臺灣國際科展

醫學與健康科學

Finding a Better Brain Booster

The purpose of my project was to determine which activity improved academic performance the most: 10...

綠茶多酚EGCG對小腦萎縮抗氧化保護之探究

小腦萎縮症第三型SCA3為體染色體顯性遺傳疾病。已知為CAG三核甘酸重複序列數目過多的動態突變,造成polyQ在腦部神經細胞核內形成包含體,這種蛋白在細胞內長期堆積會導致細胞退化並死亡。此外,在SCA...

Expression of TRPV5 in Astrocytes: Implications for Ischemic Stroke

Elevation of intracellular calcium secondary to increased calcium influx along with increased gliosi...

探討CID384634合併臨床賀爾蒙治療用藥tamoxifen對三陰性乳癌的作用機轉

乳癌是台灣女性死因第四名,其中的三陰性乳癌因具備高轉移力,又缺乏特定受體而不適用於標靶藥物治療或賀爾蒙治療法,所以其治療方法有其困難度。CID384634為2-phenynaphthyridone(2...

Chitosan Defies Death

Gangrene is the death of tissue of certain parts of the body. In Indonesia, people who suffer from D...

誘發肺癌細胞產生細胞凋亡之天然物篩選及其機轉探討

癌症多年來為台灣地區十大死亡原因之首,因此,開發治療癌症的藥物有迫切的需要。本實驗先以SRB assay篩選許多天然化合物,並找到天然物「禾本科竹節草(Chrysopogon aciculatus)成...

The Interplay of Iron and α-synuclein in mediating Neuroinflammation in Parkinson’s Disease

Neuroinflammation is implicated as a contributive factor to neurodegeneration in Parkinson’s d...

結合奈米金粒與DNA適體的金黃色葡萄球菌快速檢測系統

金黃色葡萄球菌是生活中常見的病原菌之一,因其抗藥性日益嚴重,是大家所熟知的超級細菌。 目前醫院對此菌的檢測方式,從培養到獲得結果大約需要兩天,對許多感染此菌的重症患者是無法接受的醫療時間延誤。 有鑑於...

YWHAZ(14-3-3ζ)蛋白在肺腺癌細胞中可能活化Wnt路徑之探討

YWHAZ(14-3-3δ)蛋白被證實在肺腺癌中會引發上皮-間葉的轉變作用(epithelial - mesenchymal transition ; EMT)導致癌轉移,然而其分子機制卻...

Association of a Novel Hsp70 Species with Brain Aging and Proteasome Dysfunction

Most neurological diseases are characterized by the presence of protein aggregates,\rsuggesting that...