石英音叉是一種高精密的壓電震盪器，本研究欲利用其高靈敏度(高品質係數)，探討其作為表面感測器之可行性。將音叉調整在最佳的驅動震盪狀態，並將待測物固定在三維旋轉台上，藉由調節輪控制待測物的移動方向，使其緩慢移動並與探針接觸。當音叉受到表面凸起之微擾時，其靈敏的性質將使其失去共振，可藉此得知待測物表面之起伏。在本研究中，我們得到的結論是以石英音叉作為表面感測器是可行的，此外，石英音叉探針黏著點、使用的黏著劑、探針的材質以及探測方法會對感測器靈敏度產生影響。

Inhibitory effects of the secondary metabolite of actinomycete were examined on cell cycle of the yeasts of S. pombe and S. cerevisiae. The secondary metabolite was obtained from cultivation of the actinomycete isolated from the soil of Owakudani in Hakone, Japan. The fifth fraction of the secondary metabolite by ODS column separation (HK-T5), which was soluble to pure methanol, was used in the present experiments. The HK-T5 brought about the delay of forming colonies of S. pombe for about 11 days compared to that cultivated without the HK-T5. The delay of the colony formation was longer for the S. pombe cultivated with more amount of the HK-T5. The cultivation with HK-T5 also brought about the extension of the lifespan of the S. pombe for more than 10 weeks in a liquidus medium. The cell life recovered the ordinary manner by removal of the HK-T5, meaning that the activities of the HK-T5 is reversible. These facts confirm the suppression of cell cycle, and the delay of cell growth by the HK-T5. These phenomena were similarly observed for S. cerevisiae. Comparison of the action of HK-T5 with hydroxyurea, which is an anticancer drug inhibiting the cell cycle at S phase, clarified that the inhibitory action of HK-T5 worked at the phase earlier than S phase. The combined effects of HK-T5 on the cell cycle were evaluated with triamcinolone acetonide (TA), or aspirin, the former of which is a drug synchronizing cancer cells in S phase, and the latter keeping human cells in G1/G0 phases. The combined use of HK-T5 with TA synchronized the cells at the phase slightly proceeding from G1 to S phase without toxicity. On the other hand, the combined use with aspirin made the inhibitory effect of HK-T5 inactive. Hence, the HK-T5 is attractive as a drug for the extension of cell lifespan, and anticancer therapy.

本研究主要探討人類使用防曬乳進入水體後，對水生生物的影響。我們將防曬乳分為物理性和化學性防曬乳，依據不同濃度加入水體之中，觀察黑殼蝦成長和存活率變化，同時也觀察魚缸水體的改變，藉此初估探討不同種類防曬乳對環境和水生生物的影響。實驗進行一共七週，我們發現化學性防曬乳成分可以誘發綠藻大量生長，而物理性防曬乳可以促使矽藻生長。黑殼蝦在1ppm化學性防曬乳存在的環境中，生長和存活率不受影響，但濃度太高仍然會抑制其生存。物理性防曬乳則不論濃度多少，對黑殼蝦的影響相較於化學性防曬乳都較大。所以我們建議如果要進行水上活動，最好可以是用化學性防曬乳產品，減低對水域生態的危害和影響。

在生活當中我們時常會發現，飛機因為場地跑道不足而無法順利起降，或是航行時有許多不確定因素而不敢搭乘。本研究主要探討為:旋轉翼飛機是否能成為短距離起降之創新飛行器。在這研究過程中，主要是採用旋轉翼產生向上升力(向下推力)，並同時探討導風板數量多寡對於飛行穩定性的影響。最後，我們從實驗數據中找出黃金比例來設計飛機模型，再安裝電子加速度計陀螺儀及其他飛行安全裝置，使旋轉翼無人機在天空中能以平穩的姿態飛行，有效縮短了起降跑道距離，打破一般人對於現有飛機所既有的認知。

目前網路上流傳許多使用人工智慧修復照片的網站或應用軟體。然而，由於這些訓練資料多數來自國外，導致修復台灣「本地」照片的效果欠佳。此外，許多老舊照片因氧化、潮濕而泛黃，使得修復程序比起修復純黑白相片更加困難。因此，本研究旨在建立一個專門修復本地照片的機器學習模型，主要分為以下三個部分：首先，使用機器學習模型對老舊照片進行修復，包括著色、去模糊化和降噪；其次，分析使用不同比例之有色調照片(模擬泛黃照片)訓練模型的效果；最後，研究不同的修復順序(著色、去模糊化、降噪)和模型執行次數對照片修復效果的影響，發現「著色、去噪、去模糊化」的順序修復效果最佳。

在這個資訊發達的時代，網路充滿著五花八門的資訊，導致我們在查詢資料時會因為這些雜亂且未經過濾的資料浪費許多時間，其中最為氾濫的便是點擊誘餌（clickbait），此種新聞常常有著吸引人的標題，而內容卻不會與主題相符，人們也常常在讀完整篇文章後才意識到自己浪費了許多時間在無意義的資訊上面。解決此問題很常用的方法之一便是運用摘要演算法來讓讀者先對新聞有一個大概的理解，不過，雖然摘要演算法越來越普及，但產生出來的摘要仍會和人為判斷的結果有所差距，進而造成閱讀理解上的錯誤以及偏差，所以我們想要藉由這次研究，從一個嶄新的角度切入，探討摘要演算法和句型分析之間的關係，融合原本向量建構的方式以及語句結構的分析來測試摘要的準確度，並且由結果研發出一個可以產生出更為精確的主旨之摘要演算法，除此之外，我們也會融合實地調查以及搜集意見的方式來更進一步探討人們思模式與產生出的摘要之關聯性。

隨科技演進，大多數天然災害我們已有能力做到預報的工作，而少數尚未有準確預報系統的自然災害，地震－－即名列其中。故對於震災，熟稔預防工作、設計抗震、耐 震建築顯為首要之務。本研究透過水平搖晃槽及垂直震動器模擬地震發生時之S、P波 並以造型棒、頂點珠模擬鋼骨結構受震。觀測各異樓層、底面、抗震裝置下其搖晃程 度及破壞位置等，並探討：(一)建築物破壞點和抗震力關係、(二)建築和地震來向關 係、(三)梁柱、結構對稱性對耐震程度關係、(四)制震裝置等之功效。

Money drives the world and in times of crisis, money is more important than ever. Most political, economic and, as we have seen recently, health crises are accompanied by pressure on the economy. With such pressure, ordinary citizens are worried about their money, which is at risk either from inflation or from an uncertain economic outlook. In such times, some people resort to appreciating their money by investing. It is wise investments that can protect savings from inflation, or at least mitigate the effects of inflation. Investing in the stock market is among the most popular ways of investing. During the global coronavirus crisis, the number of small investors more than doubled (Galik and Brody [2022]), and in 2021, Covid (new) investors accounted for 15 % of investors in the U.S. market (Schwab [2021]). It is this phenomenon that inspired the author to write this paper. Investing in the stock market is one of the riskiest forms of investment, which means that there is a high probability of losing the originally invested capital. Some companies that allow retail investors to invest state that more than 90 % of their users lose their capital when investing in the stock market. On the other hand, investing in the stock market has one of the greatest potentials for profit. In the case of a long-term investment in index funds, for example, an average annual appreciation of between 8 % and 12 % can be expected (the average appreciation of the S&P 500, the most famous US index). However, it is necessary to wait several years for stable results. To see appreciation in a long-term portfolio, it is recommended to wait at least 12 years. This is because if a recession or a simple market correction comes, said portfolio can lose up to 50 % of its value in a year. But as history shows, markets do rise over the long term, and that is what long-term investors bet on, waiting for their capital to appreciate over time. But the market does not grow all the time. The market often changes price trends, and in some rare cases a long-term trend can reverse for up to several tens of months. This phenomenon, volatility, is attempted to be exploited by so-called speculators. A speculator is an investor who sells and buys in short periods of time and thus speculates on price movements. The speculator therefore needs a way to determine the likely behaviour of the price in the foreseeable future in order to make their trades profitable. The two main ways of analysing price behaviour are fundamental and technical analysis. And since fundamental analysis incorporates a large amount of diverse information into its predictions, this paper concentrates on working with technical analysis.

本研究期望能藉由探討聲波的相關物理特性，研發出具備環保且使用安全的滅火器。研究過程中，運用程式設計與藍芽無線傳輸的方式，傳輸並測試許多低頻的頻率，並深入探討其聲壓頻譜、聲壓、聲強、聲功率分布等物理特性。經由聲壓頻譜分布可找出最佳（穩定較高）的頻率，藉由聲波物理特性的探討，可瞭解為何聲波處於低頻時具有滅火的特性，再由3D PRINT技術設計出周邊輔助的裝置，並完成研究作品。

水中塑膠微粒嚴重危害生物的生存，本研究擬探討清除水中塑膠微粒的方法與原理，以制定清除的參考流程。先用油料吸附水中塑膠微粒，再利用鐵磁性吸油劑吸附含塑油料，最後用磁鐵吸起清除。研究分為兩部分探討，一、油料與塑膠吸附的情形與影響因素；二、吸油劑與油料的吸附效果。為了放大觀察塑膠微粒與油吸附的情形，用塑膠小圓片模擬塑膠微粒，並作為吸附效果的量化數據；用油層高度比例法來量化吸油劑的吸油效果；以燃燒法和促鏽法自製鐵磁性吸油劑，與市售鐵氧化物比較。結果發現，塑膠種類、油酸價、水溶液種類會影響塑膠與油料的吸附。以燃燒的鋼棉、鐵粉、四氧化三鐵作為吸油劑，進行三階段多層次處理可以節省成本，也減低水汙染。

缺氧（Hypoxia）在癌症中，影響腫瘤微環境（Tumor microenvironment，TME）的重塑扮演重要的角色。原位癌細胞與欲轉移之遠端器官的微環境間，會透過細胞外囊泡（extracellular vesicles，EVs）進行細胞間相互作用，對於轉移前腫瘤微環境（Pre-metastatic niche，PMN）的形成和轉移過程至關重要。 本研究目的在闡明缺氧條件下，肺腺癌如何透過產生的外囊泡重塑肝臟轉移前微環境。結果顯示缺氧刺激肺癌產生的細胞外泌體（Exosome）增加了肝臟星狀細胞（hepatic stellate cell，HSC）活化和血管生成。由於缺氧肺癌所分泌的EVs含有CD151蛋白，促進HSC的活化和血管新生。缺氧肺癌所產生的Exosome增 加了HSC和內皮細胞中FAK（focal adhesion kinase）、Src（SRC proto-oncogene, non-receptor tyrosine kinase）和AKT（AKT serine/threonine kinase）通路的激活。 總結此實驗證實了缺氧腫瘤衍生的Exosomes，探討其中富含的CD151機制，活化了HSC與特別的訊息傳遞於細胞中，調節肝臟PMN的形成。因此CD151可作為肺腺癌轉移至肝臟的新治療靶點。