全國中小學科展

A Novel Approach of Gene Knockdown in Zebrafish through Targeted mRNA Cleavage

科展類別

臺灣國際科展

屆次

2004年

科別

微生物學

得獎情形

第一名

學校名稱

Raffles Junior College

指導老師

Cheong-Gek Yin Hwee

作者

Ben Yee Ming Leslie

關鍵字

Targeted mRNA Cleavage

摘要或動機

The zebrafish (Danio rerio) is a popular model organism used for elucidating complex\r
developmental pathways and processes. Although the Zebrafish Genome Project is\r
nearing completion, the function of most genes remains to be discovered. In zebrafish,\r
where an efficient gene targeting method is still absent, costly Morpholinos (MOs) have\r
been widely used to ‘knockdown’ specific genes.

A Novel Approach of Gene Knockdown in Zebrafish through Targeted mRNA Cleavage

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