臺灣國際科展

Stimuli-responsive Fullerene Grafted Polymers for Enhanced Drug Delivery Applications

科展類別
臺灣國際科展
屆次
2005年
科別
生物化學
得獎情形
第二名
學校名稱
Anglo-Chinese Junior College
作者
Chai Jishan
關鍵字
Stimuli-responsive Fullerene Grafted Polymers

摘要或動機

The physiochemical properties of fullerenes have aroused wide interest, such as its ability to accept and lose electrons and relatively high reactivity that permit various modes of structural modifications. However, obstacles to further research include its complete lack of solubility in water and low processability.\r
This project investigated the morphology and microstructure of a fullerene-grafted polymer as a potential candidate for better and novel systems for drug delivery. In this research, hydrophilic functionalities were introduced to the C60 fullerene by chemical modifications, through the attachment of poly(acrylic acid) (PAA) chain. The objective was to investigate the dynamics and the self-assembly properties of this polymer in aqueous solutions, and the knowledge gained would enhance the development of such system for potential applications in drug delivery and nanotechnology.


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Stimuli-responsive Fullerene Grafted Polymers for Enhanced Drug Delivery Applications 72 KB Adobe Reader(Pdf)檔案