning season. However, due to the size of the Cyprinus carpio, they would be most suited for a small scale fishery.

The aim of this research was to investigate whether the ecology and biology of the Orange River mudfish Labeo capensis were suitable for the species to be used in fisheries. Three fleets of the gill nets were set, parallel to the shore. One fleet was lifted, and the fish were collected by hand. The two remaining fleets were lifted the next day. The seine net was pulled for 10 metres within the littoral zone. The net was then pulled towards the shore of the dam and the procedure was repeated four times. The four fyke nets were set parallel to the shore and were left for two nettings nights and then lifted. All fish caught were collected by hand and placed into buckets. The majority (82.93%) of the fish caught were within the 0-100 mm size class. The 101-200mm and 201-300mm size classes contain similar numbers of fish, while no fish were caught in the 301-400mm size class. The hypothesis was accepted. Allemanskraal Dam, as of the study period, has a very small juvenile fish population of L. capensis, as only 7 out of 41 fish individuals caught were within the 101- 300mm fork length size class. These results show that the population of L. capensis is not established as of yet, as the research did was right after their breeding season. Historical research has shown that sexually mature individuals of the L. capensis species tend to be a minimum of 300mm SL, 4-6 years after hatching. The population was largely young-of-the-year and may develop into an established population in 3-4 years (after sexual maturity). The L. capensis population in Allemanskraal Dam has the potential to be a fishery species if suitable conditions are maintained. Establishing this species’ potential will therefore allow economically viable fisheries to utilise them sustainably and to their full economic potential.

Face pose estimation has many possible applications, ranging from driver attention measurement systems to applications in the metaverse, which this project will be focused on. Rather than using a more traditional landmark-to-pose method where the head pose is estimated via keypoints, our method trains a simple convolutional neural network, using the dataset 300W_LP, where the images are simply inputted into the network. The model is fitted with three fully connected layers that are linked to the each of the three Euler angles (yaw, pitch, and roll), alongside multiple loss functions, which improve the robustness of the network.

This is a first approach in the development of beekeeping and the preserving of bees, a crucial and important species in the balance of ecology on our planet. This project consists in designing and building a small affordable device that will help beekeepers keep an eye on their hives and prevent theft whenever and wherever they are by providing them with instant and continuous data and information about their beehive status through a mobile application. This IOT approach will rely on many physical variables especially the sound frequency of the bee buzz, which appears to be a way for the bees to communicate with each other in special circumstances. That is why; we aimed to analyze the sound frequencies of the bee buzz to detect beehive behavioral changes. Many other factors are also important for the keeping of a healthy beehive such us temperature, humidity, weight and fly activity. And as for security measures we are going to add a GPS tracker to the system to keep track of the hives and alert the beekeeper if there is any kind of danger. The development of this real time beehive monitoring system will not only help the beekeeper keep track of his hive and collect useful data but also increase the honey production and avoid many colony losses and thus preserve the bees and ensure their well-being.

Aspirin is one of the most used and well-known medicines world-wide. It can be synthesized by reacting acetic anhydride and salicylic acid in a warm temperature of around 60-80°C. This reaction is usually catalyzed by sulfuric or phosphoric acid. This paper will investigate alternative catalysts, safer and more environmentally friendly, as well as compare different synthesis methods with different heat mediums, one using a water bath and the other amicrowave. By doing so, the effects of the catalyst and the method of synthesis on the yield, purity and environmental consequence of crude aspirin synthesis will be deduced. The targeted utcome is to find the alternative method as more energy efficient, and to find a greener safer catalyst to sulfuric and phosphoric acid. Further background information, exploration, and explanation is in the appendix. The targeted outcome will be to find a viable alternative catalyst that is safer and more environmentally friendly, and to find that the microwave synthesis method consumes less energy.

Improved methods of processing latex into rubber sheets will improve the incomes of small rubber producers. There are two ways in which latex can be processed into rubber sheets: fumigation and solar incubation. The fumigation method is expensive and produces pollution, but solar incubation can cause dark, sticky rubber sheets due to UV radiation, which reduces their value. A low-cost and environmentally-friendly solution to this problem was investigated here. A UV-protective roofing panel made using Nitrogen-doped Graphene Quantum Dots (NGQDs) was developed and tested. N-GQDs were made using the hydrothermal process for 2 and 4 hours (T2 and T4) and the solvothermal process for 4, 6, and 8 hours (TS4, TS6, and TS8). It was found that all types of N-GQDs absorbed light in the UV range, withT4 showing the greatest absorption. T4 had the greatest Fluorescent Intensity (FL) value, emitting blue light, while for the solvothermal method TS6 had the highest FL value, emitting red light. T4 and TS6 were chosen for further testing, and were applied to a clear roofing tile. After installing the roof on the chamber, the temperature inside was higher than outside. Then we measure the UV protection efficiency of the roof which was 93.27%. The average temperature was 45℃, which is the temperature for drying rubber sheets. Due to the roof’s capability to absorb UV radiation and heat the chamber, our N-GQDs roof has a great ability to produce higher-quality rubber sheets.

閱讀、記憶與理解，對莘莘學子們乃至大眾來說，都是每天經歷著的重要日常。有鑑於此，本研究驗證了一款宣稱能藉由理想的閱讀難度來啟動深度認知歷程，進而提升記憶與理解的字體：Sans Forgetica的效果，以及其設計在中文的應用可能，結果發現無論在英文或中文材料中，Sans Forgetica字體都展現出提升記憶和理解的效果。另外，本研究又根據認知心理學的完形理論，提出Sans Forgetica字體效果成因的可能解釋，並以眼動追蹤技術驗證，結果雖不夠強烈，但仍具參考價值，開啟後續研究的方向。

The main goal of this paper was a creation of musical score for the composition from the 18th century Domine ad Ad juvandum in A minor and C major composed by Šimon Brixi. Another goal was finding as much information as possible related to this composition and summarize everything possible that was written previously. Separate parts were transcribed into one partiture. Nevertheless there were difficulties like mistakes in sheet music (corrected according to harmony of other voices), missing beats (replaced by identical parts of score), differences in period station. Hard times also bring on differences of period notation. The resulting musical scores can be directly used for music production, which is schemed for the next year. The second part was researching new or never-published information related to these compositions. Here I describe Š. Brixi´s life. I managed to read out the cause of Šimon Brixi death in a chronicle, which was not in the publication I found. Brixi died of tuberculosis like his son. Transcriptors, J.V.Flaška and J.J.Hoffman, are also mentioned. Lastly the information about sheet music itself and its historical context were described. Another discovery was an identification of watermark on sheet music paper. Assuming the sheet music is truly transcribed in 1742 the Kolinec paper mill watermark on the sheet music paper is the oldest evidence of its use. In this paper I summarized the historical context of the baroque era including social life, art and culture.I mentioned the most important events that were crucial for historical development in Bohemia and especially in the Klatovy region. This context can be useful for today’s musicians who want to understand the historical background and express the composition with full respect to the time of its creation.

Currently, no method can completely eliminate the human immunodeficiency virus (HIV) in an infected person. HIV employs an accessory protein called Nef that forms a complex with cellular AP-1, preventing detection of HIV-infected cells. Lovastatin has been recently identified to inhibit the formation of said Nef-AP-1 complex, but its effective concentration is remarked to be far higher than other Nef inhibitors. This study aims to develop a modified lovastatin molecule exhibiting higher binding affinity to the HIV-1 Nef protein than lovastatin in silico. Modified lovastatin molecules based on the interaction map of lovastatin with Nef were modeled, and flexible ligand-flexible receptor docking to the Nef binding site was performed using AutoDock Vina. Residues within the Nef binding site identified by Liu et al. (2019) to be crucial (Glu-63, Val-66, Phe-68, Asp-108, Leu-112, Tyr-115) were set as flexible. Fragment-based drug design was utilized to append molecular fragments to lovastatin in order to maximize its interactions with said crucial residues. From the fragment-based approach, molecule F4 ((1S,3S)‐8‐{2‐[(2R,4R)‐4‐chloro‐6‐oxooxan‐2‐yl]ethyl}‐3‐(hydroxymethyl)‐7‐methyl‐1,2,3,4‐tetrahydronaphthalen‐1‐yl 4‐aminobenzoate) exhibited a binding affinity of -9.0 kcal/mole, and its estimated IC50 ranges between 0.25-0.51 μM which is at least 7.5 times lower than the reported IC50 of lovastatin from literature. This study presents insights on the key modifications to improve lovastatin as an HIV-1 Nef inhibitor and pertinent information about the Nef binding site for future drug development studies.

As the world has become concerned about the global waste crisis and global warming, there has been a surge of research within materials science to find materials that would replace plastic, such as bioplastics or biodegradable materials, in order to reduce environmental pollution. Plastics generates the microplastics that allowed them to become cross contamination enter the ocean through land, sea and river. Science research found (Lusher et al. (2017)) over 220 species of marine animals ingested microplastic, half of them are considered relevant for commercial purpose and increasing the risk of human consumption as it can induce immune response, oxidative stress, cytotoxicity, alter membrane integrity and cause differential expression of genes. Thailand is also experiencing such a challenge, as seen by the overabundance of plastic waste that might take centuries to decompose. For example, around 1680 million personal hygiene products such as diapers, sanitary napkins, and tampons are used each year. This study highlights the use of naturally accessible absorbent fibers from malva nut (Scaphium scaphigerum) (G. Don) Guib & Planch.), which is widely available and biodegradable in nature and has a low carbon footprint. This study also aimed to develop natural absorbent pads using compostable spun, external layers, and biodegradable glue. A prototype sanitary napkin with biodegradable absorbent pads was developed and evaluated for absorption ability, absorption rate, pH, and biodegradability. The absorbent material absorbed up to 19 times its weight in 2 minutes and 33 times its weight in 2 hours, which is enough for an average of 80-150 mL of menstrual blood. The prototype napkin deteriorated within 99 days, based on naked eye observation. Some signs of degradation and microorganisms growing on the prototype were also observed from scanning electron microscopic images. According to the findings, natural absorbent pads made from malva nut have the potential to be converted into sanitary napkins. Furthermore, it is proposed that the components, which include superabsorbent renewable materials, spinning compostable layer, external compostable layer and biodegradable glue, may be used in a variety of goods, including adult diaper pants, incontinence pads, and laboratory bench mats.

Currently, no method can completely eliminate the human immunodeficiency virus (HIV) in an infected person. HIV employs an accessory protein called Nef that forms a complex with cellular AP-1, preventing detection of HIV-infected cells. Lovastatin has been recently identified to inhibit the formation of said Nef-AP-1 complex, but its effective concentration is remarked to be far higher than other Nef inhibitors. This study aims to develop a modified lovastatin molecule exhibiting higher binding affinity to the HIV-1 Nef protein than lovastatin in silico. Modified lovastatin molecules based on the interaction map of lovastatin with Nef were modeled, and flexible ligand-flexible receptor docking to the Nef binding site was performed using AutoDock Vina. Residues within the Nef binding site identified by Liu et al. (2019) to be crucial (Glu-63, Val-66, Phe-68, Asp-108, Leu-112, Tyr-115) were set as flexible. Fragment-based drug design was utilized to append molecular fragments to lovastatin in order to maximize its interactions with said crucial residues. From the fragment-based approach, molecule F4 ((1S,3S)‐8‐{2‐[(2R,4R)‐4‐chloro‐6‐oxooxan‐2‐yl]ethyl}‐3‐(hydroxymethyl)‐7‐methyl‐1,2,3,4‐tetrahydronaphthalen‐1‐yl 4‐aminobenzoate) exhibited a binding affinity of -9.0 kcal/mole, and its estimated IC50 ranges between 0.25-0.51 μM which is at least 7.5 times lower than the reported IC50 of lovastatin from literature. This study presents insights on the key modifications to improve lovastatin as an HIV-1 Nef inhibitor and pertinent information about the Nef binding site for future drug development studies.