The pharmaceutical industry is constantly searching for methods that allow drugs to be delivered as a direct response to a specific stimulus, in which the locus of delivery is in the vicinity of required region. A unique thermo?reversible hydrogel,F127 modified with dimethacrylate (DMA), that can deliver drugs at physiological temperatures was synthesized. Nanoparticles which are specific for targeting human body cancer cell were absorbed by this hydrogel. The toxicity of nanoparticles with different diameters and coating was measured using the MTT assay. It was found that nanoparticles with smaller diameters and folate coating were most toxic to the cancer cells. The release rate of the nanoparticles from the hydrogel was measured as a function of temperature with the hydrogel releasing approximately 3 L nanoparticles per hour. Exposing this drug delivery system to cancer cells would effectively inhibit MCF7 cell proliferation. By grafting this nanoparticle?loaded hydrogel onto a thermoelectric module, the release of the drug would be controlled. Thus, a successful temperature sensitive hydrogel was synthesized that releases cancer?targeting nanoparticles which inhibit cancer cell proliferation, thereby engineering a controlled drug delivery system.

寒假中，我有幸代表學校參加高雄市救國團所舉辦的冬令自強活動一一參觀認識十大建設工程。造船廠、煉鋼廠、高速公路……等偉大的工程建設，都令我產生身為現代中國人的榮耀。參觀過程中，給我印象最深刻的是任何工地上都有的一種類似怪手的機器一一挖土機。它操作迅速、便捷，一個大土丘不多久的時間便剷為平地，真是節省不少人力及時間。回到家裏，我久久不能忘懷，便急於著手研究其構造原理，得知「怪手」是以油壓原理來產生動力的。原理並不難，只是其動力來源一一油，比較昂貴，尤其在能源危機的今天，油的耗費便是成本的增加。是不是有比較廉價的動力來源可以取代石油呢？開學後，老師講解帕司卡原理，謂密閉容器內，液體某一點受壓力時，此壓力傳到容器內各處，其壓力大小不變。對！它只提到液體，為什麼不能用水這種液體呢？藉水壓代替油壓，不但節省能源，而且它取之不盡、用之不竭！

學習了力學之後加速度及能量的問題不停的圍繞著我們，但課本中所有的力學實驗大都由於計時裝置的不夠精確，而無法很完整的來滿足定理的要求，因此在寒假期問我們幾個同學換在一起，企圖自己設計出－套準確的計時工具和力學實驗裝置，來驗證課本中所告訴我們的力學性質。在計時工具方面，水鐘車以及微量天平的裝置，給了我們不少的啟示。加上電磁鐵的瞬間開關，我們終於設計出一套可以計時到千分之一秒以內的計時工具了，在力學裝置的儀器部分，我們想藉由二粒鋼珠在空問碰撞的相對位置關係上，找出運動學中所必須遵守的法則，進而探討位能與動能的轉換以及摩擦力所發生的效應：這樣我們不但能更充分的瞭解了課本中所斂述的力學原理，進而在自己動手的原則下，達成了學以致用的目標，並且在做過實驗後所得到的完整數據及資料中，我們又得到了豐碩的討論題材，從這些題材中，所獲得的寶貴知識，不但在開始時出乎我們的意料之外，其結果也確實讓我們興奮。

Sicherman 已經找出與兩顆六面的正常骰子有相同機率分布的Sicherman 骰子，並進一步獲得與三顆六面的正常骰子有相同機率分布的骰子必為一對Sicherman 骰子與一顆六面的正常骰子之結果，我們試圖由已知的Sicherman 六面骰子的處理方法出發，透過對割圓多項式的分析來累積足夠的相關資料，以處理由兩顆四面骰子至兩顆三十面骰子，處理由三顆四面骰子至三顆三十面骰子的各種Sicherman 骰子的答案，來探索兩顆與三顆的n 面Sicherman骰子存在的充要條件與求法，並進一步將所得之結果分類，得到 ”有相同標準分解式的類型的數n，會具有相同組數的Sicherman 骰子”之猜測結果與特殊情形下的證明。 Sicherman has found out the Sicherman dice which have the same probability distribution as the normal two six-sides dice. Furthermore , he also found out a pair of Sicherman dice and a normal six-sides dice has the same result as 3 normal six-sides dice . We try to begin with the given algorithm of six-sides Sicherman dice , through the analysis of Cyclotomic Polynomials to accumulate sufficient related information then to come up with the solution from discussion of 2 four-sides dice to 2 thirty-sides dice , from 3 four-sides dice to 3 thirty-sides dice to explore the existence of necessary and sufficient condition and solution of 2 n-sides Sicherman dice and 3- sides Sicherman dice , and even to classify the results to come to a conclusion of the guessing results and proofs under special cases about “the numbers n which have the same Canonical Prime Factorization will have the same numbers of n-sides Sicherman dice.”

This experiment mainly aims at three kinds of solution - Dextrose, Saccharose, and Fructose. By changing its temperature, density, length of tube, as well as different wave length factor of polarized light, we observe the influence of the direction of polarization by those factors. The experimental result showed as follow. The Dextrose and the Saccharose can cause the polarized light with the rotary direction of clockwise, so both are ‘dextrorotatory’. The Fructose can cause the polarized light with the direction of counterclockwise, so it is the ‘laevorotatory’. For the Dextrose, when the\r temperature is lower than 20℃, the direction of polarization has changed observably, but doesn’t have any rule. When the temperature is higher than 20℃, the direction of polarization increase slowly. For those three kinds of solution, when\r density increased, the polarization increased observably. When the polarized light passed through the solution with longer path, the direction of polarization has more change. When the wave length of the polarized light changed, the direction of polarization has been changed observably. When the wave length of the polarized light is shorter, the direction of polarization change increased.本實驗主要針對葡萄糖、蔗糖、及果糖等三種旋光性溶液，改變其溫度、濃度、容器管長、以及不同波長的偏振光等因子，觀察這些因素對偏振方向所造成的影響。實驗結果顯示：葡萄糖與蔗糖會使得偏振光的偏振方向以順時針旋轉，屬右旋性之光學異構物；果糖會使得偏振光的偏振方向以逆時針旋轉，屬左旋性之光學異構物。若溶液為葡萄糖，當溫度低於20℃時，偏振光的偏振方向會有明顯的改變，但無規則可尋；當溫度大於20℃時，偏振方向旋轉角位移則以非常緩慢的方式增加。當此三種溶液之濃度增加時，偏振光的偏振方向有明顯遞增的現象。此外，當容器長度越長（即偏振光在介質中的行程越長）時，偏振方向的改變亦越明顯。當偏振光的波長改變時，偏振光的偏振方向有明顯的變化，且當偏振光的波長越短，偏振方向的改變越大，似乎與波長呈反比，但此結果與理論值（即旋光度與波長平方成反比）仍有一些差距。

Purpose Although Body Mass Index (BMI) is accepted by the World Health Organisation (WHO) as the standard method of measuring a person’s obesity or lack thereof, it is restriction to the two measurements of height and weight. This makes its accuracy questionable. By using other easily obtainable body measurements, a better way of evaluating Body Mass Index is possible. The purpose of this project was to show that the BMI formula is only accurate to a certain degree and that its validity varies depending on certain factors used in my project. Procedure 50 Adolescent female aged 16-20 and 50 women aged 40-56 none of whom were noticeably obese or underweight volunteered. Using a simple questionnaire, several measurements were taken – age in months, caliper measurement of tricep and hip bone, shoe size, height in metres, hip waist and wrist measurements (cm), exercise per week, heart rate and body type. Results were tabulated and graphs drawn using EXCEL. BAI (Body Adiposity Index) measurements were calculated for all volunteers. Results The girls and women with pear and hourglass figures were classified by BMI as overweight or obese. The girls and women who exercised a lot were also unfairly classified by their BMI readings. Many of the graphs show that BMI is not accurate, however, others show that there is merit to the formula. Conclusions The results while interesting require a larger sample group to be conclusive. It would appear that the BMI formula needs to be extended in order to improve its accuracy. Further research includes: 1. Larger sample group, 2. Representative age groups, 3. Investigate males, 4. Look at data for different ethnic groups, 5. Research into BAI formula as a possible substitute, 6. Develop an improvement on BMI. Although, there is some merit to BMI formula, it could be greatly improved with the use of other measurements including those used in this project.

我們透過1970~2010年西北太平洋颱風的資料分析，探討聖嬰現象與颱風生成、路徑、強度和消亡的關係。我們發現，聖嬰現象發生時颱風較晚生成，颱風季較短，且生成後路徑偏北，東北亞國家受到颱風侵襲機率增加，反聖嬰時期颱風則較易侵襲東南亞。在夏季，臺灣於正常期比較容易受到颱風的侵襲，而反聖嬰現象發生時，秋颱侵台的機率增加，臺灣須嚴防秋颱的威脅。雖然聖嬰期颱風生成月份較晚，但生成位置遠離陸地，使平均壽命較長，颱風強度也易增強。統計結果也顯示，颱風的消亡與聖嬰現象無明顯關聯性。

我們想在畢業典禮時空拍同學們的影象，並即時投影在大布幕上，因此自行研發出了一個安全的飛行空拍機。我們選擇裝氦氣的中型氣球作為浮力來源；並探究各種市售遙控即時攝影裝置；同時嘗試改裝飛天小鯊魚、直升機、四軸飛行器，遙控小汽車及樂高機器人作為飛行動力。我們的飛行裝置必須同時讓浮力裝置、動力裝置、攝影裝置完美結合，我們在一連串的失敗中發現問題。終於成功研發出二種能在室內安全又穩定飛行的遙控飛行空拍裝置，飛天一號是以遙控小汽車改裝的輕巧型機種；飛天二號則是用樂高機器人，設計出能朝不同角度靈活移動的專業型機種。最後我們探討螺旋槳的大小和馬達的闗係，並改變氣球的排列方式，讓我們的裝置發揮最大的飛行空拍效能。

我們自然課上種子的構造和發芽的時候，老師要我們把綠豆浸一個晚上。在培養皿裡鋪棉花，把十粒浸過的綠豆，讓它發芽。我們從它們冒出胚根，長出莖葉……，一直觀察記錄到倒覆、枯萎。由這一試驗的結果，引起我們這一群研究不同植物發芽過程的興趣，並且嘗試作各種芽菜的培育。

金屬是屬於帶有自由電子的物體，因此有著金屬光澤、高延展性、易導電導熱等特徵。\r 汞即為水銀，是常溫常壓下唯一的液態金屬。不銹鋼的基本元素是鐵，還有其他金屬例如：鉻、鎳、鈦、鈷等，所以不銹鋼仍然屬於金屬原料。\r 水刀不是刀，它是將水加壓至很大的壓力然後從特製的噴嘴（噴嘴直徑非常小，大約是0.1mm到0.5mm）。水通過噴嘴時便會產生一道每秒將近1000公尺的水箭，此種高速水箭可以用來切割各種非金屬物質。如在水箭中加入高硬度細沙，則可增強其切割能力，可用來切割金屬等硬度較高的物質。

我們在化學課學到滲透壓的原理，且對於廣告商所推銷的磁石感到好奇，於是決定討論磁場對於滲透壓的影響。由無殼蛋的實驗發現磁場的存在會使蛋的滲透壓增加約45%，確實會影響滲透壓，但由不同的酸溶解蛋殼後，對於蛋膜的性質有不同影響，因此設計了一個實驗裝置，並以生蛋膜及玻璃紙為半透膜，選擇同濃度的蔗糖、氯化鈉等水溶液，在不同磁場強度下觀測溶液的滲透壓變化。從強度0、100、172、196、250、600、2250 高斯的磁場中，實驗得知磁場可影響滲透壓的臨界值約200 高斯，且得到不同磁場強度的滲透壓值，之後比較蛋膜與玻璃紙在有無磁場影響下的上升高度差值，得知磁場對蛋膜的影響遠大於對玻璃紙，固推測磁場對溶液滲透壓的影響主因是磁場具有改變生物半透膜的特性，所以許多人標榜磁場對人體的影響宣傳，再某些條件下是合理存在的。在不同溶質溶液的滲透壓實驗觀察發現；高中課程中的溶液介紹是以「理想溶液」為前提，故真正從實驗操作中才體會出真實溶液與理想溶液間的差異是有很大的距離，所以我們嘗試以真實溶液探討不同溶質與滲透壓的關係。