全國中小學科展

Stimuli-responsive Fullerene Grafted Polymers for Enhanced Drug Delivery Applications

科展類別

臺灣國際科展

屆次

2005年

科別

生物化學

得獎情形

第二名

學校名稱

Anglo-Chinese Junior College

作者

Chai Jishan

關鍵字

Stimuli-responsive Fullerene Grafted Polymers

摘要或動機

The physiochemical properties of fullerenes have aroused wide interest, such as its ability to accept and lose electrons and relatively high reactivity that permit various modes of structural modifications. However, obstacles to further research include its complete lack of solubility in water and low processability.\r
This project investigated the morphology and microstructure of a fullerene-grafted polymer as a potential candidate for better and novel systems for drug delivery. In this research, hydrophilic functionalities were introduced to the C60 fullerene by chemical modifications, through the attachment of poly(acrylic acid) (PAA) chain. The objective was to investigate the dynamics and the self-assembly properties of this polymer in aqueous solutions, and the knowledge gained would enhance the development of such system for potential applications in drug delivery and nanotechnology.

Stimuli-responsive Fullerene Grafted Polymers for Enhanced Drug Delivery Applications

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