When doing an experiment to produce colloidal ferric hydroxide, the bottom of the beaker used was colored in yellow-brown with thin film interference. This phenomenon is well-known, but the cause has not been clearly studied. As a result of the research, the coloration on the bottom of the beaker is caused by β-FeOOH forming a thin film which is chemically bonded with Si-OH on the glass surface. Also, the amount of β-FeOOH depends on the number of experiments, the area of the bottom of the beaker, and the concentration of FeCl3 aq. We found that it can be possible to determine the amount of β-FeOOH from the formula m=knsc and the adhesion constant was found to be 6.8✕10-3 (L/m2). In addition, from machine learning we predicted that the thin film thickness becomes thicker as it moves away from the center.

Infections by the Dengue virus (DENV) cause a disease amonghumansreferred to as Dengue fever, which causes thousands of fatalities globally. There is no existing treatment as of yet that successfully targets DENV. Among the factors thatdeterminetheentry of the virus and severity of the disease is the envelope(E) protein of DENV. This study aimed to examine forty antiviral phytochemicals enumeratedinpaststudiesaspossibleinhibitorstotheEprotein of DENV to provide candidates to aid in drug discovery against DENV. The phytochemicals were screened for their likelihood of inhibition of the E protein using AutoDock Suite and LigPlot+. Seven phytochemicals produced favorable binding affinities to the E protein, which are based on the interactions between the phytochemicals and amino acidsintheactivesiteoftheEprotein.Lipinski’s rule of 5 was then used to screen the seven phytochemicals for oral bioavailability. Glabridin has a binding affinity of -7.6 kcal/mol and was predicted to be orally bioavailable. This phytochemical interacts with amino acids in the E protein active site through hydrogen bonds to Asn355, andPhe337, as well as ten hydrophobic interactions. These interactions ensure that glabridin is able to specifically target and fit intotheactivesiteoftheEprotein, preventing its binding to the host cell and activating its viral proliferation. Glabridin is known to be found in the roots of licorice plants, providing anatural source for a possible cure for Dengue fever.

Certain specially structured ceramics, which can be used as biomaterials to replace bone, have recently started being utilized in the medical field. The aim of this study is to produce high-bioactivity silica from corn cob waste, a widely available organic material in nature, and combine it with calcium oxide (CaO) obtained by grinding organic mussel shell waste with high bioactivity. This combination is intended to synthesize dicalcium silicate (2CaO.SiO₂) to develop an alternative tissue scaffold with high bioactivity, capable of replacing bone, for existing titanium alloys. The goal is to incorporate this scaffold into PEEK (polyether ether ketone), a novel tissue scaffold material, at varying percentages to create a next-generation innovative bone substitute material. An additional objective is to demonstrate through biocompatibility tests that the produced ceramic-polymer biocomposite exhibits antibacterial activity against Staphylococcus aureus.

Semisynthetic penicillin, Amoxicillin, is a broad-spectrum antibiotic that is widely used to treat bacterial infections in children suffering ear, nose, and throat infections, genitourinary tract infections, skin infections, and lower respiratory tract infections1. This antibiotic works against both gram-positive and gram-negative bacteria, such as Listeria monocytogenes, Haemophilus influenza, Streptococcus pneumonia , Streptococcus pyogene and Escherichia coli1,2. It shows antibacterial activity by inhibiting dd-transpeptidase, which maintains the integrity of the bacterial cell wall which results in bacterial cell death due to a fragile cell wall3. Nonadherence to medication was associated with 50% of drug-related hospitalizations in children4. In order to improve adherence and influence clinical outcome, it is important to acknowledge the importance of drug palatability to children4–6. The currently available liquid suspension form of this antibiotic is administered to patients through oral/GI routes. It is also available in capsules or tablets for adults7–9. In the gastrointestinal tract, the drug has to withstand variable pH conditions and enzymatic degradation , mucus and mucosal barriers to survive resulting in limiting drug bioavailability10,11. In addition to conventional drug delivery formulations, nanofibers can be used to deliver drugs orally, topically, and through buccal or transdermal routes12. Drug-loaded nanofibers offer many advantages as a delivery system, including their porous structure and their efficient delivery of various drugs and bioactive molecules including hydrophobic and hydrophilic drugs12–14. Considering that amoxicillin palatability can affect children patients’ compliance and due to the advantages of both nanofiber drug delivery system and drug delivery through buccal routes, hence, this project aims to prepare flavored electrospun nanofibers loaded with amoxicillin to mask the unpleasant taste of the drug for treating children with bacterial infection. Nanofibers loaded with amoxicillin can be applied between the child's gum and cheek, allowing the fibers to dissolve in mucus and penetrate directly into the bloodstream.

連結記憶(Associative Memory)為記憶兩物體之間關係的能力，會隨著年齡增加而衰退。先前研究顯示不同性別在記憶的老化程度存在差異，然而針對連結記憶在不同性別的老化未被討論。過去研究發現自我參照效應以及改變刺激材料的社會訊息程度可提升連結記憶的表現。然而缺乏同時使用兩種方法研究，兩者之間的交互作用尚不清楚。本實驗分別針對不同年齡與性別的群體進行連結記憶測驗。我們引導受試者使用自我參照記憶具有不同社會訊息程度的圖片，測量其連結記憶表現。結果顯示，女性有顯著的連結記憶衰退；而男性沒有顯著的連結記憶衰退，其記憶衰退可能與項目記憶有關。另外，我們也觀察到參照與社會訊息對連結記憶的影響具有交互作用，在未來實驗中有必要注意兩者之間的互相影響。

校園安全一直是各界關注焦點，然而，廣闊校園仍有許多潛在危險，特別是被建築物、設施或樹木遮蔽視線區域，是否因此增加安全疑慮？本研究透過1.問卷調查2.軟體分析3.實地觀察數據相互比對，發現以下幾點： 1.師生對校園內常用及不安全空間的認知具高度一致。 2.師生感到不安全的空間與軟體分析視線遮蔽區域吻合。 3.辦公室地理位置，對於人員動線的掌握具顯著效果。 4.實地觀察之記錄與問卷、軟體分析結果相似。 結果顯示空間規劃與校園安全之間的重要關聯，為提升校園安全提供參考依據，本研究藉此檢視校園內之警監系統及自動照明，發現設置尚為完備，但為更進一步達到告警效果，我們加裝告警設備，提醒小朋友不要進入學校危險區域。

本研究主要是以晶片和織布進行結合，以電極收集訊號分析受測者的鈉濃度和汗液流量，研發長期保持潤濕和擁有穩定性的高親水性薄膜Polyacrylic acid / Cellulose nanocrystals（PAA / CNC）感測器。製備不同濃度比例的PAA / CNC光固化水凝膠，進行接觸角、FTIR圖譜、溶脹比 (Swelling Ratio)、SEM、EIS 潤濕面積分析並比較選擇出PAA /10 CNC的濃度比例作為最佳的汗液感測電極。利用CNC與PET片間貼合度強化結果，能有效提升薄膜親水性，降低電極與織布中的親疏水性差異，加強電極感測靈敏度，相較於對照組，電容值結果顯示約提升5~10倍的靈敏度。本研究開發一個靈敏且穩定即時監測汗液的薄膜，並結合藍芽應用於智慧裝置。

The economy around the world is changing rapidly, with new ways of industrial production being introduced all the time. This is due to the Fourth Industrial Revolution. The main objectives of Industry 4.0 [5] are digitalization and full automation of production processes, which increase productivity and worker safety.

Space Medicine and relevant sciences are still considered a new era; the first humankind steps toward the space took place since less than 60 years. It has been noticed the adverse effects of microgravity on the human body in different aspects, our concern here is the musculoskeletal aspect. On the ground we didn’t notice how we can stand up, or how our muscles and bones of the lower limbs can keep us standing up right. This is by a complicated process including the bones, the equilibrium, and the anti-gravitational muscles of the lower limbs which occurred without thinking about it. The force of Earth gravity against our bones of the lower limbs makes them harder and makes the muscles stronger, because they are interfacing the earth gravitational force every moment we are standing up, as per Newton’s third law (for every action in nature there is an equal and opposite reaction), such forces are unavailable in space and its effect being obvious on arrival to earth after long stay space flights, so being unable to keep standing upright easily on their arrival. On return to earth the routine medical examinations revealed loss of astronaut muscle mass and bone density particularly of their lower extremities because they did not use them in space for a long time. Currently, astronauts on board of ISS (International Space Station) they accomplish daily tasks including resistive exercises ARED “Advanced Resistive Exercise Device” in form of treadmill, ergometer, and weightlifting machine, to decrease the loss of bone density and muscle mass of their lower limbs. Despite their discipline to those exercises they still lose 1-2% of the muscle mass and bone density that give importance to add some protective measures to keep their muscles and bones healthy. Through this article, the idea is to make a device such AACT (Automated Alternative Compression/Traction) to be applied daily to the astronauts lower limbs as part of their daily exercise during space flight to give push/traction forces to astronauts lower limbs to prevent or at least decrease such loss, by AACT we are mimicking the gravitational force of earth on astounds lower limbs during long space flights to let them be healthy till they come back.

沃辛頓射流是指物體掉入液體中後，在液體下形成空腔，經由表面張力的作用，空腔收縮並向上噴射的水流。瞭解射流機制與抑制射流引發的噴濺，在機械潤滑與公衛領域是重要的課題。本研究透過空腔與容器的交互作用，影響射流的形成空腔形變會改變表面張力的合力方向，使得局部收縮速率不同，進而影響射流的高度與方向。透過改變空腔兩側形變的程度，我們可以有效控制射流偏移方向，本研究進一步透過自製頂針，讓空腔局部變形，藉此產生射流偏移，證實張力波並非射流偏移的主要因素。本研究的成果，為射流的 研究提供一個新的觀點：空腔弧度大小決定收縮速率與方向，未來可藉此影響空腔收縮，協助科學家降低空蝕現象對機械的破壞。

台灣發生「土石流」頻繁，所以興建防砂壩已經是常態，然而，大量的泥砂使得防砂壩儲砂空間飽和，降低攔阻效能。因此，本研究的目的，希望找出影響調整型鋼管壩儲砂空間的因素並提出調整模式，以因應 台灣多變的氣候環境。經研究結論如下：一、壩後淤滿時，透過反覆調整鋼管壩開口，可以增加儲砂空間率，壩體的再攔阻率也會提升14.2%；二、建議枯水期調整橫桿或縱材，利用豐水期增加壩後的儲砂空間；三、壩後巨礫+粗礫逐漸提高，不利於增加儲砂空間率；四、壩後淤滿有漂流木，會造成儲砂空間率大幅降低；五、我們提出調階段性調整鋼管壩，第(一)、拆除中央橫桿、第(二)、拆除縱材、第(三)、拆除加深模式，可以增加儲砂空間並減緩土石流的衝擊。 >

本研究先觀察著名的密克定理（Miquel theorem）與密克點（Miquel point），我們創新給出了新的研究項目，關注密克點𝑃與密克三角形的頂點所構成直線和原三角形𝐴𝐵𝐶三邊直線的其餘六個交點，這是前人沒有觸及的研究項目，從而定義旁接三角形與衍伸三角形。 我們先針對特殊型（直角）的構圖，發現滿足兩個衍伸三角形的有向面積 [𝐴1𝐵1𝐶1]=±[𝐴2𝐵2𝐶2] 時，𝑃 點形成的軌跡為原三角形的 Kiepert hyperbola 與外接圓，這個是有趣且重要發現，我們也進一步給出其幾何必然性。進一步考慮 [𝐴1𝐵1𝐶1]=𝑟[𝐴2𝐵2𝐶2] 時，則刻劃出 𝑃 點軌跡為圓錐曲線系。在前面的基礎下，再針對一般型（任意角）的構圖，若 𝑃 點位於原三角形外接圓及Kiepert hyperbola 與 Steiner circumellipse 的線性組合曲線上，此時兩個衍伸三角形 𝐴1𝐵1𝐶1 與 𝐴2𝐵2𝐶2 的有向面積比值為定值，且兩者恆為相反數。