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以隨手可得拍攝影像的工具(如智慧型手機、個人數位助理、網路攝影機等)及網際網路的便利性,讓使用者能隨時透過書籍條碼影像向遠端資料庫查詢書籍的相關訊息。本研究以「ISBN書籍條碼」為例,經過條碼影像的擷取、偵測並分割出影像中的條碼、歪斜校正以及辨識後,透過網際網路,從ISBN書籍資料庫中查詢出該書籍的相關資訊,讓我們體驗行動通訊科技所帶來的便利。在程式的實作上,除了使用現有影像處理技術中的霍夫轉換與邊緣偵測外,也搭配上自行設計的變化量分配圖,使得ISBN條碼的辨識能力大為提升。此外,為了將使用者查詢時等待回應的時間降至最低,採用了記憶體直接存取的方法來處理影像外,也針對程式執行時的瓶頸部分,以平行處理的機制來加速,經過在Intel i5 M560四核心處理器上的實際測試,一幅900×675像素的影像,平均只要花費1.08秒即可辨識出ISBN條碼,相當的迅速。
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線上教學資源
科學探究怎麼做?借鏡法國IBSE的經驗
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野外實測嗜酸性溫泉紅藻光合作用能力之特性
台灣溫泉資源豐富,不同的溫泉泉質適合不同的溫泉藻類生長。溫泉藻屬於極端生物,其應用資源極待研究開發。本研究根據細胞型態、藻膽蛋白種類分析以及rbcL 基因定序等結果推測北投溫泉藻屬於一種溫泉紅藻,其種類近似於Galdieria sp. (Rhodophyta)。此外,本研究利用葉綠素螢光分析儀於野外實測北投溫泉紅藻於不同光強度下,光合作用能力的差異,發現適應於不同光強度的溫泉紅藻,其電子傳遞速率並無顯著的差異。推測其原因可能與北投溫泉紅藻的phycocyanin 含量會隨著光量有所調整,藉此達到最佳的光合作用能力有關。另外,本研究發現隨著光強度的上升,溫泉藻的NPQ 值有上升的趨勢,然而低光區的溫泉藻有較高的NPQ 值,此與一般理論不符。利用HPLC 分析北投溫泉紅藻的類胡蘿蔔素種類組成,其種類分別為Lutein、α-carotein、β-carotein 與Zeaxanthin,未發現Violanxanthin 與Antheraxanthin,北投溫泉紅藻並不俱有葉黃素迴圈。因此根據研究結果,我們認為NPQ 值與色素的關係仍有討論的空間Taiwan is resourceful in hot springs. Various hot spring algae are adapted to different types of hot springs. Hot spring algae applications are still under developing. In this work, based upon the morphology, analysis of phycobiliproteins, and rbcL sequences, the hot spring algae of Peitou is found to be Galdieria maxima (Rhodophyta). In addition, the dependence of the photosynthesis of Galdieria maxima on the light intensity was measured by Diving-PAM. The results show that the light energy availability efficiency of Galdieria maxima adapting to different light intensity exhibited different, although the electron circulate rate differed insignificantly. This suggests that the concentration of phycocyanin in Galdieria maxima may vary to attain optimal photosynthesis. Furthermore, the NPQ of Galdieria maxima increase with the light intensity. However, contradict to the theory; even under the same light intensity, the NPQ of Galdieria maxima was higher at low light zone. The carotene composition of Galdieria maxima was analyzed using HPLC and found lutein, α-carotene, β-carotene, and zeaxanthin. Violaxanthin and antheraxanthin were not present. Therefore, Galdieria maxima do not exhibit xanthophyll. Based on the results of this study, the correlation between NPQ and pigment still needs to be investigated.
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Asymmetric Total Synthesis of GlaxoSmithKline’s Potent Phosphodiesterase PDE IVb Inhibitor
Phosphodiestarase of subtype PDE IVb inhibitors are considered as perspective drugs for the treatment of the central nervous system disorders (depression, Alzheimer’s disease, Parkinson’s disease). Pyrrolizidinone Glaxo-1, proposed by GlaxoSmithKline, is a highly potent PDE IVb inhibitor (IC50 = 63 nM), then conventional phosphodiesterase inhibitors Ro-20-1724, Rolipram and Cilomilast. However the activity of the Glaxo-1 was studied on a racemic sample, since the asymmetric approach to its synthesis has not been developed. Therefore the purpose of this research was the development of an efficient synthetic scheme enabling enantioselective excess to both (-)- and (+)-Glaxo-1, which can be than subjected to biological studies. \r The key stage in proposed asymmetric synthesis (-)- and (+)-Glaxo-1 is stereoselective [4+2]-cycloaddition of the nitroolefin to an optically activity vinyl ethers, derived from (-)- or (+)-trans-2-phenylcyclohexanols. The resulting chiral cyclic nitronates are transformed into a functionalized cyclic oxime ethers using tandem sylilation-nucleophilic substitution procedure. Reduction and decarboxylation of these products lead to optically pure Glaxo-1 and the regeneration of chiral 2-phenylcyclohexanols (91%). \r Thus both enantiomers (+) and (-)-Glaxo-1 were obtained selectively in average yield 12% from isovaniline and nitroethane. The study of biological profiles of each enantiomer of Glaxo-1 will be conducted in near future.
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飛「波」傳「電」~6V電池直流電源之無線電力傳輸與充電
本次研究中,我們使用了直流電源進行感應電流的測試,實驗中發現,直流電源因為電流穩定,所以並無法產生感應電流,只有在一開始打開電源或關閉電源時才會有。於是我們用打點計時器設計了自動開啟與斷電的裝置,使直流電不斷地開啟與斷電,造成源源不斷地感應電流,但此裝置的輸出功率太小,於是我們使用了簡易的振盪器形成了振盪電路,使直流輸出的電源也可以有交流電的效果,透過多種測試,最後利用細線編織而成的麻花辮來繞線圈,解決因集膚效應所造成的損耗,接著利用倍壓式整流電路,將交流電轉成直流電搭配同步共振的電路,使原本的傳輸效率提升了2~3倍之多,而在充電式電容實際充電後發現,充電5分鐘,就可以使3V的LED燈泡點亮25分鐘以上。
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Vitamin C in Cold and Flu Drinks
This chemistry project was designed to measure the vitamin C levels within liquid cold and flu remedies, and see if they had been accurately stated on the package. A range of Cold and flu drinks was selected, including one made with only cold water (Lemsip Original, Lemsip Max, Effer-C-Cold Water, Relief and Lemting) .The procedure used to carry out the experiment was a redox titration, each trial required two titrations, with the first being a blank titration to determine a sodium thiosulfate concentration in the absence of vitamin C. The following Drinks had more Vitamin C than stated on the packaging – Lemsip Original (19.4%), Lemsip Max (22.1%), Effer-C (17%) and Relief (8.8%). Lemting was the only drink made to directions that had less Vitamin C than stated by 31.8%. Two conclusions can be drawn from these results, the first being that Lemting has the most inaccurately recorded mass of vitamin C and is also the only drink with less vitamin C than stated. The other interesting result is that Effer-C (the only drink made with cold water) had 170mg of extra vitamin C. Of the other drinks that had more vitamin C, Lemsip Max was next with an extra 22.8mg. Early research had showed that Vitamin C was affected by high temperatures (above approximately 70oC) and, as cold and flu drinks are commonly made with hot water the Vitamin C levels might change when they were made up. This poses a further possible research question which is, in making cold and flu remedies with hot water is some of the available Vitamin C being destroyed?
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「老師!我們已經花了快兩個鐘頭的時間,而且標本片也換了三、四片了,就是看不到草履蟲的食泡由紅色變成藍色,怎麼辦?」當我們做「草履蟲的營養與調節」的實驗時,若依照實驗指導的方法,用剛果紅粉末加酵母菌懸浮液一起煮沸,經草履蟲攝食後,形成鮮紅色的食泡。我們觀察了數十分鐘,食泡依然呈現紅色,並沒有變成藍色或其他顏色,與課本的理論不相符合。所以同學們都抱怨實驗做不出來而白白浪費時間,難道這是理論有錯誤嗎?因此我們懷疑這個實驗的設計可能有不妥之處,需要加以改進。
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生物世界數學遊戲—以碎形理論解釋植物的生長形態
芒萁是中低海拔常見優勢種,以往文獻提出的解釋是「適應台灣酸性土壤」,但我們提出另一假說:芒萁的羽狀複葉具有特殊的樹狀碎形生長形態,二分岔疊代循環,使其生長效率提高,具有較佳的生長優勢因而成為地被層優勢種。我們從野外生長形態及模擬生長模式進行驗證。野外調查結果,複葉枝條長度與分岔角度有遞減的趨勢,以降低末端小葉重疊比例而提高光合作用葉面積。軟體模擬結果,最佳生長模式為二分岔3階層且分岔長度比為1.0,分岔角度為100。重複二分岔次數模擬中以3階層效率最好,最差為6階層,此結果與野外生長狀況相符。從野外及模擬資料互相比對後,發現樹狀碎形生長模式能讓能量收支達最佳化,有較佳的生長效率,有助成為優勢種。
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The Use of Simulated Annealing in Predicting Solar Flare Activity
A program based on the simulated annealing (SA) algorithm was developed to allow for a longer-term prediction of the occurrence of solar flares, thus reducing the risks they may pose to astronauts, satellites, and ultimately the planet Earth. Sunspot data such as the solar cycle, the appearance of sunspots, the sun's magnetic field, the occurrence of solar flares and other factors that concern the sun were considered in the development of the algorithm. The program, coded in C++, included providing for an initial random state that pertained to the sun's state at a specified time. A neighborhood function was designed based on how sunspots are formed and how they disappear, and the probability function was designed using previous solar cycles to show relationships between the number of sunspots and the time it takes for the sun to reach solar maxima. Finally, the cooling function was designed as a representation of the time. Recorded sunspot counts obtained from the US National Geophysical Data Center (NGDC) during the solar cycle 22 from 1986 to 1996 was used as test data. The output was compared to the actual recorded solar events or the period. The program was found to be 66.7% accurate in predicting solar flares when compared on a smoothed trendline, while it exhibited a 50.5% accuracy when comparing day-to-day data. Since solar flare acitivty is predicted in terms of the trend of activity and intensity, improving daily data accuracy is superfluous. Smoothed trendline prediction accuracy may however be improved by altering the importance of each factor in predicting solar flare activity and by devising a different sunspot classification scheme for intensity and activity.
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傑克船長和他的海盜們掠奪到許多箱珍寶,每箱含有數量不等的金幣及鑽石。船員們深怕傑克船長又出什麼陰謀,一致同意讓船長任選一半的箱子拿走。\r 當然,傑克不知道金幣和鑽石的價格比,為了保證可以得到一半的利益,傑克希望他拿到的金幣和鑽石都各占一半。傑克的願望會實現嗎?\r 這個問題已用高等數學證明其解,而本研究利用初等數學的方法,除證明傑克需取的最少箱子數外,同時也能更快速的算出取法。\r 類似的結果可應用至分配災區物資等情形,或任何無法轉移、獨立的資源,如各式專長的人才、多功能的機械等,期望可對更有效的分配做出貢獻。
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The Flying Chloroplasts Drug Test
Previously, I studied the acute effects of a common broadleaf herbicide, Killex (by Montsano) and a pesticide, Spidercide (by Wilson), on cytoplasmic streaming in detached leaves from the pond weed, Elodea canadensis. I found that Killex, active ingredient 2-4D, an auxin analog, applied at the recommended dose decreased the rate of cytoplasmic streaming by 64% over a 20 minute observational period. The Spidercide, active ingredient d-trans allethrin, a Na+ channel activator, stopped cytoplasmic streaming after a 5 minute exposure and no recovery was observed during the 20 minute observational period.
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